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45 items found for "conformational dynamics"
- Ep 148 with Dr Arthur Christopoulos
hard work, failure, and differentiation in academic and personal lives, and the value of international conferences Postdoctoral Position, Scientific Dynamics, and New Drug Targets Arthur shared his decision to undertake He and Yamina discussed the importance of preserving original work, the value of international conferences , and the dynamics between junior and senior scientists in a research environment. this podcast episode This short survey will help us understand your needs to bring you exciting and informative
- Prediction of survival and immunotherapy response by the combined classifier of G protein-coupled receptors and tumor microenvironment in melanoma
Moreover, in silico analysis confirmed a potential binding site of miR-19a on the 3'UTR of GRK6 mRNA, and the subsequent luciferase assays confirmed the molecular binding between GRK6 and miR-19a.
- GPCR Retreat 2023 | Dr. GPCR Ecosystem
involved in deciphering how receptor activity-modifying proteins or RAMPs regulate GPCR function, is confirmed We have also confirmed Dr. Niznik keynote lecture , which will close the conference.
- Ep 150 with Dr GPCR Team
She subsequently joined Professor Mark Connor's laboratory at Macquarie University in Australia. Since beginning her undergraduate studies, she has used computational methods like molecular dynamics this podcast episode This short survey will help us understand your needs to bring you exciting and informative
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- Ep 151 with Dr GPCR Board
The precise control of PAR signaling is critical for proper temporal and spatial dynamics of signaling this podcast episode This short survey will help us understand your needs to bring you exciting and informative
- Ep 153 with Dr Jacek Mokrosiński
about cell-based in vitro technologies to study mechanistic properties of GPCRs and understanding the dynamics He also highlighted the benefits of attending conferences and engaging with colleagues, sharing examples this podcast episode This short survey will help us understand your needs to bring you exciting and informative
- AGPCR 24 Session III
Université de Montréal, Montreal, Quebec, Canada " About Ana Lilia Moreno Salinas "I am currently part of a dynamic
- Systems modeling of oncogenic G-protein and GPCR signaling reveals unexpected differences in downstream pathway activation
qualitative differences between seemingly interchangeable disease-promoting mutations, and our experiments confirmed power of mechanism-based computational systems biology as a discovery tool that can leverage available information
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- GPCR Courses
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- CircFKBP5 Suppresses Apoptosis and Inflammation and Promotes Osteogenic Differentiation
The dual-luciferase reporter, RNA immunoprecipitation (RIP), and pull-down assays were used to confirm
- RGS20 promotes non-small cell lung carcinoma proliferation via autophagy activation and inhibition of the PKA-Hippo signaling pathway
Lastly, in vivo experiments further confirmed role of RGS20 in aggravating tumorigenicity, as its overexpression
- AGPCR 24 Session VII
neurons expressing the DEG/ENaC channel pickpocket (PPK), which is involved in transduction of sensory information Knowledge of the structural dynamics of this complex is limited and pharmacological and in vivo systems
- Ep 154 with Dr Badr Sokrat
Yamina, who also attended the University of Montreal, confirmed her interest in science and mentioned He described a significant moment when he confirmed a previously uncertain interaction, underscoring She highlighted the importance of learning behind-the-scenes skills and staying informed through resources this podcast episode This short survey will help us understand your needs to bring you exciting and informative
- GPR68-ATF4 signaling is a novel prosurvival pathway in glioblastoma activated by acidic extracellular microenvironment
Low extracellular pH confers radioresistant tumors to glial cells. Our major indication, ferroptosis, was then confirmed by western blotting and qRT-PCR of reporter genes
- Ep 147 with Dr. Demet Araç
Next steps • Yamina will send an email to Demet, encouraging him to distribute information about the and will share the recording of the podcast with Demet for the same purpose. • Demet will distribute information Yamina shared her plans for an upcoming Doctor GPCR Symposium in June, for which Demet is the first confirmed this podcast episode This short survey will help us understand your needs to bring you exciting and informative