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45 items found for "POTS"
- Functional Assessment of Cancer-Linked Mutations in Sensitive Regions of Regulators of G Protein Signaling Predicted by Three-Dimensional Missense Tolerance Ratio Analysis
cause phenotypic changes that negatively impact GPCR-G protein signaling and suggests that 3DMTR is a potentially
- Opposite Effects of Src Family Kinases on YAP and ERK Activation in Pancreatic Cancer Cells: Implications for Targeted Therapy
Previously, we identified potent positive crosstalk between insulin/IGF-1 receptors and G protein-coupled A combination of dasatinib and trametinib potently and synergistically inhibited colony formation by
- Dr. GPCR Summit 2021 Live Talks
September 15, 2021 at 6:00:00 PM Learn More >> Hydroxycarboxylic acid receptor 3 and GPR84 signaling with potential
- The power of many: Multilevel targeting of representative chemokine and metabolite GPCRs in personalized cancer therapy
culminates by illuminating emerging therapies and discussing innovative strategies to harness the full potential
- Ep 147 with Dr. Demet Araç
Symposium to his team and encourage his students, postdocs, and PhD students to contact Yamina for potential addressed the naming conventions of proteins in the field, with Yamina expressing concern about the potential They also discussed the importance of the extracellular region of these receptors and its potential as upcoming Doctor GPCR Symposium in June, for which Demet is the first confirmed speaker, and discussed potential the future, with Yamina expressing her intention to reach out to Demet's students and postdocs for potential
- SSTR2 positively associates with EGFR and predicts poor prognosis in nasopharyngeal carcinoma
light on the intricate relationship between SSTR2 and EGFR in NPC and provides new insights into the potential Additionally, SSTR2 has potential as a new biomarker for poor prognosis in NPC patients."
- Ep 71 with Dr. Jean Martin Beaulieu
how cell surface express proteins can act as allosteric modulators of D2R signaling and explores the potential identification of an RNA binding protein (FXR1P) involved in the regulation of protein synthesis as a potential
- Spliceosome mutations are associated with clinical response in a phase 1b/2 study of the PLK1 inhibitor onvansertib in combination with decitabine in relapsed or refractory acute myeloid leukemia
PLK1 inhibition with ONV in combination with DAC could be a potential therapy in R/R AML patients, particularly
- Dopamine-Mediated Motor Recovery after Ischemic Stroke
currently developing the translational component of our research to capitalize on the druggability potential More specifically, we investigate the druggability potential of new signaling partners we identified
- Ep 153 with Dr Jacek Mokrosiński
discussed the importance of building professional connections and strategies for introducing oneself to potential
- Chemokine N-terminal-derived peptides differentially regulate signaling by the receptors CCR1 and CCR5
These 3 to 10-residue peptides displayed weak potency but, surprisingly, retained their signaling on
- Ep 66 with Dr. Antony A. Boucard Jr
that they are highly polymorphic proteins expressed as various alternatively spliced isoforms thus potentially
- Ep 146 with Dr Michael Feigin
discussed his work on G-protein coupled receptors (GPCRs) in breast cancer, identifying GPR161 as a potential They also touched upon the potential of GPCR modulation in stimulating the immune system to fight cancer The conversation highlighted the complexities and challenges of drug prescription and the potential for He highlighted the importance of re-evaluating one's work and its potential implications. Towards the end, Yamina asked about job opportunities in Mike's lab, to which Mike responded that potential
- Ep 06 with Dr. J. Silvio Gutkind
Silvio Gutkind highlights how his past experience proves useful in current COVID times and potential
- Ep 53 with Dr. Timo De Groof
research tools, to investigate different GPCR conformations, while also focusing on their therapeutic potential
- Ep 83 with Dr. Jean-Philippe Pin
including biosensors, cryo-EM, photoswitchable ligands, and nanobodies as pharmacological tools and potential
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