Search Results
98 items found for "Marcelo G Kazanietz"
- Ep 61 with About Dr. Marta Filizola
Klingenstein-Nathan G. dynamics, and function of important classes of membrane proteins and prominent drug targets, including G
- Neuroimmune interplay during type 2 inflammation: symptoms, mechanisms and therapeutic targets in atopic diseases
polyangiitis , European Medicines Agency , FDA , FcεRIα , FeNO , Fractional exhaled nitric oxide , G-protein-coupled alpha , JAK , JAK inhibitors , JAKi , Janus kinase , MAPK , MCP-4 , MRGPRX1 , Mas-related family of G protein-coupled receptor 11 , Mas-related family of G protein-coupled receptor X1 , Mas-related family of G-protein-coupled receptor 3 , Mas-related family of G-protein-coupled receptors , Mitogen-activated
- Ep 82 with Dr. Lauren M. Slosky
Slosky’s research is focused on understanding how neuropeptide G protein-coupled receptors (GPCRs) regulate Marc G. Caron at Duke University. Dr. These ligands stimulate receptor β-arrestin recruitment without activating canonical G protein signaling
- Olfactory Receptors and Tumorigenesis: Implications for Diagnosis and Targeted Therapy
Targeted Therapy Published date October 4, 2024 Abstract "Olfactory receptors (ORs) are a class of G Authors Yi Tang, Ye Tian, Chun-Xia Zhang, Guo-Tai Wang Tags G Protein-coupled receptors , Olfactory receptors
- GPCR Retreat 2023 | Dr. GPCR Ecosystem
November 2-4, 2023 We are pleased to welcome you at Le Château Montebello , the 22nd Annual Great Lakes G activity-modifying proteins or RAMPs regulate GPCR function, is confirmed as Plenary Speaker of the inaugural Marc G. Additionally, there will be a Marc G.
- Deciphering the genetic landscape of lumpy skin disease: Unraveling variable virulence through comprehensive genome sequence analysis in India
Authors R Mishra, S K Biswas, S Nandi, S Mahajan, K G Sai Balaji, V Gairola, D Poloju, S Gulzar, K P Singh, R K Singh, G K Sharma Tags Genome sequence , Lumpy skin disease , Molecular diversity , Virulence
- Ep 87 with Dr. Bianca Plouffe
Robert Lefkowitz , which led to the finding that both β-arrestin and G protein can simultaneously bind Funded by a Wellcome Trust Seed Award, she investigated biased and compartmentalized G protein signaling
- The pyruvate-GPR31 axis promotes transepithelial dendrite formation in human intestinal dendritic cells
G-protein-coupled receptors (GPCRs) sense metabolites and can act as key mediators that translate gut Eiichi Morii, Seiichi Hirota, Hiroki Ikeuchi, Eiji Umemoto, Atsushi Kumanogoh, Kiyoshi Takeda Tags G
- Involvement of Protease-Activated Receptor2 Pleckstrin Homology Binding Domain in Ovarian Cancer: Expression in Fallopian Tubes and Drug Design
While the involvement of G-protein-coupled receptors (GPCRs) in cancer is growing, GPCR-based therapies Sorina Grisaru-Granovsky , Shunit Armon , Tatyana Rudina , Priyanga Appasamy , Rachel Bar-Shavit Tags G-protein
- The Effect of Cancer-Associated Mutations on Ligand Binding and Receptor Function - A Case for the 5-HT2C Receptor
for the 5-HT2C Receptor Published date October 29, 2024 Abstract "The serotonin 5-HT2C receptor is a G Gorostiola González, Gerard J P van Westen, Erik H J Danen, Laura H Heitman Tags 5-HT(2C) receptor , G
- Comparative Analysis of the GNAI Family Genes in Glioblastoma through Transcriptomics and Single-Cell Technologies
We investigated the prognostic values of the guanine nucleotide-binding protein G(i) alpha subunit (GNAI Sanskriti Dey , Sachin Kumar , Adrian Wangsawijaya Santoso , Bianca Tobias William , Chih-Yang Wang Tags G-protein-coupled
- Ep 47 with Dr Simone Promel Dr Ines Liebscher
on the different modes of action of Adhesion GPCRs and found that they do not only mediate classical G Starting with proving and characterizing G-protein coupling, Ines spends several years studying the activation
