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41 items found for "Lung adenocarcinoma"
- Intermolecular Interactions in G Protein-Coupled Receptor Allosteric Sites at the Membrane Interface
We show that besides classical hydrogen bonds, weak polar interactions such as O-HC, O-Br, and long-range
- High GPER expression in triple-negative breast cancer is linked to pro-metastatic pathways and...
heterogeneous disease with few effective targeted therapies and precision therapeutic options over a long
- 📰 GPCR Weekly News, May 1 to 7, 2023
Adrenomedullin 2/intermedin is a slow off-rate, long-acting endogenous agonist of the adrenomedullin2
- Artificial intelligence – faster, smarter, cheaper GPCR drug discovery
Artificial intelligence - Machine learning vs Deep Learning GPCRs have long been recognized as important ability of a ligand to induce or inhibit a cellular response (pEC50 or pIC50, respectively), and how long
- Class B1 GPCR Dimerization: Unveiling Its Role in Receptor Function and Signaling
., Glucagon-Like Peptide-1 and Its Class B G Protein-Coupled Receptors: A Long March to Therapeutic Successes
- 📰 GPCR Weekly News, September 4 to 10, 2023
pyrimidines as Tools to Investigate A3 Adenosine Receptors in Cancer Cell Lines Severity of neurological long-COVID
- 📰 GPCR Weekly News
Research CPGL: Prediction of Compound-Protein Interaction by Integrating Graph Attention Network With Long
- Nanobodies: New Dimensions in GPCR Signaling Research
., Fung, J. J., Pardon, E., Casarosa, P., Chae, P. S., Devree, B. T., Rosenbaum, D. M., Thian, F.
- Unlock the Future of GPCR Science: Breakthroughs and Courses Await | Sep 2 - Sep 8, 2024
pain and chronic inflammation Developmental exposures to common environmental pollutants result in long-term
- Overview of adhesion GPCRs self-activation
Structurally they characterize by a long extracellular region of adhesion-like domains which modulate
- Glyco-sulfo hotspots in the chemokine receptor system
sulfated mCCR2 peptides can outcompete available chemokines, decreasing retinal degradation in mice (Jung
- Unlocking the Therapeutic Potential of Previously Undruggable GPCRs
This leads to strikingly long in vitro receptor occupancy durations (at least seven days), meaning that
- Ode to GPCRs
involved in "short-term memory", whereas cAMP signaling and new protein synthesis are required for "long-term