GPCR Symposia Our upcoming symposium on March 15th is about GPCR activation and signaling. GPCR Partnered Events March 5 - 7, 2024 | 3rd GPCRs - Targeted Drug Discovery Summit Join us at the 3rd GPCRs Summit in Boston on March 5-7, 2024. 13 - 15 | 9th German Pharm-Tox Summit March 23 - 24, 2024 | Ligand Recognition and Molecular Gating Seminar March 24 - 29, 2024 | Ligand Recognition and Molecular Gating Conference April 1 - 4, 2024 |

Let Mark Schmeizl, our Chief Matchmaker help. Contact him by filling out this form. SLAS2024 International Conference and Exhibition NEW February 11 - 14, 2023 | 2024 BPS Annual Meeting March 5 - 7, 2024 | 3rd GPCRs - Targeted Drug Discovery Summit March 23 - 24, 2024 | Ligand Recognition and Molecular Gating Seminar March 24 - 29, 2024 | Ligand Recognition and Molecular Gating Conference April July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs - Contact Mark

Small-molecule targeting of GPCR-independent non-canonical G protein signaling inhibits cancer progression Deadline extended to March 31st, 2023. (February 20 - March 3, 2023). (March 2, 2023) GEM2023. (March 14-17, 2023). SLAS 2023 Building Biology in 3D Symposium.

acid subtype B (GABAB) positive allosteric modulator (PAM) drug candidates has been extended until March include chronic cough, in addition to the rights to develop certain retained compounds for Charcot-Marie-Tooth

Canonical chemokine receptors – scavenging “decoys” Chemokine receptors coordinate cell migration upon The chemokine receptor family comprises 19 canonical chemokine receptors together with 4 atypical chemokine Although less characterized, canonical chemokine receptor systems have been also shown to not only directly CCR2 canonical signaling requires the activation of Gαiβγ, followed by phosphorylation of the receptor But why do canonical chemokine receptors have this dual role in physiology?

February 16 - 21, 2025 | Harnessing the Power of Advanced Multimodal Approaches to GPCR Drug Discovery March 12 - 14, 2025 | NextGen Biomed 2025 March 25 - 28, 2025 | 10th German Pharm-Tox Summit April 1 - 5, Activation and Signaling Pathophysiological significance and modulation of the transient receptor potential canonical

Non-canonical Golgi-compartmentalized Gβγ signaling: mechanisms, functions, and therapeutic targets. Deadline extended to March 31st, 2023 GPCR Events, Meetings, and Webinars 2nd GPCR-Targeted Drug Discovery SLAS2023 International Conference and Exhibition (February 25 - March 1, 2023). 2nd ERNEST Training School (February 20 - March 3, 2023). (March 2, 2023) GEM2023. (March 14-17, 2023). SLAS 2023 B uilding Biology in 3D Symposium.

Leukotriene B4 receptor 2 governs macrophage migration during tissue inflammation From odor to oncology: non-canonical | SLAS2024 International Conference and Exhibition February 11 - 14, 2024 | 2024 BPS Annual Meeting March 5 - 7, 2024 | 3rd GPCRs - Targeted Drug Discovery Summit March 23 - 24, 2024 | Ligand Recognition and Molecular Gating Seminar March 24 - 29, 2024 | Ligand Recognition and Molecular Gating Conference April

pharmacology' Yao Lu and colleagues work on 'Molecular insights into orphan GPCRs relevant to schizophrenia' Carole Scientific Meeting NEW February 3 - 7, 2024 | SLAS2024 International Conference and Exhibition NEW March 23 - 24, 2024 | Ligand Recognition and Molecular Gating Seminar NEW March 24 - 29, 2024 | Ligand Recognition

Mark your calendar for September and October 2024. Dr. Maria Waldhoer, JoAnn Trejo, and Anne Marie Quinn. Did you watch Episode #150 of the Dr. GPCR Matchmaking Mark Schmeizl, our Chief Matchmaker, can help you find your perfect match if you want Contact Mark today to get started. Dr. Mark your calendar for October 23 - 25, 2024, as we kick off the 11th Adhesion GPCR Workshop in Mexico

