Search Results
56 items found for "Pan-cancer"
- GPR56 signaling pathway network and its dynamics in the mesenchymal transition of glioblastoma
multifunctional adhesion GPCR involved in diverse biological processes ranging from development to cancer Despite its important role in cancer, its mechanism of action or signaling is not completely understood
- Session II | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Avila Zozaya "My doctoral research was focused on investigating the cellular effects of missense lung cancer-mutations Sciences, University of Alabama at Birmingham (UAB), Birmingham, Alabama, USA 5 O'Neal Comprehensive Cancer Van Meir pursued postdoctoral work at the Ludwig Institute for Cancer Research in San Diego and joined Van Meir has developed novel therapeutic approaches for cancer using oncolytic adenoviruses and anti-angiogenic translate these novel agents to testing in clinical trials with the hope to develop novel medicines for cancer
- Comparative Analysis of the GNAI Family Genes in Glioblastoma through Transcriptomics and Single-Cell Technologies
Published date October 23, 2023 Abstract Glioblastoma multiforme (GBM) is one of the most aggressive cancers We used The Cancer Genome Atlas (TCGA) GBM genomic dataset to identify differentially expressed genes
- Dr. GPCR Community Presentation | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Avila Zozaya "My doctoral research was focused on investigating the cellular effects of missense lung cancer-mutations
- Ep 135 with Dr. Katarzyna Marcinkiewicz
Weill Cornell Graduate School of Medical Sciences in New York City, studying epigenetic changes in cancer
- Expression pattern and clinical significance of beta 2-adrenergic receptor in oral squamous cell carcinoma: an emerging prognostic indicator and future therapeutic target
However, the role of β2-AR in oral cancer is not well identified. Kumar Mohanty, Rajender Singh, Vijay Kumar, Uma Shankar Singh, Rakesh Kumar Singh Tags GPCR; OSCC; Oral cancer
- Session III | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Sabbagh undertook post-doctoral fellowships at the Ontario Cancer Institute and the University of Toronto projects aimed on drug discovery of small molecules for the treatment of inflammatory disorders and cancer Department of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer (IRIC the development of innovative treatments for a range of diseases, including psychiatric disorders and cancer
- Ep 157 with Dr. Nagarajan Vaidehi
She is also the Associate Director of the City of Hope Comprehensive Cancer Center. Dr.
- Session IX / Technology capsule: Light on aGPCR signaling and function | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
His research experience includes phylogenetics and cancer epigenetics.
- GPR68-ATF4 signaling is a novel prosurvival pathway in glioblastoma activated by acidic extracellular microenvironment
Lorazepam, which has off target agonism of GPR68, is linked to worse clinical outcomes for a variety of cancers However, the role of tumor microenvironment acidification in GPR68 activation has not been assessed in cancer
- Ep 92 with Dr. Stephane Angers
development of novel antibody molecules blocking and activating the Wnt pathway for the treatment of cancers
- "Have a nice weekend, and I'll see you tomorrow!": RAMP-interacting GPCR Pathways
Caron on the web UNC-Chapel Hill Department of Cell Biology and Physiology UNC Lineberger Comprehensive Cancer
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- Dynamic Phosphoproteomics of BRS3 Activation Reveals the Hippo Signaling Pathway for Cell Migration
The lung cancer cell line H1299-BRS3 was treated with MK-5046, an agonist of BRS3, for different durations
- Unveiling Non-Canonical Functions for Gαq Signaling Pathways
(GRK2), a known regulator of Gq-GPCR signaling in HNSCC tumor progression (International Journal of Cancer
- Distinct sub-cellular signal propagation as a component of functional selectivity
of Biochemistry and Molecular Medicine and the CEO of the Institute for Research in Immunology and Cancer
- GPCR Courses
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- Gallein, G protein βγ subunits inhibitor, suppresses the TGF-α-induced migration of hepatocellular carcinoma cells via inhibition of the c-Jun N-terminal kinase
Small molecules targeting the subunits of Gα and Gβγ have been developed as cancer therapeutics.
- Ep 72 with Dr. Stuart Maudsley
At the MRC he developed novel prostate cancer therapeutics based upon his research into GPCR pluridimensional
- Ep 78 with Dr. Stuart Maudsley
At the MRC he developed novel prostate cancer therapeutics based upon his research into GPCR pluridimensional
- Ep 151 with Dr GPCR Board
control cell signaling by protease-activated receptors (PARs) and the impact on vascular inflammation and cancer research has focused on PAR1, which has important functions in hemostasis, thrombosis, inflammation, and cancer
- GPCR Retreat Schedule 2023
November 3rd / 3:00 PM Coffee Break 4 Read More Friday, November 3rd / 3:30 PM G Proteins and GPCRs in Cancer 3rd / 3:55 PM Inhibition of Relaxin Autocrine Signaling Confers Therapeutic Vulnerability in Ovarian Cancer
- Session IV | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
of Medicine, where he studies BAI1's role in the brain and the radiobiology of treatments for brain cancer
- Ep 107 with Dr. Roger Sunahara
speculate that these aberrations in Galpha-s(l), specifically, may be involved in other pathologies such as cancer
- Full Agenda for Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Adhesion GPCR Signaling In Vivo Caroline Formstone Interrogating The Role Of CELSR1 (ADGRC1) In Breast Cancer thermogenesis during prolonged cold exposure Jesse Stillwell Next Generation MBD2 inhibitors for Brain Cancer
- Ep 150 with Dr GPCR Team
During that time, I investigated the effect of lung cancer-related mutations in the GAIN domain of the
- Dr. GPCR Summit 2021 Live Talks
Kooistra, Gaspar Pandy-Szekeres September 13, 2021 at 2:00:00 PM Learn More >> CXCR4 heteromers as novel cancer
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