Search Results
119 items found for "Lipid metabolism"
- đ° GPCR Weekly News
GPCRs in Cardiology, Endocrinology, and Taste Metabolic depletion of sphingolipids inhibits agonist-induced Lipid Modulation of a Class B GPCR: Elucidating the Modulatory Role of PI(4,5)P2 Lipids.
- CD28 and chemokine receptors: Signalling amplifiers at the immunological synapse
During years, several studies have depicted the pivotal role of the cytoskeleton and lipid microdomains
- Structures of oxysterol sensor EBI2/GPR183, a key regulator of the immune response
reveal an agonist binding site for the oxysterol and a potential ligand entrance site exposed to the lipid
- Targeting CXCR1 and CXCR2 receptors in cardiovascular diseases
These effects include reducing the atherosclerotic plaque area, improving the serum lipid profile, attenuation
- đ° GPCR Weekly News, May 6 to 12, 2024
Alejandra Tomas, et al. for their study on Lipid regulation of the glucagon receptor family Drs. response to exercise training are associated with tissue-specific transcriptomic and epigenomic signatures Lipid glucagon receptor family Technologies for the discovery of G protein-coupled receptor-targeting biologics Lipid
- Targeting CXCR1 and CXCR2 receptors in cardiovascular diseases
These effects include reducing the atherosclerotic plaque area, improving the serum lipid profile, attenuation
- đ° GPCR Weekly News, June 19 to 25, 2023
Specialized Pro-resolving Lipid Mediators and Resolution of Viral Diseases. Inversago Pharma Presents Data from Phase 1b Trial of INV-202, a Peripheral CB1r Blocker for Metabolic
- đ° GPCR Weekly News, January 23 to 29, 2023
Physics and Astronomy Postdoctoral Research Associate (Fixed Term) PhD Project - Investigating the lipid regulation of GPCR signalling Postdoctoral Fellow - Molecular Dynamics Postdoc in lipid regulation of
- Pepducin-mediated G Protein-Coupled Receptor Signaling in the Cardiovascular System
October 2022 "Pepducins are small-lipidated peptides designed from the intracellular loops of G protein-coupled
- đ° GPCR Weekly News, June 24 to 30, 2024
Approach Redox-modulated SNX25 as a novel regulator of GPCR-G protein signaling from endosomes Cellular lipids encoding protomers of the 5-HT 2A -mGlu2 receptor complex in living cells GPCRs in Oncology and Immunology Metabolic
- đ° GPCR Weekly News, April 3 to 9, 2023
SUCNR1 signaling in adipocytes controls energy metabolism by modulating circadian clock and leptin expression Methods & Updates in GPCR Research The Road to Quantitative Lipid Biochemistry in Living Cells.
- đ° GPCR Weekly News, January 29 to February 4, 2024
April 22 - 23, 2024 | Endocrine Metabolic GPCRs Join the Endocrine Metabolic GPCRs event in Birmingham signaling mediated by β-arrestins and its potential role in heart failure GPCRs in Neuroscience Role of lipids
- đ° GPCR Weekly News, February 20 to 26, 2023
Impact of membrane lipid polyunsaturation on dopamine D2 receptor ligand binding and signaling GPCR Binders A robust approach for MicroED sample preparation of lipidic cubic phase embedded membrane protein crystals
- Discover the Hottest GPCR News of the Week: Oct 7-13, 2024!
