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130 items found for "Shunda Du"
- 📰 GPCR Weekly News, February 12 to 18, 2024
Nayara Braga Emidio, Ross Cheloha, Laura M Wingler, et al. for their work on Nanobody-Mediated Dualsteric strength of an allosteric effect as agonist's efficacy GPCR Binders, Drugs, and more Nanobody-Mediated Dualsteric GPCR-neuropeptide axis dampens hyperactive neutrophils by promoting an alternative-like polarization during
- 📰 GPCR Weekly News, January 15 to 21, 2024
Due to popular demand, we have opened additional spots. If you'd like to join colleagues and Dr. Classified GPCR News from January 15th to 21st, 2024 Adhesion GPCRs The adhesion GPCR GPR116/ADGRF5 has a dual
- 📰 GPCR Weekly News, December 18 to 31, 2023
families in gastropods Unraveling the G protein-coupled receptor superfamily in aphids: Contractions and duplications
- Chemokine receptor-targeted drug discovery: progress and challenges
forward to target CKRs especially in cancer, nevertheless, targeting this system is a challenging task due
- 📰 GPCR Weekly News, December 11 to 17, 2023
We'll pause our regular updates during this time and will resume our newsletter in the upcoming year signaling pathways GPCRs in Oncology and Immunology Leukotriene B4 receptor 2 governs macrophage migration during
- 📰 GPCR Weekly News, November 13 to 19, 2023
an E3 ubiquitin ligase adaptor for substrate linear polyubiquitination GPCR Binders, Drugs, and more Dual
- 📰 GPCR Weekly News, October 30 to November 4, 2023
Sosei Heptares Announces Submission of New Drug Application in Japan for Daridorexant (ACT-541468), a Dual
- Targeting Intracellular Allosteric Sites in GPCRs
For this reason, GPCRs have been a focus of drug development for decades due to their role in regulating
- 📰 GPCR Weekly News, October 9 to 15, 2023
low relatedness Industry News Nobel Laureates Highlight Symposium Celebrating Lefkowitz’s 50 Years at Duke
- 📰 GPCR Weekly News, October 2 to 8, 2023
Development DKK 25 million to development of databases supporting medical research ‘Define your own success’: Duke
- 📰 GPCR Weekly News, September 25 to October 1, 2023
selectivity and allosteric probe dependence at Hydroxycarboxylic acid receptor HCAR2 Antipsychotic displays dual Lefkowitz's Career at Duke October 3, 2023, | FREE Seminar: Changing paradigm on Therapeutics targeting
- 📰 GPCR Weekly News, September 18 to 24, 2023
in Cardiology, Endocrinology, and Taste Structural and functional analysis of salivary intercalated duct Lefkowitz's Career at Duke October 3, 2023, | FREE Seminar: Changing paradigm on Therapeutics targeting
- Nanobodies: New Dimensions in GPCR Signaling Research
., Dukkipati, A., Feinberg, E. N., Angelini, A., Waghray, D., Dror, R. O., Ploegh, H.
- 📰 GPCR Weekly News, September 11 to 17, 2023
Robert Lefkowitz on his 50 years at Duke. Congratulations. Dr. basis of GPR84 signaling Structural diversity of leukotriene G-protein coupled receptors Industry News Duke Lefkowitz's Career at Duke October 3, 2023, | FREE Seminar: Changing paradigm on Therapeutics targeting
- 📰 GPCR Weekly News, September 4 to 10, 2023
Emerging Cannabinoid Analogs GPCRs in Neuroscience Serotonin signaling regulates actomyosin contractility during
- 📰 GPCR Weekly News, August 21 to 27, 2023
Immunology Chemokine Cxcl1-Cxcl2 heterodimer is a potent neutrophil chemoattractant Neuroimmune interplay during
- Decoding β-Arrestins: from Structure to function
signaling predominantly occurs at the plasma membrane, certain receptors retain their active conformation during Consequently, understanding dynamic interactions between effectors during trafficking becomes crucial elusive, and certain effector proteins with overlapping sites may experience mutually exclusive binding due M. et al. 1999), while dual knockout is lethal (Schmid, C. L., & Bohn, L. M. 2009).
- 📰 GPCR Weekly News, July 31 to August 6, 2023
Randy Hall's study: GPR37L1's role in shaping cortical astrocytes during development Dr. activating GHS-R1a/D2R heterodimers GPR37L1 controls maturation and organization of cortical astrocytes during
- 📰 GPCR Weekly News, July 24 to July 30, 2023
Adhesion GPCRs Dual role of the adhesion G-protein coupled receptor ADRGE5/CD97 in glioblastoma invasion
- 📰 GPCR Weekly News, July 3 to 9, 2023
Structural and Molecular Insights into GPCR Function Dual mechanisms of cholesterol-GPCR interactions
- Structural landscape of the Chemokine Receptor system
adopting a hook-like conformation, whereas the chemokine antagonist ([5P7]CCL5) folds into a helical shape due precise molecular signature responsible for G-protein activation by CCR1 remains unknown, primarily due
- 📰 GPCR Weekly News, May 22 to 28, 2023
Differential Responses of the GLP-1 and GLP-2 Receptors to N-Terminal Modification of a Dual Agonist.
- Unlocking Cell's Secrets: Spontaneous β-Arrestin-Membrane Preassociation Drives Receptor-Activation
This event extends the duration of β-arrestin at the plasma membrane, enabling it to independently reach
- 📰 GPCR Weekly News, May 8 to 14, 2023
Pharmaceuticals Announces Positive Phase 3 Results Showing Mavorixafor Reduced the Rate, Severity, and Duration
- 📰 GPCR Weekly News, April 24 to 30, 2023
Single-cell transcriptome analysis of NEUROG3+ cells during pancreatic endocrine differentiation with Biotechnology will be participating in a panel discussion at the LSX World Congress Novel living yeast-based dual
- VAMP2: a crucial player in the delivery of MOR to the synapse
However, the selectivity of SNARE complex proteins to regulate the release of different types of GPCRs during
- 📰 GPCR Weekly News, April 3 to 9, 2023
GPR37L1 controls maturation and organization of cortical astrocytes during development.
- Feeder or trigger – CCR2 as a scavenger and regulator of cell migration
CCR2 is an example of a dual-function receptor that directly regulates both cell migration and scavenging But why do canonical chemokine receptors have this dual role in physiology? How balanced is this dual role?