- Ep 77 with Martin Audet
the Institute of Pharmacology of Sherbrooke and is an emerging leader in the structural biology of G
- Dr. GPCR Community Presentation | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
research was focused on investigating the cellular effects of missense lung cancer-mutations in the G-protein-coupled
- Ep 156 with Dr. Justin English
developing and innovating technologies to solve broad questions in pharmacology, with a specific focus on G-protein
- Stimulation of ectopically expressed muscarinic receptors induces IFN-γ but suppresses IL-2 production by inhibiting activation of pAKT pathways in primary T cells
Previously, we reported that the G-protein-coupled human muscarinic receptor could bypass tyrosine kinases Here, we demonstrate that stimulating G-protein-coupled muscarinic receptors (M1 and synthetic hM3Dq)
- Neutrophils are itching to specialize
Authors Carlos H Hiroki , Bryan G Yipp Source Contribute to the GPCR News Coming soon Become a Contributor
- GPR56: GPCR as a guardian against ferroptosis
Lin et al. demonstrated that GPR56, a G-protein-coupled receptor, can be activated by its agonist to
- Ep 155 with Endocrine Metabolic GPCR Organizers
Francisco with Professor Mark von Zastrow where she identified novel core cellular machinery critical for G continued to undertake postdoctoral research in Oxford, investigating the signalling and trafficking of the G
- Elucidation of active components and target mechanism in Jinqiancao granules for the treatment of prostatitis and benign prostatic hyperplasia
The characterized compounds were evaluated on four G-protein coupled receptors (GPCRs: GPR35, muscarinic Wanxian Wang, Yumin Yao, Jixia Wang, Yanfang Liu, Xinmiao Liang Tags Benign prostatic hyperplasia , G-protein
- Noval insights and therapeutic strategies for tumor-induced kidney pathologies
Xu et al. identified the mammalian neurokinin 3 receptor (TACR3), a homolog of the G protein-coupled
- Ep 120 with Brendan Wilkins
research assistant at the Victor Chang Cardiac Research Institute where he investigated the orphan G
- Exacerbating effects of single-dose acute ethanol exposure on neuroinflammation and amelioration by GPR110 (ADGRF1) activation
wild type (WT) and knockout (KO) mice at 10-12 weeks of age were given an oral gavage of ethanol (3 g/ kg) or maltose (5.4 g/kg) at 1-4 h prior to the injection of LPS (1 mg/kg, i.p.) followed by the GPR110
- Ep 63 with Dr. Khaled Abdelrahman
Molecular Medicine and Neuroscience at the University of Ottawa as a Postdoctoral Fellow to explore novel G
- Student Flash Presentations | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Its Relevance For Adhesion GPCR Signaling In Vivo Lara-Sophie Brodmerkel Novel isoforms of adhesion G Recent studies implicate the dysregulation of adhesion G-Protein coupled receptors (GPCRs) in GBM development For Adhesion GPCR Signaling In Vivo Lara-Sophie Brodmerkel Abstract "Over the last years, Adhesion G genomic datasets for markers of active chromatin and new transcript variants in the ADGRB1 (adhesion G Authors & Affiliations "Gandhi, Riya; Chandan, Nancy; Kwarcinski, Frank; Smrcka, Alan; and Tall, Gregory G.
- Emerging GPCR targets for AUD: Insights from preclinical studies
Emerging GPCR targets for AUD: Insights from preclinical studies Published date July 5, 2024 Abstract "G
- Ep 85 with Nicholas Holliday
University of Nottingham in 2006, where he is now Associate Professor, establishing a lab focused on G
- Session III | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
NTF Release Sensor Approach for Drug Discovery for Human Adhesion GPCRs Stephanie Häfner Abstract "G Protein-coupled receptors (GPCRs) are common drug targets, yet no approved drugs exist for the Adhesion G Salinas "I am currently part of a dynamic research team dedicated to advancing the understanding of G