Mark:  “Beth, why did you decide to join Crinetics?” Mark:  “Have you found this to be accurate?” Beth:  “Yes.  Mark:  “Are there particular assay types of interest?” Mark:  “Beth, why would someone want you as their boss?” By: Mark Schmeizl Chief Matchmaker at Dr. GPCR

Our Chief Matchmaker, Mark Schmeizl, is here to assist you. | SLAS2024 International Conference and Exhibition February 11 - 14, 2023 | 2024 BPS Annual Meeting March 5 - 7, 2024 | 3rd GPCRs - Targeted Drug Discovery Summit March 23 - 24, 2024 | Ligand Recognition and Molecular Gating Seminar March 24 - 29, 2024 | Ligand Recognition and Molecular Gating Conference April

More specifically, this review covers assays to monitor the canonical G protein signaling pathway (e.g recruitment/activation, inositol phosphate accumulation, or Ca2+ mobilization), assays to monitor non-canonical

You can find more information about them on the Live Talks page and mark your calendar HERE. ASCEPT Annual Scientific Meeting February 3 - 7, 2024 | SLAS2024 International Conference and Exhibition March 23 - 24, 2024 | Ligand Recognition and Molecular Gating Seminar March 24 - 29, 2024 | Ligand Recognition

December 2021 " Dame Carol Robinson DBE, FRS, FRSC, FMedSci, Oxford University’s first female Professor

Mark your calendars for the following events: September 22- TOMORROW: Attend this Friday's Dr. ASCEPT Annual Scientific Meeting February 3 - 7, 2024 | SLAS2024 International Conference and Exhibition March 23 - 24, 2024 | Ligand Recognition and Molecular Gating Seminar March 24 - 29, 2024 | Ligand Recognition

Mark your calendars for these important events: September 22: Save the date for the Dr. ASCEPT Annual Scientific Meeting February 3 - 7, 2024 | SLAS2024 International Conference and Exhibition March 23 - 24, 2024 | Ligand Recognition and Molecular Gating Seminar March 24 - 29, 2024 | Ligand Recognition

October 2022 "G protein-coupled receptors (GPCRs) are important drug targets characterized by a canonical

July 21st marks our next Dr. , 2023) Structure, Mechanism, and Drug Interactions of GPCRs, Ion Channels, and Transport Proteins (March

GPCR Symposia Our upcoming symposium on March 15th is about GPCR activation and signaling. GPCR Partnered Events March 5 - 7, 2024 | 3rd GPCRs - Targeted Drug Discovery Summit Join us at the 3rd GPCRs Summit in Boston on March 5-7, 2024. 13 - 15 | 9th German Pharm-Tox Summit March 23 - 24, 2024 | Ligand Recognition and Molecular Gating Seminar March 24 - 29, 2024 | Ligand Recognition and Molecular Gating Conference April 1 - 4, 2024 |

., Caron, M. G., Lefkowitz, R. J., & Strader, C. D. (1986).

October 2022 "The canonical model for G protein-coupled receptors (GPCRs) activation assumes that stimulation

Here, we determine that GRKs phosphorylate a non-canonical substrate, anterior pharynx-defective 1A (

It’s time to mark your calendars and save the dates—let’s make some stellar memories together! February 16 - 21, 2025 | Harnessing the Power of Advanced Multimodal Approaches to GPCR Drug Discovery NEW March 12 - 14, 2025 | NextGen Biomed 2025 NEW March 25 - 28, 2025 | 10th German Pharm-Tox Summit NEW April

Before we dive into the latest news, mark your calendars for July 21st for our next Dr. Structure, Mechanism, and Drug Interactions of GPCRs, Ion Channels, and Transport Proteins (March 24

various cellular processes such as cell proliferation, migration, apoptosis, and transcription via canonical

Mark your calendars for September and October 2024! We are excited to announce that Dr. GPCR Matchmaking Meet Mark Schmeizl, our Chief Matchmaker. Whether you’re hiring top talent or seeking a new career opportunity, Mark’s expertise ensures successful Mark discussed this position with Beth Fleck, Director of In Vitro Pharmacology at Crinetics Pharmaceuticals Mark your calendar for the GPCRs as Therapeutic Targets symposium on October 11th, 2024.

March 2022 "March 3, 2022 Susanna Naggie, MD, and Sudarshan Rajagopal, MD, PhD Two School of Medicine