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80 items found for "Timm H Westhoff"
- ShouTi Introduces Basecamp Bio as a Wholly Owned Subsidiary to Expand Pipeline and Partnerships
March 2022 "February 17, 2022 08:00 AM Eastern Standard Time SAN FRANCISCO & SHANGHAI- ShouTi Inc.,
- Illuminating the draggable GPCR-ome
This time with none other than Dr. Bryan Roth There are 10 open tickets available. Get yours now!
- Ginsenoside Rg5 allosterically interacts with P2RY12 and ameliorates deep venous thrombosis by...
DVT formation is a time-dependent inflammatory process in which NETosis plays an important role.
- Tectonic Therapeutic Strengthens Leadership Team
July 2022 "July 19, 2022 07:00 AM Eastern Daylight Time BOSTON-- Tectonic Therapeutic , Inc. a pre-clinical
- Activation of GPR183 by 7 α,25-Dihydroxycholesterol Induces Behavioral Hypersensitivity through...
In rodents, intrathecal injection of its ligand, 7α,25-dihydroxycholesterol (7α,25-OHC), causes time-dependent Non-biased transcriptomic analyses of dorsal-horn spinal cord (DH-SC) tissues harvested at the time of
- Expression pattern and clinical significance of beta 2-adrenergic receptor in oral squamous cell...
Methods: Immunohistochemistry, western blot and quantitative real-time PCR techniques were used to analyze
- GPR110, a receptor for synaptamide, expressed in osteoclasts negatively regulates osteoclastogenesis
In this study, we found, for the first time, that the expression of GPR110 increased during osteoclastogenesis
- Design Pharmaceuticals Closes $5 Million Pre-series A Round to Accelerate Commercialization of ...
Commercialization of Ultrahigh Throughput Drug Discovery Platform " April 12, 2022 07:00 AM Eastern Daylight Time
- Dopamine activates astrocytes in prefrontal cortex via α1-adrenergic receptors
Instead, fast calcium signals in PFC astrocytes are time locked to dopamine release and are mediated
- Adhesion GPCR Consortium Newsletter - May 2024
This was because, at that time, the neurexins, another family of adhesion molecules that also happened diversity among the aGPCR community, added to the fact that this will all take place for the first time There are a lot of firsts in this perspective: the first time in a LATAM country, the first organized
- New Resources in GPCRdb
This time, the GPCRdb team ( Dr. David Gloriam , Dr.
- Drug Discovery Picks Up the Pace, Stays on Target
January 2022 "Voltaire argued, “Perfection is attained by slow degrees; it requires the hand of time
- Conservation of Allosteric Ligand Binding Sites in G-Protein Coupled Receptors
We then mapped the 394 GPCR X-ray structures available at the time of the analysis (September 2020).
- Propranolol: A “Pick and Roll” Team Player in Benign Tumors and Cancer Therapies
In 2008 (and for the first time in the clinic), the therapeutic benefits of the β-adrenergic receptor
- 📰 GPCR Weekly News, March 11 to 17, 2024
M Papasergi-Scott, Peter Gmeiner, Brian K Kobilka, Georgios Skiniotis, et al. for their research on Time-resolved transport of nascent G protein-coupled receptors Structural and Molecular Insights into GPCR Function Time-resolved
- Identification of A2BAR as a potential target in colorectal cancer using novel fluorescent GPCR...
As well, fluorescent ligands were effective at monitoring real-time A2BAR receptor labeling using live-imaging
- A2B Adenosine Receptor Enhances Chemoresistance of Glioblastoma Stem-Like Cells under Hypoxia: New..
Here, we show for the first time that MRP3 expression is induced under hypoxia through the A2B adenosine
- 📰 GPCR Weekly News, November 13 to 19, 2023
For those who joined any of our symposium sessions, we kindly request a moment of your time to fill out – our premium members have continuous access to revisit and watch the archived presentations at any time
- Luciferase-based GloSensor™ cAMP assay: Temperature optimization and application to cell-based kinet
The GloSensor™ cAMP assay enables real-time monitoring of signaling downstream of many GPCRs.
- Dynamic recognition of naloxone, morphine and endomorphin1 in the same pocket of µ-opioid receptors
Molecular dynamics (MD) simulations on a 1-μs time scale and metadynamics-enhanced conformational sampling
- 📰 GPCR Weekly News, December 11 to 17, 2023
We'll pause our regular updates during this time and will resume our newsletter in the upcoming year Gastric Inhibitory Polypeptide Receptor (GIPR) Revealed by Trapped-Ion-Mobility Spectrometry Coupled to Time-of-Flight Mass Spectrometry (TIMS-TOF MS) A rapid, tag-free way to purify functional GPCRs tANCHOR fast and cost-effective
- 📰 GPCR Weekly News, October 30 to November 4, 2023
Hannes Schihada and his lab team developed fluorescent analogues for real-time binding studies of orphan primary cultures of osteoblasts and osteoclasts Development of Fluorescent AF64394 Analogues Enables Real-Time
- Unlock the Future of GPCR Science: Breakthroughs and Courses Await | Sep 2 - Sep 8, 2024
Topics: New cellular assays, real-time kinetics, and unique GPCR behaviors. 🔥 Why You Should Enroll But act fast – this offer is only available for a limited time. Not a premium member yet?
- Coordinated transcriptomics and peptidomics of central nervous system identify neuropeptides and ...
expression patterns of these 98 genes in various larval tissues were evaluated using quantitative real-time
- GPCRS: AN ODYSSEY FROM STRUCTURE, SIGNALING AND REGULATION TO THERAPEUTICS
This timely meeting will not only provide an inclusive forum for communication, but also a platform for
- GPCR Updates: Celebrating Breakthroughs, New Course Launches Soon, and Exclusive Discounts! | Aug 26 - Sep 1, 2024
Delve into new cellular assays, real-time kinetics, and unique GPCR behaviors. 🔥 Why You Should Enroll Premium members can enjoy a 25% OFF early bird discount , but hurry - it's only available for a limited time
- β2-Adrenergic Receptor Expression and Intracellular Signaling in B Cells Are Highly Dynamic during..
signal-regulated kinase 1/2 (ERK1/2) and cAMP response element-binding protein (CREB)) were analyzed at different time
- 📰 GPCR Weekly News, June 10 to 16, 2024
cardiac drug development GPCRs in Neuroscience Astrocytic PAR1 and mGluR2/3 control synaptic glutamate time