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86 items found for "Young Chan Chae"
- Ep 37 with Dr. Samuel Hoare
I very much enjoyed chatting with Sam about his love for GPCRs, kinetics, and decorticate the complexities
- Ep 31 with Dr. Kevin Pfleger
I sat down with Kevin to chat about GPCRs, pharmacology, and his contributions to the field in both the
- Noval insights and therapeutic strategies for tumor-induced kidney pathologies
Authors Meng Wang, Yong Han, Chao Zhang Source Contribute to the GPCR News Coming soon Become a Contributor
- Ep 146 with Dr Michael Feigin
He shared that his interest in science originated from a young age and his desire to gain more knowledge on projects they are passionate about, emphasizing that ownership and full investment in a project can Yamina asked about job opportunities in Mike's lab, to which Mike responded that potential candidates can
- A2aR on lung adenocarcinoma cells: A novel target for cancer therapy via recruiting and regulating tumor-associated macrophages
Notably, the M2 polarization of TAMs can also be prevented by inhibiting A2aR in vitro. Authors Ying Bai , Xin Zhang , Jiawei Zhou , Jianqiang Guo , Yafeng Liu , Chao Liang , Wenyang Wang ,
- GPCR signaling contributes to immune characteristics of microenvironment and process of EBV-induced lymphomagenesis
Authors Jie Xiong , Yu-Ting Dai , Wen-Fang Wang , Hao Zhang , Chao-Fu Wang , Tong Yin , Shu Cheng , Hui-Juan Zhong , Shan-He Yu , Lu Jiang , Sheng-Yue Wang , Hai Fang , Rui-Hong Zhang , Yue Zhu , Hong-Mei Yi , Xu-Feng Jiang , Jia-Yi Chen , Li Wang , Peng-Peng Xu , Sai-Juan Chen , Wei-Li Zhao Tags CCR1 , Epstein-Barr
- Deciphering a GPCR-lncRNA-miRNA Nexus: Identification of an Aberrant Therapeutic Target in Ovarian Cancer
Nadhan , Rohini Gomathinayagam , Muralidharan Jayaraman , Mingda Yan , Srishti Kashyap , Kar-Ming Fung , Chao Xu , Resham Bhattacharya , Priyabrata Mukherjee , Ciro Isidoro , Yong Sang Song , Danny N Dhanasekaran
- Ep 107 with Dr. Roger Sunahara
structural work on the GPCR-G protein complexes have also revealed some unprecedented conformational changes Some of these changes are associated with G protein activation while the functional consequences of other structural changes remain elusive. have been heavily engaged in studies to address the functional role of these dramatic conformational changes
- Colorectal cancer incidence trends in Golestan, Iran: An age-period-cohort analysis 2004-2018
We calculated the estimated annual percentage change (EAPC) with 95 % confidence intervals (95 % CI) increasing trends in CRC incidence rates from 2004 to 2018 (EAPC = 3.7; 95%CI: 0.4, 7.1), with the greatest changes Conclusion: The increasing trends in CRC rates in Golestan are largely driven by generational changes
- High Metabolite Concentrations in Portal Venous Blood as a Possible Mechanism for Microbiota Effects on the Immune System, and Western Diseases
Diseases Published date November 20, 2023 Abstract "We show that the gut bacterial metabolites, short chain Quanbo Wang , Charles R Mackay Tags Gut microbiota , Western lifestyle diseases , portal vein , short chain
- Legal Policies and Disclaimers | Dr. GPCR Ecosystem
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- Travel Tips for Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
It can include breakfasts. 2. Hotel Exe Suites Reforma 3. Fares are subject to change. Information from public transportation can be followed through Google Maps or City Mapper apps. SIM CARD AND WIFI SIM cards can be easily purchased at the airport and Oxxo stores around the city. We will try to accommodate you as best we can.
