Search Results
62 items found for "Pei Ling Chia"
- Itaconate in host inflammation and defense
Authors Dan Ye , Pu Wang , Lei-Lei Chen , Kun-Liang Guan , Yue Xiong Tags IRG1/ACOD1 , cancer , inflammatory
- Ep 136 with Murat Tunaboylu & Ben Holland
pursued international strategic partnerships, managed IP matters, helped establish a manufacturing line
- Increased protease-activated receptor 1 autoantibodies are associated with severe COVID-19
Hoyer , Andreas Glück , Martina Guggeis , Alexander Ossysek , Andre Küller , Derk Frank , Christoph Lange
- Autocrine proteinase-activated receptor signaling in PC3 prostate cancer cells
In this study, we examined the androgen-independent human prostatic cancer cell line PC3 and find the
- Ep 53 with Dr. Timo De Groof
Timo hopes to combine his previous GPCR experience with his current focus to set up his own research line
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- CCL5-producing migratory dendritic cells guide CCR5+ monocytes into the draining lymph nodes
, we observed that both CD88hiCD26lomonocytes and CD88-CD26hi cDCs captured inhaled antigens in the lung Authors Kavita Rawat , Anita Tewari , Xin Li , Arlind B Mara , William T King , Sophie L Gibbings , Chinaza
- miR-19a may function as a biomarker of oral squamous cell carcinoma (OSCC) by regulating the signaling pathway of miR-19a/GRK6/GPCRs/PKC in a Chinese population
Authors Jijun Chen , Liang Wang , Danhua Ma , He Zhang , Jiayan Fan , Hongyan Gao , Xinyu Xia , Wei Wu
- Dynamic Phosphoproteomics of BRS3 Activation Reveals the Hippo Signaling Pathway for Cell Migration
The lung cancer cell line H1299-BRS3 was treated with MK-5046, an agonist of BRS3, for different durations
- Unveiling G-protein coupled receptors as potential targets for ovarian cancer nanomedicines: from RNA sequencing data analysis to in vitro validation
Subsequently, primary ovarian cancer cells derived from ascites and ovarian cancer cell lines were used
- Activation of orphan receptor GPR132 induces cell differentiation in acute myeloid leukemia
Notably, GPR132 activation by 8GL promoted differentiation and reduced colony formation in human AML cell lines Authors Chunyang Yi, Jiacheng He, Dan Huang, Yumiao Zhao, Chan Zhang, Xiyun Ye, Ying Huang, Ruth Nussinov
- GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis
in multiple cancers, and quantitative proteomic and RNA profiling of exosomes in human cancer cell lines
- The EBI2 receptor is coexpressed with CCR5 in CD4+ T cells and boosts HIV-1 R5 replication
Cell lines expressing EBI2 were established by transduction with HIV vectors.
- Neurotoxicity and accumulation of CPPD quinone at environmentally relevant concentrations in Caenorhabditis elegans
Authors Xin Wan, Geyu Liang, Dayong Wang Tags Accumulation , C. elegans , CPPDQ , Neurotoxicity Source
- Deletion of macrophage Gpr101 disrupts their phenotype and function dysregulating host immune responses in sterile and infectious inflammation
endogenous role of this pro-resolving receptor in modulating macrophage biology using a novel mouse line This was linked with an increased inflammatory response in the Gpr101 deficient animals and a reduced These observations were linked with a marked dysregulation in peritoneal lipid mediator concentrations
- From outside to inside and back again: the lysophosphatidic acid-CCN axis in signal transduction
group previously reported that LPA induces production of CCN1 protein in human prostate cancer cell lines
- Simultaneous activation of CXC chemokine receptor 4 and histamine receptor H1 enhances calcium signaling and cancer cell migration
Here, we show that HRH1 is widely expressed in various cancer cell lines and cancer tissues and that
- CircFKBP5 Suppresses Apoptosis and Inflammation and Promotes Osteogenic Differentiation
Authors Cuiwei Liang , Wenmiao Li , Qian Huang , Qitao Wen .
- Vasoactive intestinal peptide receptor 2 signaling promotes breast cancer cell proliferation by enhancing the ERK pathway
this study, we found that VIPR2 overexpression in MCF-7 and MDA-MB-231 cells, human breast cancer cell lines
- Lactate receptor GPR81 drives breast cancer growth and invasiveness through regulation of ECM properties and Notch ligand DLL4
Key findings were additionally studied in other breast cancer cell lines and in mammary epithelial cells
- Prediction of survival and immunotherapy response by the combined classifier of G protein-coupled receptors and tumor microenvironment in melanoma
, Qiangcheng Wang , Lu Wang , Yang Yang , Min Ren , Yanlin Li , Zixu Gao , Shaoluan Zheng , Yiteng Ding
- Identification of a G-protein coupled receptor-related gene signature through bioinformatics analysis to construct a risk model for ovarian cancer prognosis
The levels of GPCRRGs were examined in normal and OV cell lines using quantitative reverse-Etranscription
- Stimulation of ectopically expressed muscarinic receptors induces IFN-γ but suppresses IL-2 production by inhibiting activation of pAKT pathways in primary T cells
Authors Trang T T Nguyen , Wen Lu , Wandi S Zhu , K Mark Ansel , Hong-Erh Liang , Arthur Weiss .
- GPR37 expression as a prognostic marker in gliomas: a bioinformatics-based analysis
protein-coupled receptor (GPCR) that is implicated in different physiological pathways in the brain, and has been linked expression was significantly higher in the glioma tissues compared to the normal brain tissues, and was linked Authors Kairong Liang , Zhaoxiong Guo , Shizhen Zhang , Danmin Chen , Renheng Zou , Yuhao Weng , Chengxiang
- Ep 155 with Endocrine Metabolic GPCR Organizers
She received her BSc in Human Biology from King’s College London in 1997, and while her Ph.D. commenced
- Removing the GPCR-mediated brake on exocytosis enhances insulin action, promotes adipocyte browning, and protects against diet-induced obesity
Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN 37232, USA 4 Peking University, China Lange and Annie Mary Lyle Chair in Cardiovascular Research, and Professor of Pharmacology, Ophthalmology
- Session IV | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
I then moved to King's College London, where my interest and passion for kinases in brain health and
- Dr. GPCR Summit 2021 | Dr. GPCR Ecosystem
Imagine binge-watching your favorite talk over and over whenever you want to during the Summit.