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195 items found for "Tumor-associated macrophages"
- 📰 GPCR Weekly News, September 18 to 24, 2023
under suboptimal conditions Exploiting frequent and specific expression of PRL3 in pediatric solid tumors NEW Scientist (level I or II) NEW Research Fellow Research Technician II - Surgery Post-Doc Research Associate Research Technician Senior Research Associate, In Vitro Pharmacology - Crinetics Pharmaceuticals Postdoc
- 📰 GPCR Weekly News, September 11 to 17, 2023
of survival and immunotherapy response by the combined classifier of G protein-coupled receptors and tumor , 2024 | Chemotactic Cytokines GPCR Jobs NEW Research Technician II - Surgery NEW Post-Doc Research Associate NEW Research Technician Senior Research Associate, In Vitro Pharmacology - Crinetics Pharmaceuticals
- 📰 GPCR Weekly News, November 20 to 26, 2023
Biological Assays GPCRs in Oncology and Immunology RGS5 maintaining vascular homeostasis is altered by the tumor Post-Doctoral Fellow Sr Scientist in Obesity, Muscle, and Metabolism Post-Doctoral Fellow Research Associate I, Tissue Culture Post-Doc Research Associate Postdoctoral Fellow Explore Dr.
- Chemokine receptor-targeted drug discovery: progress and challenges
diseases (Proudfoot 2002), and in recent years attention has increasingly focused on cancer, where tumors chemokine system to provide growth and survival signals, establish and maintain an immunosuppressive tumor Redundancy can be exemplified by the tumor infiltration of Treg cells which can be driven directly by
- An overview of the compartmentalized GPCR Signaling: Relevance and Implications
In the endosomes, sustained G protein signaling has been associated with prolonged interactions between Therefore, targeting specific intracellular compartments and signaling pathways associated with GPCRs Overall, the pharmaceutical challenges associated with tagging GPCRs expressed in cellular compartments Mechanisms Associated with Activation of Intracellular Metabotropic Glutamate Receptor, mGluR5. GPCRomics: GPCR Expression in Cancer Cells and Tumors Identifies New, Potential Biomarkers and Therapeutic
- Neurotransmitters: Potential Targets in Glioblastoma
September 2022 "For decades, glioblastoma multiforme (GBM), a type of the most lethal brain tumor, has
- Enhancing GPCR Research Outreach | Dr GPCR University early-bird registration ends soon!
GPCRs in Oncology and Immunology G protein-coupled receptor-mediated signaling of immunomodulation in tumor position Senior or Lead Researcher Senior Scientist, Cryo-Electron Microscopy Postdoctoral Research Associate
- Dimerization of GPCRs: Novel insight into the role of FLNA and SSAs regulating SST2 and SST5...
Somatostatin receptors (SSTs) are class A GPCRs abundantly expressed in pituitary tumors where they represent somatostatin receptor type 2 (SST2) and 5 (SST5) and regulates their expression and signaling in pituitary tumoral
- Crinetics Pharmaceuticals Expands Executive Team With Appointment Of James Hassard As Chief ...
development, and commercialization of novel therapeutics for rare endocrine diseases and endocrine-related tumors
- The expression and clinical significance of GPR39 in colon cancer
Materials: In our study, we compared GPR39 expression between colon cancers and tumor-adjacent tissues
- Crinetics Pharmaceuticals Announces Pricing Of Underwritten Common Stock Offering
development and commercialization of novel therapeutics for rare endocrine diseases and endocrine-related tumors
- All Aboard the GPCR Express: Your Weekly Update is here! Oct 14-20, 2024
GPCR Jobs Scientist I Cell Biology - Tectonic Therapeutic Senior Scientist, GPCR Pharmacology Research Associate Convergent substitutions and recurrent gene loss in sauropsids Noval insights and therapeutic strategies for tumor-induced
- 📰 GPCR Weekly News, December 11 to 17, 2023
shining light on signaling pathways GPCRs in Oncology and Immunology Leukotriene B4 receptor 2 governs macrophage Postdoctoral Scholar - O’Neill Lab NEW Junior Research Scientist Postdoctoral Fellow Post-Doc Research Associate Assistant/Associate Professor Principal scientist – oncology biomarker expert Postdoctoral Fellow Scientific
- Unlock the Future of GPCR Science: Breakthroughs and Courses Await | Sep 2 - Sep 8, 2024
12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology GPCR Jobs HIGHLIGHT Research Associate hypothalamic-pituitary axis in mice GPCRs in Oncology and Immunology A disturbed metabolite-GPCR axis is associated with microbial dysbiosis in IBD patients: Potential role of GPR109A in macrophages Structural and Molecular
- The Bile Acid Membrane Receptor TGR5 in Cancer: Friend or Foe?