- Regulator of G protein signaling protein 6 alleviates acute lung injury by inhibiting inflammation and promoting cell self-renewal in mice
HE staining, ELISA, and immunohistochemistry were used to evaluate pathological changes and the degree vitro, qRT‒PCR, immunofluorescence staining, and western blotting were used to determine the dynamic changes Compared with the control group, we found higher mortality, more pronounced body weight changes, more Authors Juan Song , Miao Li , Cuicui Chen , Jian Zhou , Linlin Wang , Yu Yan , Jun She , Lin Tong , Yuanlin
- Affiliate Policy | Dr. GPCR Ecosystem
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- Esophageal and gastric cancer incidence trends in Golestan, Iran: An age-period-cohort analysis 2004 to 2018
The estimated annual percentage change (EAPC) with 95% confidence interval (95% CI) were calculated. The marked declines in EC incidence rates in Golestan relate to generational changes in its underlying
- Proteogenomic landscape and clinical characterization of GH-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors
ATP2A2 and ARID5B correlated with the GH change rate in the octreotide loading test, and WWC3, SERINC1 , and ZFAND3 correlated with the tumor volume change rate after somatostatin analog treatment.
- Unbiased multitissue transcriptomic analysis reveals complex neuroendocrine regulatory networks mediated by spinal cord injury-induced immunodeficiency
and objectives: The concentrations of adrenocorticotropic hormone and cortisol in plasma, as well as changes pathways related to inhibitory Gi-mediated G protein-coupled receptor (Gi-GPCR) neurons and neuropeptide changes genes: Ciart, per2, per3, cry1, and cry2) were enriched in cortisol secretion and circadian rhythm changes
- Ep 135 with Dr. Katarzyna Marcinkiewicz
Ph.D. from Weill Cornell Graduate School of Medical Sciences in New York City, studying epigenetic changes
- Ep 06 with Dr. J. Silvio Gutkind
highlights how his past experience proves useful in current COVID times and potential benefits the changes in work environments can do for future collaborations.
- Ep 120 with Brendan Wilkins
Since then, Brendan worked as a research assistant at the Victor Chang Cardiac Research Institute where
- Functional Assessment of Cancer-Linked Mutations in Sensitive Regions of Regulators of G Protein Signaling Predicted by Three-Dimensional Missense Tolerance Ratio Analysis
Subsequent permutation analysis can define the protein regions that are most significantly intolerant downstream cAMP measurement, tolerant RGS14-D137Y and RGS10-S64T and intolerant RGS10-K89M resulted in change that 3DMTR identified intolerant residues that overlap with cancer-linked mutations cause phenotypic changes We found that 3DMTR more accurately classifies loss-of-function mutations in RGS proteins than other
- Abstract Submission Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
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- Itaconate in host inflammation and defense
and defense Published date March 5, 2024 Abstract "Immune cells undergo rapid and extensive metabolic changes In addition to contributing to energetic and biosynthetic demands, metabolites can also function as signaling Authors Dan Ye , Pu Wang , Lei-Lei Chen , Kun-Liang Guan , Yue Xiong Tags IRG1/ACOD1 , cancer , inflammatory
- A journey from Duke to McGill along the dopamine circuit
Abstract Coming Soon About Bruno Giros "Bruno Giros' lab is dedicated to investigating how molecular changes
- The binding mechanism of an anti-multiple myeloma antibody to the human GPRC5D homodimer
Here, we present the structure of GPRC5D in complex with a preclinical-stage single-chain antibody (scFv
- Comparative analysis of the occupancy of Histone H3 Lysine 4 methylation in the cells treated with TGFβ and Interferonγ
signalling, it would be of utmost importance to find out the regions undergoing histone modification changes Further analysis of these genes can reveal fascinating insights into epigenetic regulation by growth
- Content and Conduct Policy | Dr. GPCR Ecosystem
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- Applying Pharmacology to Drug Discovery
to give the registrant a good overall understanding of the unique science of pharmacology and how it can Every participant will also get the chance to have a 1:1 meeting with Dr.