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47 items found for "Pro-inflammatory macrophages"
- Ep 53 with Dr. Timo De Groof
Argen X and gained experience in the identification and characterization of llama-derived antibodies in inflammatory
- Orphan receptor GPR50 attenuates inflammation and insulin signaling in 3T3-L1 preadipocytes
These data suggest that GPR50 can attenuate inflammatory levels and regulate insulin signaling in adipocytes
- Ep 110 with Dr. G. Aditya Kumar
In addition, he explored the role of the host membrane in the entry of intracellular pathogens into macrophages
- Severity of neurological long-COVID symptoms correlates with increased level of autoantibodies targeting vasoregulatory and autonomic nervous system receptors
Importantly, the overall inflammatory state was low in all 3 groups.
- Metabolic crosstalk: Extracellular ATP and the tumor microenvironment in cancer progression and therapy
functions as a mighty damage-linked molecular pattern when released outside the cell, accumulating in inflammatory
- C5aR2 receptor: The genomic twin of the flamboyant C5aR1
compared to the C5aR1, which has received enormous attention for its role in both acute and chronic inflammatory
- CircFKBP5 Suppresses Apoptosis and Inflammation and Promotes Osteogenic Differentiation
Inflammation was analysed by measuring the release of inflammatory cytokines.
- Session III | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Sabbagh was recruited by Vertex Pharmaceuticals (Canada) where he worked on biomarker discovery for inflammatory Sabbagh led research projects aimed on drug discovery of small molecules for the treatment of inflammatory
- GPR176 promotes fibroblast-to-myofibroblast transition in organ fibrosis progression
fibroblasts abundantly expressed Gpr176 compared to alveolar epithelial cells, endothelial cells, and macrophages
- Coronavirus Porcine Epidemic Diarrhea Virus Utilizes Chemokine Interleukin-8 to Facilitate Viral Replication by Regulating Ca2+ Flux
The chemokine interleukin-8 (CXCL8/IL-8) is indispensable for the activation and trafficking of inflammatory
- Unbiased multitissue transcriptomic analysis reveals complex neuroendocrine regulatory networks mediated by spinal cord injury-induced immunodeficiency
Akap8, Gfer, Cxcl10, Tnfaip3, Icam1, Fcgr2b, Ager, Dusp10, and Mapkapk2) were significantly enriched in inflammatory
- Ep 67 with Dr. Graham Ladds
He continued to work at Warwick as a post-doc studying pro-hormone convertases before securing a 5-year
- Neuroimmune interplay during type 2 inflammation: symptoms, mechanisms and therapeutic targets in atopic diseases
the neuroimmune interactions that underlie the various sensory and autonomic pathologies in type 2 inflammatory
- GPR68-ATF4 signaling is a novel prosurvival pathway in glioblastoma activated by acidic extracellular microenvironment
A defining hallmark of GBM is a highly acidic tumor microenvironment, which is thought to activate pro-tumorigenic Conclusion: These results indicate GPR68 emerges as a critical sensor for an autocrine pro-tumorigenic
- Dr. GPCR Summit 2021 Live Talks
>> Engineering a human GPCR to create self-tunable engineered yeast probiotics for the treatment of inflammatory
- GPR37 promotes colorectal cancer against ferroptosis by reprogramming lipid metabolism via p38-SCD1 axis
Our results reveal the pro-carcinogenic effect of GPR37 in primary CRC and suggest that targeting GPR37
- Dr. GPCR Summit 2021 | Dr. GPCR Ecosystem
Pros: You can polish your recording to your satisfaction. Pros: It may take less time to prepare for the presentation Cons: You may make mistakes since it's a
- Ultrasensitive dose-response for asbestos cancer risk implied by new inflammation-mutation model
., by doing so for GPCR-mediated signal transduction by one or more endogenous autacoid specialized pro-resolving
- Combinatorial depletions of G-protein coupled receptor kinases in immune cells identify pleiotropic and cell type-specific functions
wide range of GPCR ligands, whereas combinatorial GRK depletions in other immune cell types lead to pro