In this review, we discuss both the ‘friend’ and ‘foe’ features of TGR5 by summarizing its tumor-suppressing
- Crinetics Pharmaceuticals announced the formation of an independently operated new company...
development, and commercialization of novel therapeutics for rare endocrine diseases and endocrine-related tumors
- GPCR Buzz of the Week | Sep 23 - 29, 2024
12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology GPCR Jobs HIGHLIGHT Research Associate disease GPCRs in Oncology and Immunology Aberrant hormone receptors regulate a wide spectrum of endocrine tumors
- 📰 GPCR Weekly News, April 1 to 7, 2024
conformations determine signaling through the μ opioid receptor GPCR Binders, Drugs, and more Predicting associations metabolic steatotic liver disease GPCRs in Oncology and Immunology Chemoattractant receptor signaling in humoral Workshop July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs Senior Associate Research Technologies Novo Nordisk Scientist I - Global Research Technologies Novo Nordisk Postdoctoral Associate
- 📰 GPCR Weekly News, January 15 to 21, 2024
death by 72% as first-line treatment for patients with advanced gastroenteropancreatic neuroendocrine tumors Researcher in Structural Biology Post-Doctoral Fellow Postdoctoral Fellow Research Laboratory Specialist Associate
- High GPER expression in triple-negative breast cancer is linked to pro-metastatic pathways and...
the worse survival in patients with lymph node metastasis, TNM stage III as well as nuclear grade G3 tumors
- 📰 GPCR Weekly News, July 3 to 9, 2023
First Patient Enrolled in Phase 1/2 “ELUCIDATE” Trial Assessing GTAEXS617 in Advanced Solid Tumours A Transport Proteins (March 24 - 29, 2024) GPCR Jobs NEW Postdoctoral Fellow, Caron Lab NEW Clinical Trial Associate Research Scientist/Senior Scientist I - Molecular Pharmacology Vice President, Medical Affairs Associate
- CD28 and chemokine receptors: Signalling amplifiers at the immunological synapse
September 2022 "T cells are master regulators of the immune response tuning, among others, B cells, macrophages
- Odorant G protein-coupled receptors as potential therapeutic targets for adult diffuse gliomas ...
Glioma is the most common adult malignant brain tumor and requires novel therapeutic strategies to improve
- Computational study of the conformational ensemble of CX3C chemokine receptor 1 (CX3CR1) and its...
participate in the activation, chemotaxis and recruitment of multiple immunological cells such as microglia, macrophages
- Lack of Oestrogen Receptor Expression in Breast Cancer Cells Does Not Correlate with Kisspeptin...
In KISS1R overexpressing triple-negative breast cancer (TNBC) cells, stimulation has been associated investigation and may enable further stratification of the ability of kisspeptin to influence breast tumour
- Naggie and Rajagopal Elected Members of American Society for Clinical Investigation
They will be officially inducted at a joint meeting of ASCI, the Association of American Physicians ( AAP), and the American Physician-Scientists Association (APSA) on April 8, 2022
- 📰 GPCR Weekly News, April 3 to 9, 2023
Local 5-HT signaling bi-directionally regulates the coincidence time window for associative learning. Vesicle-associated membrane protein 2 is a cargo-selective v-SNARE for a subset of GPCRs. GPCR Events, Meetings, and Webinars NEW AACR 2023 - American Association for Cancer Research (April 14 Convergent Research - Senior Scientist, Cell-Based Assay Development Post Doctoral Fellow Research associate in protein production Vice President, Oncology Clinical Research PostDoctoral Associate PostDoctoral
- 📰 GPCR Weekly News, May 20 to 26, 2024
and Human Kidneys GPCR Activation and Signaling Differential regulation of G protein-coupled receptor-associated pharmacology NEW Senior Scientist - Receptor Pharmacology NEW PostDoctoral Scientist Senior Research Associate /Associate Scientist, Protein Science Post-Doctoral Fellow—Pharmacology/Cell Biology/Biochemistry Post Doctoral Fellow Postdoc Position Senior Associate Scientist - Global Research Technologies Novo Nordisk