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80 items found for "ascitic currents"
- Coincident Regulation of PLCβ Signaling by Gq-Coupled and μOpioid Receptors Opposes Opioid- Mediated
The current frontline approach for pain-management is the use of opioid analgesics.
- RAB-Symposium - Regulatory Autoantibodies Targeting GPCRs. September 15-16, 2022. Lübeck, Germany...
Therefore, the aim of this symposium is to bring together the current knowledge on the role of autoantibodies
- Targeting mGluR2/3 for treatment of neurodegenerative and neuropsychiatric diseases
In this review, we discuss what is currently known regarding the contribution of mGluR2 and mGluR3 to
- Deciphering the signaling mechanisms of β-arrestin1 and β-arrestin2 in regulation of cancer cell...
However, current investigations have now recognized that in addition to GPCR arresting (hence the name
- Professor Charlotte Deane Joins Exscientia as Chief Scientist of Biologics AI
She has held numerous senior roles at the University of Oxford, where she is currently Professor of Structural
- A NanoBRET-Based H 3 R Conformational Biosensor to Study Real-Time H 3 Receptor Pharmacology in...
In the current study, we have further characterized this H3R biosensor on intact cells by monitoring
- Accelerating GPCR Drug Discovery With Conformation-Stabilizing VHHs
to be regarded as one of the most tractable classes of drug targets and are targeted by 30%–40% of current
- Anosmin 1 N-terminal domains modulate prokineticin receptor 2 activation by prokineticin 2
In the current report we present evidence of the modulation of PK2/PKR2 activity by anosmin 1, since
- Lysophosphatidic Acid and Several Neurotransmitters Converge on Rho-Kinase 2 Signaling to Manage...
The aROCK2 inhibited pH-sensitive and TASK1-mediated currents in SMNs. both known to increase MN IME by TASK1 inhibition, stimulated ROCK2, and depressed background resting currents
- Pharmacological targeting of cGAS/STING-YAP axis suppresses pathological angiogenesis and...
Currently, a controversy exists as to whether cGAS/STING activation exacerbates inflammation and tissue
- Confo Therapeutics Doses First Subjects In Phase 1 Clinical Trial Of CFTX-1554 For The Treatment ...
debilitating condition caused by damage to the nerves outside of the brain and spinal cord, for which current
- Class B1 GPCR Dimerization: Unveiling Its Role in Receptor Function and Signaling
Current Opinion in Structural Biology, 2023. 80 : p. 102574. 2.
- Neurocrine Biosciences Presents Data on Treatment of Adolescent Patients with Classic Congenital ...
Crinecerfont Treatment in Adolescents with Classic CAH - Two Phase 3 Global Registrational Studies Currently
- Differences across sexes on head-twitch behavior and 5-HT2A receptor signaling in C57BL/6J mice
Current studies focused on the potentially clinical effects of psychedelics on human subjects tend to
- GPR3 expression in retinal ganglion cells contributes to neuron survival and accelerates axonal...
accelerates axonal regeneration after optic nerve crush in mice "Glaucoma is an optic neuropathy and is currently
- Biased GPCR signaling by the native parathyroid hormone-related protein 1 to 141 relative to its...
mature forms of PTHrP in the body consist of splice variants of 139, 141, and 173 amino acids, our current
- Functional molecular switches of mammalian G protein-coupled bitter-taste receptors
Using current knowledge on class A GPCRs and existing experimental data in the literature as constraints
- Harnessing Deep Mutational Scanning for Enhanced Drug Discovery
Finally, current sequencing technology restricts the mutagenizable region to about 300 amino acids, although
- Extracellular signal-regulated kinases – a potential pathway for GPCR-targeted drug discovery
Current Chemical Genomics and Translational Medicine, 7, 9. Kenakin, T. (2019).
- TLR4 biased small molecule modulators
Currently, attention was mainly paid to biased signaling modulators targeting G protein-coupled receptors
- Platelets in the NETworks interweaving inflammation and thrombosis
In light of the current COVID-19 pandemic, the topic of immunothrombosis has become more relevant than
- From DNA day to GPCR genomics
Current opinion in structural biology, 55, 161–177. https://doi.org/10.1016/j.sbi.2019.04.007 Papasergi-Scott
- The development of modulators for lysophosphatidic acid receptors: A comprehensive review
This article provides an extensive review on the current status of ligand development targeting LPA receptors
- 📰 GPCR Weekly News - January 2 to 8, 2023
Deadline February 12, 2023 Current Technologies To Understand G-Protein-Coupled Receptor Molecular Pharmacology
- 📰 GPCR Weekly News, November 6 to November 12, 2023
An image-based abplex method for high-throughput gpcrs antibody discovery Reviews, GPCRs, and more Current
- 📰 GPCR Weekly News
Deadline February 12, 2023 Current Technologies To Understand G-Protein-Coupled Receptor Molecular Pharmacology
- GPCRs Are Optimal Regulators of Complex Biological Systems and Orchestrate the Interface between ...
and Orchestrate the Interface between Health and Disease GPCRs arguably represent the most effective current
- 📰 GPCR Weekly News, September 25 to October 1, 2023
In addition, we are currently seeking a new logo for this renowned event.