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106 items found for "Shane Wright"
- 📰 GPCR Weekly News, January 1 to 7, 2024
Officer Rhythm Pharmaceuticals and LG Chem Life Sciences Enter Agreement for Rhythm to Acquire Global Rights
- Hop in the Time Machine with GPCR: Unraveling the Future of Research! ⦿ Nov 24 - Dec 1, 2024
News from November 25th to December 1st, 2024 Industry News Amgen says obesity drug caused up to 20% weight
- Addex Raises $10 Million In Equity Financing
a healthcare-focused institutional investor, pursuant to which the Company agreed to sell 3,752,202 shares in the form of 625,367 American Depositary Shares (“ADSs”) at a gross purchase price of $6.50 per ADS , which is equivalent to CHF 1.00 per share. Each ADS represents six shares. the “Unregistered Warrants”), as well as unregistered pre-funded warrants to purchase up to 5,478,570 shares
- Embark on a GPCR Adventure: Your Weekly Research Expedition! | Oct 21-27, 2024
Let’s keep fostering a collaborative environment for sharing ideas and expanding knowledge! The presentations and discussions sparked new ideas and collaborations, shaping the future of the field
- Addex raises $4.2 million in equity financing
in the form of 550,000 American Depositary Shares (“ADSs”) at a gross purchase price of $1.70 per ADS , which is equivalent to CHF 0.27 per share. Each ADS represents six shares. agreed to issue to Armistice Capital unregistered pre-funded warrants to purchase up to 11,700,000 shares $1.69 with $0.01 payable on exercise as well as unregistered warrants to purchase up to 15,000,000 shares
- Crinetics Pharmaceuticals Announces Pricing Of Underwritten Common Stock Offering
endocrine-related tumors, announced today the pricing of an underwritten follow-on offering of 5,625,563 shares of its common stock at a price to the public of $22.22 per share. All of the shares to be sold in the offering are to be sold by Crinetics.
- 📰 GPCR Weekly News, July 31 to August 6, 2023
Randy Hall's study: GPR37L1's role in shaping cortical astrocytes during development Dr. Want to share your project informally? Submit a 1-minute abstract video using this form.
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GPCR Summit from October 10th to the 16th is taking shape.
- Dr. Ross Bathgate becomes Scientific co-founder of LASEREDD Therapeutics
July 2022 "I’m happy to share that I’m starting a new position as Scientific co-founder LASEREDD Therapeutics
- Unlocking the Therapeutic Potential of Previously Undruggable GPCRs
The natural ligand of the target receptor provides an excellent scaffold, already with a size and shape Right: Orion ligand analogs are engineered to optimize transmembrane domain providing significantly increased Orion’s PROcisionXᵀᴹ Platform In Orion’s discovery process, shape space at the TM domain ‘message’ site Since shape space exploration is specifically focused on the ‘message’ site in the TM domain, this means
- Amgen to Acquire Chemocentryx for $4 Billion in Cash
companies have entered into a definitive agreement under which Amgen will acquire ChemoCentryx for $52 per share
- Production of human A2AAR in lipid nanodiscs for 19F-NMR and single-molecule fluorescence...
We explain in detail steps shared between the two sample preparation strategies, including expression
- Dr. Nicola J. Smith - Dr. GPCR Podcast
Please share! https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ #gpcr #drgpcr #podcast
- Production of human A2AAR in lipid nanodiscs for 19F-NMR and single-molecule fluorescence...
We explain in detail steps shared between the two sample preparation strategies, including expression
- Structural dynamics of Smoothened (SMO) in ciliary membrane and its interaction with membrane lipids
in the ciliary membrane, and to gain molecular-level insights into the role of the primary cilia in shaping reveals the movements of TM5, TM6, and TM7, linked with the helix8, which are possibly involved in shaping
- Dr. JoAnn Trejo - Dr. GPCR Podcast
Sharing how she became a scientist, educator, mentor, and the powerhouse we know today.
- 📰 GPCR Weekly News - January 2 to 8, 2023
Hello Readers👋, We're excited to share our weekly newsletter with you. Sherwin Sells 30,000 Shares STALICLA signs agreement with Novartis on neurodevelopmental disorders Call
- AlphaFold2 versus experimental structures: evaluation on G protein-coupled receptors
different in many aspects including the assembly of the extracellular and transmembrane domains, the shape
- 📰 GPCR Weekly News, April 1 to 7, 2024
We're excited to share our coverage of the latest developments in GPCRs for this week. We also ask that you share this with your eligible colleagues.
- Multifunctional role of GPCR signaling in epithelial tube formation
formation requires Rho1-dependent actomyosin contractility to generate the cellular forces that drive cell shape
- GPCRs steer G i and G s selectivity via TM5-TM6 switches as revealed by structures of serotonin...
We find that the macro-switch by the TM5-TM6 length is shared by class A GPCR-G protein structures.
- Multifunctional role of GPCR signaling in epithelial tube formation
formation requires Rho1-dependent actomyosin contractility to generate the cellular forces that drive cell shape
- Job Opportunity Spotlight #1: Principal Scientist, In Vitro Pharmacology
Our conversation provided additional insight you cannot find in a job description, so I thought I’d share
- TM5-TM6: structural switches that modulate the coupling of serotonin receptors to Gs or Gi
Prior to this report we did not know how different serotonin receptor subtypes which share high sequence Interestingly, in the case of promiscuous receptors they found that these receptors shared conserved
- OMass Therapeutics's founder, Carol Robinson, has been awarded the prestigious Louis-Jeantet ...
Her work in the field has been instrumental and is set to shape the future of drug discovery for years
- 📰 GPCR Weekly News, July 24 to July 30, 2023
Want to share your work in an informal setting? We'll be sharing the list of our confirmed speakers soon!
- 📰 GPCR Weekly News, February 5 to 11, 2024
We will also have a poster session in breakout rooms on Zoom; if you are interested in sharing your work You'll share your contributor articles with the community, stay updated with GPCR literature, network
- Profiling Immune Cell and Platelet Transcriptomes
As the field continues to evolve, the insights gained from this research will be instrumental in shaping