GPCR Activation and Signaling Cornichon protein CNIH4 is not essential for mice gametogenesis and fertility Cannabinoid tolerance in S426A/S430A x beta-arrestin 2 knock-out double mutant mice.

Finally, inhibition of Gq-GPCR coupling in mice enhanced the antinociceptive effects of morphine.

TRPM3's best understood function is its role as a peripheral noxious heat sensor in mice.

effect of CCL25 on the development of SACC in vivo was examined by a xenograft tumor model in nude mice

The expression levels of the two genes were different between male and female adults, and there were

In adult mice, intraperitoneal ketanserin injection increased basal TrkB phosphorylation in the frontal

He has led teams that have filed more than 10 Investigational New Drug Applications (IND), as well as

and Pina M Cardarelli's research: Burixafor Hydrobromide (GPC-100) effects on hematopoietic cells in mice Novel C-X-C Chemokine Receptor 4 Antagonist and Mobilizer of Hematopoietic Stem/Progenitor Cells, in Mice

characteristics with the 2 cases we previously reported as follows: (a) elderly (74-87 years at diagnosis), (b) male

protein (YAP) signaling in endothelial cells, which was evidenced by the attenuation of organ fibrosis in mice

inhibition of cell proliferation, colony formation, migration, invasion and xenograft tumor growth in nude mice

formation by PDAC cells and suppessed the growth of MiaPaCa-2 cells xenografted into the flank of nude mice

ARRB1 alleviates tauopathy and rescues impaired synaptic plasticity and cognitive impairments in PS19 mice

characterized by decreased levels of proinflammatory cytokines, glial activation, and cognitive impairment in mice

MDA-MB-231 cells are metastatic when implanted in mice while BT-20 are not and remain epithelial-like

Cannabinoid Tolerance in S426A/S430A x β-Arrestin 2 Knockout Double-Mutant Mice. Deficiency of G protein-coupled receptor Gpr111/Adgrf2 causes enamel hypomineralization in mice by alteration Financial Year ended 31 December 2022 Addex Raises $5.0 Million in Equity Financing Testing the limits of SMILES-based

with an N-terminal D-lysine, impairs growth of patient-derived xenografts of colorectal carcinoma in mice

have characterized the molecular mechanisms underpinning 7α,25-OHC/GPR183-induced hypersensitivity in mice

collagen-induced arthritis (CIA) were investigated to provide an explanation of why only B cells from arthritic mice

Knockout studies in mice suggest that β-arrestin isoforms possess some level of functional redundancy , as depleting one isoform results leads to relatively mild effects (Conner, D.

mesenchymal stromal cell secretory factor SDF-1-mediated improvement of islet function in non-obese diabetic mice

recordings were performed in hypoglossal MNs (HMNs) obtained from adult and neonatal rats, neonatal knockout mice

(OGR1) deficiency exacerbates crystal deposition and kidney injury in oxalate nephropathy in female mice

, activates mas-related G protein-coupled receptor C11 (MrgprC11) to induce scratching behaviors in mice

We demonstrate in male and female rats that GABAB receptors receptors alter Pr, whereas 5-HT1B receptors

In the context of MCMV latency, spleen explants from M33ΔC38-infected mice were markedly attenuated for

RNA-seq screening and gene function analysis uncover GPR183 as a key mediator for methionine to stimulate milk

Oncology and Immunology A GPCR checkpoint drives CD8+ T cell dysfunction and immunotherapy failure in mice