in GPCR Research High-throughput G protein-coupled receptor-based autocrine screening for secondary metabolite Structural basis of Îź-opioid receptor targeting by a nanobody antagonist Probing the energy landscape of the lipid
- đ° GPCR Weekly News, December 18 to 31, 2023
Palmitoylation of the Glucagon-like Peptide-1 Receptor Modulates Cholesterol Interactions at the Receptor-Lipid American Physiology Summit April 5 - 10, 2024 | AACR Annual Meeting April 22 - 23, 2024 | Endocrine Metabolic
- đ° GPCR Weekly News, April 22 to 28, 2024
autism spectrum disorders Systematic characterization of multi-omics landscape between gut microbial metabolites Structural and Molecular Insights into GPCR Function Fungal alkaloid malbrancheamide reorients the lipid
- đ° GPCR Weekly News
resurrection of plant GPCRs Structural and Molecular Insights into GPCR Function Synergistic and Competitive Lipid
- đ° GPCR Weekly News, November 20 to 26, 2023
and Immunology RGS5 maintaining vascular homeostasis is altered by the tumor microenvironment High Metabolite Diversity, and Biological Activity Advances in steroid research from the pioneering neurosteroid concept to metabolomics American Physiology Summit April 5 - 10, 2024 | AACR Annual Meeting April 22 - 23, 2024 | Endocrine Metabolic Schmeizl NEW Scientist NEW Lead Researcher NEW Post-Doctoral Fellow Sr Scientist in Obesity, Muscle, and Metabolism
- Therapeutic validation of an orphan G proteinâcoupled receptor
in various physiological functions, such as sensory perception, reproduction, development, growth, metabolism , and are also linked to major diseases, such as neuroinflammatory, metabolic and autoimmune diseases Some studies have also reported GPR84 involvement in pain, atherosclerosis, and even metabolic disorders IM (3,3â˛âmethylenebisâ1Hâindole) has been identified as a positive allosteric modulator of GPR84, a metabolite
- đ° GPCR Weekly News, May 20 to 26, 2024
prospects, and pathophysiological perspectives Structural and Molecular Insights into GPCR Function Bilayer lipids
- đ° GPCR Weekly News, January 8 to 14, 2024
April 22 - 23, 2024 | Endocrine Metabolic GPCRs Join us at the Endocrine Metabolic GPCRs event on April in Cardiology, Endocrinology, and Taste Propionate functions as a feeding-state-dependent regulatory metabolite
- Inversago Pharma Completes Phase 1 Clinical Trial on First-in-Class, Peripheral CB1 Blocker and...
Phase 1 results and supportive preclinical package assist in the launch of Phase 2 clinical development Metabolic successful completion of the Phase 1 Clinical Trial for its INV-202 molecule that focuses on treating metabolic
- Arginine 125 Is an Essential Residue for the Function of MRAP2
Understanding the mechanism by which MRAP2 regulates G protein-coupled receptors helps in elucidating the metabolic pathways involved in metabolic dysfunction and in developing new drugs as specific targets of the MRAP2
- Glucagon receptor-mediated regulation of gluconeogenic gene transcription is endocytosis-dependent..
is true for the glucagon receptor (GCGR), which mediates physiological regulation of hepatic glucose metabolism Together, these results implicate the endosomal signaling paradigm in metabolic regulation by glucagon
- đ° GPCR Weekly News, April 1 to 7, 2024
GPCR Partnered Events April 22 - 23, 2024 | Endocrine Metabolic GPCRs Join the Endocrine Metabolic GPCRs Muscle Cell Movement Hepatic extracellular ATP/adenosine dynamics in zebrafish models of alcoholic and metabolic
- Novel Therapies for Cardiometabolic Disease: Recent Findings in Studies with Hormone...
One successful strategy is the so-called metabolic surgery whose beneficial effects are beyond dietary , a logical and rational approach is the use of the dual and triagonism of GCPC to achieve complete metabolic
- đ° GPCR Weekly News, March 25 to March 31, 2024
GPCR Partnered Events April 22 - 23, 2024 | Endocrine Metabolic GPCRs Join the Endocrine Metabolic GPCRs biarylamine acting as agonist at human β3 adrenoceptors and exerting BRL37344-like effects on mouse metabolism Adults Confo Therapeutics Secures VLAIO Grant Supporting Drug Discovery & Development In Endocrine And Metabolic
- đ° GPCR Weekly News, February 26 to March 3, 2024
GPCR Partnered Events April 22 - 23, 2024 | Endocrine Metabolic GPCRs Join the Endocrine Metabolic GPCRs in GPCR Research Cryo-electron microscopy for GPCR research and drug discovery in endocrinology and metabolism