As part of the degree, she undertook a 1-year research-based placement at the Charles Perkins Centre Outside the lab, she enjoys baking and swimming and has recently taken up paddle boarding.

these purposes only with third parties whose privacy policies are consistent with ours or who agree to abide and third-party cookies (such as the DoubleClick cookie) together to inform and optimize serve ads based

At the MRC he developed novel prostate cancer therapeutics based upon his research into GPCR pluridimensional Stuart’s current research, in the Receptor Biology Lab, focuses on the development of novel GPCR-based therapeutics that interdict diseases based on their gerontological underpinnings. This research stream is now forming the basis of a new technology-based start-up company, HeptOME , to

At the MRC he developed novel prostate cancer therapeutics based upon his research into GPCR pluridimensional Stuart’s current research, in the Receptor Biology Lab, focuses on the development of novel GPCR-based therapeutics that interdict diseases based on their gerontological underpinnings. This research stream is now forming the basis of a new technology-based start-up company, HeptOME , to

At the MRC he developed novel prostate cancer therapeutics based upon his research into GPCR pluridimensional Stuart’s current research, in the Receptor Biology Lab, focuses on the development of novel GPCR-based therapeutics that interdict diseases based on their gerontological underpinnings. This research stream is now forming the basis of a new technology-based start-up company, HeptOME , to

His main area of research focuses on the structural and pharmacological bases for hormone-mediated activation We continue to utilize these data to better understand the basis for receptor-G protein specificity and Our mission is to understand the mechanism and structural bases for ligand binding and efficacy to help One example of our recent work surrounds a structure-based effort to develop ligands that specifically The Sunahara lab has also been developing protein-based therapeutics using structure-guided design and

Delbrueck Center in Berlin, I consolidated my knowledge of GPCRs pharmacology while performing various cell-based In addition, I generated various optical biosensors based on fluorescence or bioluminescence resonance

investigated the pH-dependent migration of GPR4 wildtype/overexpressing SK-Mel-28 cells by using an impedance-based SK-Mel-28 cells was enhanced in a range of pH 6.5 - pH 7.5 as compared to controls in the impedance-based

Approach for Drug Discovery for Human Adhesion GPCRs Stephanie Häfner bioSens-All: A Multiparametric BRET-Based Laurent Sabbagh Characterizing hADGRE5/CD97 Activation and Signaling: A Mechanical Stimulation BRET-Based Stephanie Häfner on the web LinkedIn Scholz Lab Langenhan Lab bioSens-All: A Multiparametric BRET-Based Pharmacology-Enabling Drug Discovery Laurent Sabbagh Abstract "The 3rd generation bioSens-All platform combines BRET-based Domain Therapeutics Characterizing hADGRE5/CD97 Activation and Signaling: A Mechanical Stimulation BRET-Based

We sought to develop RGS2 inhibitors as potential chemotherapeutic agents utilizing structure-based drug This is the first group of RGS2 inhibitors identified by structure-based approaches and that show anticancer

evolutionary analysis of five fish-specific CCRs (CCR4La, CCR4Lc, CCR12a1, CCR12a2, and CCR12b) in largemouth bass fish-specific CCRs, namely CCR4La, CCR4Lc, CCR12a1, CCR12a2, and CCR12b, were identified in largemouth bass CCR4La/Lc, and CCL5, CCL8, CCL7, CCL13 and CCL26 might be that of largemouth bass CCR12a1/a2/b. Our results provided basis for elucidating the functions of chemokine-receptor complex in largemouth bass."

Much of his work is based on GPCR signaling in the context to cardiovascular diseases.

2024 From DNA day to GPCR genomics Read More May 14, 2024 Illuminating GPCR Research: FRET and BRET-Based October 1, 2022 GPCRs: Signal Transduction Read More GPCR Binders, Drugs, and More October 1, 2024 Target-based

Nanoengineering Materials Research Center and developing thermodynamic processing methods for Iron-based

Last summer, Julia worked at as the first-ever summer intern at Septerna, the GPCR-based biotechnology

his work is centered around dysregulated signaling in cancer and the development of novel mechanism-based

Ilana uses chemical biology-based methods to study the regulation and protein-protein interactions of

His current interests include the development of HTS fluorescence-based kinetic binding assays specifically

spending two years at the Cleveland Institute of Art, he earned degrees in Biochemistry and Chemistry from Case , systems and synthetic biologist, technologist, heavy CRISPR user, protein sequence- and structure-based

Research into their mechanism of action in purified systems formed the base of her thesis work.

Mokrosiński "Jacek is a Senior Scientist at Novo Nordisk specializing in molecular pharmacology and cell-based He works in a multidisciplinary Chemical Biology team based at the recently established US R&D hub in He is passionate about cell-based in vitro technologies to study mechanistic properties of GPCRs and He is an avid proponent of close collaboration between industry and academia." Dr.

Novoprotein developed a NovoiSMART technology, utilizing mRNA-based immunization, which can overcome Several case studies of GPCR and other multi-pass transmembrane targets are presented, including GPRC5D

2024 CINVESTAV, Mexico City, Mexico October 23-25 Register Rules for the logo contest Design must be based

My project involved the development of FRET/BRET -based GPCR conformational biosensors, which can be

understanding the interplay between GPCR signalling and trafficking in neurons using microscopy and proteomics based

Fiona and her team made considerable breakthroughs in the field of GPCR stabilization and structure-based

receptor) and ion channel (K, Ca, TRP channel) function; mostly electrophysiology and fluorescence-based

Richard Leduc, will carefully evaluate each submission based on originality, visual appeal, conceptual