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58 items found for "Wenyang Wang"
- Spliceosome mutations are associated with clinical response in a phase 1b/2 study of the PLK1 inhibitor onvansertib in combination with decitabine in relapsed or refractory acute myeloid leukemia
Authors Peter J P Croucher , Maya Ridinger , Pamela S Becker , Tara L Lin , Sandra L Silberman , Eunice S Wang
- Systems Pharmacodynamic Model of Combination Gemcitabine and Trabectedin in Pancreatic Cancer Cells. Part II: Cell Cycle, DNA Damage Response, and Apoptosis Pathways
Authors Xin Miao , Gilbert Koch , Shichen Shen , Xue Wang , Jun Li , Xiaomeng Shen , Jun Qu , Robert
- Identification of S1PR4 as an immune modulator for favorable prognosis in HNSCC through machine learning
Authors Chenshen Huang , Fengshuo Zhu , Hao Zhang , Ning Wang , Qi Huang Tags Cancer , Machine learning
- Activation of PI3K/Akt pathway by G protein-coupled receptor 37 promotes resistance to cisplatin-induced apoptosis in non-small cell lung cancer
Authors Han Liu , Yingjie Zhu , Huikun Niu , Jing Jie , Shucheng Hua , Xiaoxue Bai , Shuai Wang , Lei
- Interplay between G protein-coupled receptors and nanotechnology
Authors Yuhong Jiang , Yuke Li , Xiujuan Fu , Yue Wu , Rujing Wang , Mengnan Zhao , Canquan Mao , Sanjun
- Exploration of prognostic and treatment markers in hepatocellular carcinoma via GPCR-related genes analysis
Authors Yuxin Wang , Bao Jin , Xiangan Wu , Jiali Xing , Baoluhe Zhang , Xiaokun Chen , Xiao Liu , Xueshuai Wan , Shunda Du Tags GPCR ; HCC ; Prognosis ; Systemic treatment Source Contribute to the GPCR News
- Regulator of G protein signaling protein 6 alleviates acute lung injury by inhibiting inflammation and promoting cell self-renewal in mice
Authors Juan Song , Miao Li , Cuicui Chen , Jian Zhou , Linlin Wang , Yu Yan , Jun She , Lin Tong , Yuanlin
- Ep 44 with Dr. Steven Foord
He introduced molecular pharmacology to a wide range of the company's GPCR projects and was able to initiate
- Session VI | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Authors & Affiliations "Groff, Karenna; Donaldson, Hayley; Anderson, Sebastian; Pitti, Kiran; Wang, Shuai
- Ep 30 with Dr. Elva Zhao
run in the mountains, play with Tilly (a 9-year old retired greyhound), collecting mini shoes, and hang
- Ep 61 with About Dr. Marta Filizola
end, her lab uses several computational structural biology tools and rational drug design approaches, ranging
- Increased protease-activated receptor 1 autoantibodies are associated with severe COVID-19
Hoyer , Andreas Glück , Martina Guggeis , Alexander Ossysek , Andre Küller , Derk Frank , Christoph Lange
- Ep 33 with Dr. David E. Gloriam
identified physiological hormones of such under characterized ‘orphan’ receptors and functional probes for a range
- G protein coupled receptor transcripts in human immune cells and platelets
On average, the white cells studied expressed 160 receptor mRNAs (range, 123-206).
- CCR6 as a Potential Target for Therapeutic Antibodies for the Treatment of Inflammatory Diseases
Abstract " The CC chemokine receptor 6 (CCR6) is a G protein-coupled receptor (GPCR) involved in a wide range
- Chemoattractant receptor signaling in humoral immunity
sites on the receptor C termini, which dictates functional outcomes of β-arrestin-mediated signaling, ranging
- GPR4 in the pH-dependent migration of melanoma cells in the tumor microenvironment
Migration of GPR4 overexpressing SK-Mel-28 cells was enhanced in a range of pH 6.5 - pH 7.5 as compared
- CCR7 acts as both a sensor and a sink for CCL19 to coordinate collective leukocyte migration
We further show that these self-generated gradients can sustain the long-range guidance of DCs, adapt
- Expression prevalence and dynamics of GPCR somatostatin receptors 2 and 3 as cancer biomarkers beyond NET: a paired immunohistochemistry approach
A 12-point immunoreactive scoring (IRS) range was used for interpretation of the staining results.
- Principles of Pharmacology in Drug Discovery I
of how pharmacology can greatly extend the ability to predict a candidate's therapeutic value in a range
- GPR56 signaling pathway network and its dynamics in the mesenchymal transition of glioblastoma
receptor 56 (GPR56/ADGRG1) is a multifunctional adhesion GPCR involved in diverse biological processes ranging
- GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis
demonstrate its ability to promote cancer cell motility. " Authors Yu Jin Lee , Kyeong Jin Shin , Hyun-Jun Jang Jin-Sun Ryu , Chae Young Lee , Jong Hyuk Yoon , Jeong Kon Seo , Sabin Park , Semin Lee , A Reum Je , Yang
- NPFF stimulates human ovarian cancer cell invasion by upregulating MMP-9 via ERK1/2 signaling
Authors Ze Wu , Qiongqiong Jia , Boqun Liu , Lanlan Fang , Peter C K Leung , Jung-Chien Cheng Tags Invasion
- Deciphering a GPCR-lncRNA-miRNA Nexus: Identification of an Aberrant Therapeutic Target in Ovarian Cancer
Kashyap , Kar-Ming Fung , Chao Xu , Resham Bhattacharya , Priyabrata Mukherjee , Ciro Isidoro , Yong Sang
- G protein-coupled receptors: A target for microbial metabolites and a mechanistic link to microbiome-immune-brain interactions
gut microbiota act as ligands for specific human G protein-coupled receptors (GPCRs) and modulate a range
- Wnt pathway inhibition with the porcupine inhibitor LGK974 decreases trabecular bone but not fibrosis in a murine model with fibrotic bone
Authors Hsuan Lung, Kelly L Wentworth, Tania Moody, Ariane Zamarioli, Apsara Ram, Gauri Ganesh, Misun Kang
- Combinatorial depletions of G-protein coupled receptor kinases in immune cells identify pleiotropic and cell type-specific functions
Neutrophils lacking all four GRK family members show increased chemotactic migration responses to a wide range
- Removing the GPCR-mediated brake on exocytosis enhances insulin action, promotes adipocyte browning, and protects against diet-induced obesity
Lange and Annie Mary Lyle Chair in Cardiovascular Research, and Professor of Pharmacology, Ophthalmology
