Search Results
105 items found for "Jillian G Baker"
- Full Agenda for Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
AM Session II AGPCR signaling pathways and trafficking Yuling Feng · Monserrat Avila Zozaya · Erwin G. on GAIN Domain Autoproteolysis Andrew Dates Heterogeneity of Tethered Agonist Signaling in Adhesion G Not Autoproteolytically Processed By The GAIN Domain Rashed Rezwan Parag Novel isoforms of adhesion G of GPR56/ADGRG1 via the characterization of a non-cleavable point mutant knock-in mouse, H381S Erwin G. compact multidomain module of fourteen domains which regulates signaling Nicole Perry-Hauser Adhesion G
- Ep 82 with Dr. Lauren M. Slosky
Slosky’s research is focused on understanding how neuropeptide G protein-coupled receptors (GPCRs) regulate Marc G. Caron at Duke University. Dr. These ligands stimulate receptor β-arrestin recruitment without activating canonical G protein signaling Slosky’s work has been recognized through several travel and research awards, including the William James
- Olfactory Receptors and Tumorigenesis: Implications for Diagnosis and Targeted Therapy
Targeted Therapy Published date October 4, 2024 Abstract "Olfactory receptors (ORs) are a class of G Authors Yi Tang, Ye Tian, Chun-Xia Zhang, Guo-Tai Wang Tags G Protein-coupled receptors , Olfactory receptors
- Ep 79 with Dr. Graeme Milligan
Graeme Milligan About Dr. Graeme Milligan Professor Graeme Milligan is Gardiner Professor of Biochemistry, Dean of Research, and His main research group centers on the function, structure, and regulation of G protein-coupled receptors Milligan has published more than 550 peer-reviewed articles and his research has been cited more than Milligan is the co-founder of both Caldan Therapeutics (2015) which discovers novel therapeutics for
- GprC of the nematode-trapping fungus Arthrobotrys flagrans activates mitochondria and reprograms fungal cells for nematode hunting
the nematode-trapping fungus, Arthrobotrys flagrans, that both are achieved through a dual-function G-protein-coupled revealed that ascarosides activate the fungal GPCR, GprC, at the plasma membrane and together with the G-protein elegans SRBC64/66 and DAF38 share ascaroside-binding sites with the fungal GprC receptor, suggesting 400-million-year
- LPA1-mediated inhibition of CXCR4 attenuates CXCL12-induced signaling and cell migration
CXCL12-induced signaling and cell migration Published date September 25, 2023 Abstract "Background: G functional implications of the CXCR4-LPA1 heteromer, we performed various assays, including cAMP, BRET for G Lee , Dong-Seung Seen , Jae-Yeon Jeong , Won-Ki Huh Tags Cancer , Chemokine receptor 4 , Chemotaxis , G
- Orphan receptor GPR50 attenuates inflammation and insulin signaling in 3T3-L1 preadipocytes
G protein-coupled receptors (GPCRs) are involved in endocrine and metabolic processes as well as many GPR50 (G protein-coupled receptor 50) is an orphan GPCR that shares the highest sequence homology with
- Genetic Deletion of Atypical VGLUT3 Rescues Huntington’s Disease Phenotype and Neurodegeneration in zQ175 Mice
Friday, November 3rd / 2:10 PM About Karim Ibrahim "A postdoctoral researcher, interested in studying G-protein
- Leukotriene B4 receptor 2 governs macrophage migration during tissue inflammation
Authors Ebru Ermis , Titli Nargis , Kierstin Webster , Sarah A Tersey , Ryan M Anderson , Raghavendra G Mirmira Tags G-protein coupled receptor (GPCR) , Macrophage , inflammation , metabolism , mouse , zebrafish
- C5aR2 receptor: The genomic twin of the flamboyant C5aR1
The C5aR1 is a classical G-protein-coupled receptor (GPCR), whereas C5aR2 is a nonclassical GPCR that tailors immune cell activity potentially through β-arrestins rather than G-proteins.
