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78 items found for "Miles Thompson"
- Regulation of pulmonary surfactant by the adhesion GPCR GPR116/ADGRF5 requires a tethered agonist...
mouse expressing a non-cleavable GPR116 mutant phenocopies the pulmonary phenotype of GPR116 knock-out mice
- 📰 GPCR Weekly News, January 16 to 22, 2023
GPCR Activation and Signaling Cornichon protein CNIH4 is not essential for mice gametogenesis and fertility Cannabinoid tolerance in S426A/S430A x beta-arrestin 2 knock-out double mutant mice.
- Coincident Regulation of PLCβ Signaling by Gq-Coupled and μOpioid Receptors Opposes Opioid- Mediated
Finally, inhibition of Gq-GPCR coupling in mice enhanced the antinociceptive effects of morphine.
- TRPM3 in the eye and in the nervous system - from new findings to novel mechanisms
TRPM3's best understood function is its role as a peripheral noxious heat sensor in mice.
- CCL25/CCR9 interaction promotes the malignant behavior of salivary adenoid cystic carcinoma via...
effect of CCL25 on the development of SACC in vivo was examined by a xenograft tumor model in nude mice
- Identification and functional characterization of the sulfakinin and sulfakinin receptor in the...
The expression levels of the two genes were different between male and female adults, and there were
- Serotonin Receptor 5-HT2A Regulates TrkB Receptor Function in Heteroreceptor Complexes
In adult mice, intraperitoneal ketanserin injection increased basal TrkB phosphorylation in the frontal
- GPCR Therapeutics welcomes Dr. Ed Brennan as their new Vice President, Head of Clinical Development
He has led teams that have filed more than 10 Investigational New Drug Applications (IND), as well as
- 📰 GPCR Weekly News, July 31 to August 6, 2023
and Pina M Cardarelli's research: Burixafor Hydrobromide (GPC-100) effects on hematopoietic cells in mice Novel C-X-C Chemokine Receptor 4 Antagonist and Mobilizer of Hematopoietic Stem/Progenitor Cells, in Mice
- Successful prednisolone or calcimimetic treatment of acquired hypocalciuric hypercalcemia caused...
characteristics with the 2 cases we previously reported as follows: (a) elderly (74-87 years at diagnosis), (b) male
- Pharmacological targeting of cGAS/STING-YAP axis suppresses pathological angiogenesis and...
protein (YAP) signaling in endothelial cells, which was evidenced by the attenuation of organ fibrosis in mice
- GASP1 enhances malignant phenotypes of breast cancer cells and decreases their response to...
inhibition of cell proliferation, colony formation, migration, invasion and xenograft tumor growth in nude mice
- Opposite Effects of Src Family Kinases on YAP and ERK Activation in Pancreatic Cancer Cells...
formation by PDAC cells and suppessed the growth of MiaPaCa-2 cells xenografted into the flank of nude mice
- β-arrestin1 promotes tauopathy by transducing GPCR signaling, disrupting microtubules and autophagy
ARRB1 alleviates tauopathy and rescues impaired synaptic plasticity and cognitive impairments in PS19 mice
- Chemogenetic stimulation of the G i pathway in astrocytes suppresses neuroinflammation
characterized by decreased levels of proinflammatory cytokines, glial activation, and cognitive impairment in mice
- Lack of Oestrogen Receptor Expression in Breast Cancer Cells Does Not Correlate with Kisspeptin...
MDA-MB-231 cells are metastatic when implanted in mice while BT-20 are not and remain epithelial-like
- 📰 GPCR Weekly News, March 27 to April 4, 2023
Cannabinoid Tolerance in S426A/S430A x β-Arrestin 2 Knockout Double-Mutant Mice. Deficiency of G protein-coupled receptor Gpr111/Adgrf2 causes enamel hypomineralization in mice by alteration Financial Year ended 31 December 2022 Addex Raises $5.0 Million in Equity Financing Testing the limits of SMILES-based
- 📰 GPCR Weekly News
with an N-terminal D-lysine, impairs growth of patient-derived xenografts of colorectal carcinoma in mice
- Activation of GPR183 by 7 α,25-Dihydroxycholesterol Induces Behavioral Hypersensitivity through...
have characterized the molecular mechanisms underpinning 7α,25-OHC/GPR183-induced hypersensitivity in mice
- Decoding β-Arrestins: from Structure to function
Knockout studies in mice suggest that β-arrestin isoforms possess some level of functional redundancy , as depleting one isoform results leads to relatively mild effects (Conner, D.
- β2-Adrenergic Receptor Expression and Intracellular Signaling in B Cells Are Highly Dynamic during..
collagen-induced arthritis (CIA) were investigated to provide an explanation of why only B cells from arthritic mice
- 📰 GPCR Weekly News, July 3 to 9, 2023
mesenchymal stromal cell secretory factor SDF-1-mediated improvement of islet function in non-obese diabetic mice
- 📰 GPCR Weekly News, July 10 to 16, 2023
(OGR1) deficiency exacerbates crystal deposition and kidney injury in oxalate nephropathy in female mice
- Lysophosphatidic Acid and Several Neurotransmitters Converge on Rho-Kinase 2 Signaling to Manage...
recordings were performed in hypoglossal MNs (HMNs) obtained from adult and neonatal rats, neonatal knockout mice
- 📰 GPCR Weekly News, May 15 to 21, 2023
, activates mas-related G protein-coupled receptor C11 (MrgprC11) to induce scratching behaviors in mice
- Synaptic integration of subquantal neurotransmission by co-localized G protein coupled receptors in
We demonstrate in male and female rats that GABAB receptors receptors alter Pr, whereas 5-HT1B receptors
- The mouse cytomegalovirus G protein-coupled receptor homolog, M33, coordinates key features of ...
In the context of MCMV latency, spleen explants from M33ΔC38-infected mice were markedly attenuated for
- 📰 GPCR Weekly News, June 3 to June 9, 2024
RNA-seq screening and gene function analysis uncover GPR183 as a key mediator for methionine to stimulate milk