Search Results
48 items found for "Leigh C Walker"
- Systems modeling of oncogenic G-protein and GPCR signaling reveals unexpected differences in downstream pathway activation
Nadia Arang, Kathryn Lande, Navneet Kaur, Melinda Tong, Mathieu Bakhoum, J Silvio Gutkind , Edward C
- Gi/o GPCRs drive the formation of actin-rich tunneling nanotubes in cancer cells via a Gβγ/PKCα/FARP1/Cdc42 axis
Subsequent signaling analysis reveals a strict requirement of phospholipase C β3 (PLCβ3) and its downstream
- NPFF stimulates human ovarian cancer cell invasion by upregulating MMP-9 via ERK1/2 signaling
Authors Ze Wu , Qiongqiong Jia , Boqun Liu , Lanlan Fang , Peter C K Leung , Jung-Chien Cheng Tags Invasion
- Neurotoxicity and accumulation of CPPD quinone at environmentally relevant concentrations in Caenorhabditis elegans
Authors Xin Wan, Geyu Liang, Dayong Wang Tags Accumulation , C. elegans , CPPDQ , Neurotoxicity Source
- C5aR2 receptor: The genomic twin of the flamboyant C5aR1
generating highly refined model structures of C5aR2, respectively in free (inactive), complexed to C-terminal
- Stretch regulates alveologenesis and homeostasis via mesenchymal Gαq/11-mediated TGFβ2 activation
Joseph , Anthony Habgood , Amanda L Tatler , Katalin Susztak , Matthew Palmer , Stefan Offermanns , Neil C
- Delivery of US28 by incoming HCMV particles rapidly attenuates Akt activity to suppress HCMV lytic replication in monocytes
Biswas, Michael J Miller, Julia E Myers, Stephen M Matthews, Amanda B Wass, Christine M O'Connor, Gary C
- TIPE proteins control directed migration of human T cells by directing GPCR and lipid second messenger signaling
deletion and site-directed mutagenesis, we established that Gαi interacted with TNFAIP8 through its C
- Deciphering a GPCR-lncRNA-miRNA Nexus: Identification of an Aberrant Therapeutic Target in Ovarian Cancer
effectively neutralizing their tumor-suppressive functions involving key oncogenes such as Ras and c-Myc
- Wnt pathway inhibition with the porcupine inhibitor LGK974 decreases trabecular bone but not fibrosis in a murine model with fibrotic bone
L Wentworth, Tania Moody, Ariane Zamarioli, Apsara Ram, Gauri Ganesh, Misun Kang, Sunita Ho, Edward C
- Session V | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
We assign the N-terminal CADH1-8 module as necessary for cell adhesion and we show the C-terminal CAHD9 Authors & Affiliations "Garbett, Krassimira, Kordon, Szymon P., Shearer, Tanner, Sando, Richard C.*,
- Ep 145 with Dr John Janetzko
Daniel Kahne and Suzanne Walker studying the structure and function of the essential human enzyme, O-GlcNAc Journey and Lab Collaboration John discussed his scientific journey, starting with a project in Suzanne Walker's
- GPR68-ATF4 signaling is a novel prosurvival pathway in glioblastoma activated by acidic extracellular microenvironment
Jovanni D Ahmad , Konstantin G Birukov , Anna Birukova , Henry Brem , Betty Tyler , Eli E Bar , Charles C
- Session I | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Affiliations "Rosell, Júlia (1) Holmkvist, Jesper L. (1) Arastoo, Mohammad Reza (1) Vejre, Phillip C. Burruss (Harvard Medical School); Andrew Kruse (Harvard Medical School); Stephen C.
- Chemokine N-terminal-derived peptides differentially regulate signaling by the receptors CCR1 and CCR5
Authors Olav Larsen , Sara Schuermans , Anna Walser , Stavroula Louka , Ida Aaberg Lillethorup , Jon
- Session III | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
autoproteolytic cleavage in the GAIN domain, creating a heterodimer of an N-terminal fragment (NTF) and a C-terminal
- Terms and Conditions | Dr. GPCR Ecosystem
that interferes with or disrupts the integrity or performance of the Services or its components, or (c) ; (b) changes to conform and adapt to technical requirements of connecting networks or devices and (c)
- Session II | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
GPCR-autoproteolysis site (GPS) enclosed within the larger GAIN domain to generate the N-terminal (NTF) and C-terminal
- Posters | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
hypothesis, we created WNT-like MB cell lines stably expressing tet-on wild-type BAI3 or a BAI3 lacking the C-terminal
- Student Flash Presentations | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
"Srivastava, Swati1; Singh, Abhishek Kumar1; Gunawan, Felix2; Gentile, Alessandra2; Petersen, Sarah C.3