- Ep 113 with Dr. Prasenjit Saha
Specifically, I am interested in understanding dysregulated G-protein coupled receptor (GPCR) signaling More recently, I have shifted my focus to identifying allosteric modulators of host G-protein-coupled
- Wnt pathway inhibition with the porcupine inhibitor LGK974 decreases trabecular bone but not fibrosis in a murine model with fibrotic bone
trabecular bone but not fibrosis in a murine model with fibrotic bone Published date May 1, 2024 Abstract "G pathway inhibition , fibrotic bone disease , fibrous dysplasia (FD) , osteoblasts , trabecular bone , G-protein
- Comparative Analysis of the GNAI Family Genes in Glioblastoma through Transcriptomics and Single-Cell Technologies
We investigated the prognostic values of the guanine nucleotide-binding protein G(i) alpha subunit (GNAI Ta , Do Thi Minh Xuan , Sanskriti Dey , Sachin Kumar , Adrian Wangsawijaya Santoso , Bianca Tobias William , Chih-Yang Wang Tags G-protein-coupled receptor (GPCR) , genome , glioblastoma , malignancy , molecular
- Dr. GPCR Community Presentation | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
research was focused on investigating the cellular effects of missense lung cancer-mutations in the G-protein-coupled
- Ep 77 with Martin Audet
the Institute of Pharmacology of Sherbrooke and is an emerging leader in the structural biology of G
- Session VI | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
degeneration Yimin Zou Antibody-drug conjugates targeting CD97 in glioblastoma Dimitris Placantonakis Adhesion G Several adhesion G protein-coupled receptors (aGPCRs) have recently been shown to play critical roles Dimitris Placantonakis on the web Placantonakis Lab Google Scholar LinkedIn Adhesion G protein-coupled research scientist endeavoring to build a productive, independent scientific research career in adhesion G
- Ep 156 with Dr. Justin English
developing and innovating technologies to solve broad questions in pharmacology, with a specific focus on G-protein
- Ep 86 with Nicole (Nicki) Perry-Hauser
research fellow endeavoring to build a productive, independent scientific research career in adhesion G
- Stimulation of ectopically expressed muscarinic receptors induces IFN-γ but suppresses IL-2 production by inhibiting activation of pAKT pathways in primary T cells
Previously, we reported that the G-protein-coupled human muscarinic receptor could bypass tyrosine kinases Here, we demonstrate that stimulating G-protein-coupled muscarinic receptors (M1 and synthetic hM3Dq)
- Ep 155 with Endocrine Metabolic GPCR Organizers
Francisco with Professor Mark von Zastrow where she identified novel core cellular machinery critical for G continued to undertake postdoctoral research in Oxford, investigating the signalling and trafficking of the G
- GPCR Retreat 2023 - Part II
William Cole at the University of Calgary in 2010 for his Ph.D. where he studied the molecular basis Molecular Medicine and Neuroscience at the University of Ottawa as a Postdoctoral Fellow to explore novel G Sakmar’s laboratory at The Rockefeller University, where she study’s the signaling and degradation of G
- Ep 99 with Yamina Berchihce
GPCR, an ecosystem designed to bring together stakeholders interested in using G-Protein Coupled Receptors
- Ep 49 with Dr. Sudha Shenoy
Shenoy’s postdoctoral research discovered that ubiquitination of mammalian G protein-coupled receptors
- Ep 120 with Brendan Wilkins
research assistant at the Victor Chang Cardiac Research Institute where he investigated the orphan G
- Ep 124 with Gáspár Pándy-Szekeres
multiple areas of GPCR research such as sequence alignments, generic numbering systems, structure data, G
- Ep 157 with Dr. Nagarajan Vaidehi
contributions in developing constrained molecular dynamics simulation methods with emphasis on application to G-protein
- Developing a PROTAC to Degrade the Constitutively Active Onco-GPCR in Uveal Melanoma
Thomas Sakmar’s laboratory at Rockefeller University, where she studies the signaling and degradation of G
- The power of many: Multilevel targeting of representative chemokine and metabolite GPCRs in personalized cancer therapy
chemokine and metabolite GPCRs in personalized cancer therapy Published date September 12, 2024 Abstract "G