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113 items found for "cryo-EM structure"
- Ep 50 with Dr. Thomas P. Sakmar
Tom initially focused on structure-activity relationships underlying spectral tuning and identified a micro-domains” and the “helix movement model of receptor activation” were confirmed later when crystal structures
- Ep 79 with Dr. Graeme Milligan
His main research group centers on the function, structure, and regulation of G protein-coupled receptors
- Receptor autoantibodies: Associations with cardiac markers, histology, and function in human non-ischaemic heart failure
In patients, cardiac function, volumes, and myocardial structural properties were assessed by cardiac GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- The power of many: Multilevel targeting of representative chemokine and metabolite GPCRs in personalized cancer therapy
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- Ep 59 with Dr. Nicola J. Smith
Nicola J Smith is an expert in molecular pharmacology with a track record in exploring GPCR structure-function
- Ep 16 with Dr. Aaron Sato
He earned his Ph.D. at the Massachusetts Institute of Technology, where he studied MHC class II structure-function
- Ep 17 with Dr. Yamina Berchiche
During the past 2 decades, my research mainly focused on chemokine receptor structure/function relationships
- G protein-coupled receptor-mediated signaling of immunomodulation in tumor progression
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- Ep 15 with Dr. Arun Shukla
Arun first started working on GPCRs and their structural characterization at the Max Planck Institute
- Increased protease-activated receptor 1 autoantibodies are associated with severe COVID-19
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- Dopamine-Mediated Motor Recovery after Ischemic Stroke
The Tiberi Lab pursues the study of the molecular, structural, pharmacological and signaling features
- Ep 84 with Rosie Dawaliby
field of pharmacology and biochemistry of GPCR and the crucial role of the lipidic environment on their structure
- Chemokine Cxcl1-Cxcl2 heterodimer is a potent neutrophil chemoattractant
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- Chemokine N-terminal-derived peptides differentially regulate signaling by the receptors CCR1 and CCR5
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- Ep 114 with Dr. Robert F. Bruns
His doctoral dissertation was the first large-scale study of structure-activity relationships for adenosine
- Ep 140 with Dr Alix A J Rouault
that MRAP2 regulates the signaling of multiple G protein-coupled receptors (GPCRs) through different structural C-terminal tail is not a docking space for the arrestins, but rather a necessary modification leading to a structural
- CCR6 as a Potential Target for Therapeutic Antibodies for the Treatment of Inflammatory Diseases
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- Efferocytes release extracellular vesicles to resolve inflammation and tissue injury via prosaposin-GPR37 signaling
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- G Protein-coupled Receptor-mediated Membrane Targeting of PLCγ2 is Essential for Neutrophil Chemotaxis
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- Ep 65 with Dr. Sudarshan Rajagopal
Keith Moffat, he studied the structural mechanisms of bacterial photoreceptors using time-resolved Laue
- GprC of the nematode-trapping fungus Arthrobotrys flagrans activates mitochondria and reprograms fungal cells for nematode hunting
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- Ep 98 with Dr. GPCR Team
She developed expertise over the past two decades studying structure/function relationships of GPCRs
- GPR4 in the pH-dependent migration of melanoma cells in the tumor microenvironment
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- CB2 stimulation of adipose resident ILC2s orchestrates immune balance and ameliorates type 2 diabetes mellitus
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- CCR7 acts as both a sensor and a sink for CCL19 to coordinate collective leukocyte migration
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- Deciphering the genetic landscape of lumpy skin disease: Unraveling variable virulence through comprehensive genome sequence analysis in India
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- Orphan receptor GPR50 attenuates inflammation and insulin signaling in 3T3-L1 preadipocytes
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- Metallo-protease Peptidase M84 from Bacillusaltitudinis induces ROS-dependent apoptosis in ovarian cancer cells by targeting PAR-1
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
