placentation, uteroplacental malperfusion, oxidative stress, endoplasmic reticulum stress, dysregulated immune tolerance

of molecular tools to study GPCR trafficking in real-time opens new avenues for understanding drug tolerance

Activation in Class A GPCRs Ligand binding in the orthosteric site leads to diverse activation mechanisms

Cannabinoid tolerance in S426A/S430A x beta-arrestin 2 knock-out double mutant mice.

of a human cell surface protein in yeast cells Trevena Reports Favorable TRV045 Topline Safety and Tolerability

Multi-omics integration analysis of GPCRs in pan-cancer to uncover inter-omics relationships and potential

Mutations in Sensitive Regions of Regulators of G Protein Signaling Predicted by Three-Dimensional Missense Tolerance

Transient interaction with the receptor catalyzes β-arrestin activation, including β-arrestin inter-domain

Cannabinoid Tolerance in S426A/S430A x β-Arrestin 2 Knockout Double-Mutant Mice.

Updates in GPCR Research Highly efficient GPCR immobilization with enhanced fouling resistance, salt tolerance

Patching holes in the mechanism of opioid tolerance.