FFAR4 improves the senescence of tubular epithelial cells by AMPK/SirT3 signaling in acute kidney injury

GPCR Activation and Signaling GPCR screening reveals that the metabolite receptor HCAR3 regulates epithelial Launches to Screen AI-Generated Virtual Libraries AbbVie to Acquire Cerevel Therapeutics in Transformative Transaction

Receptor, GPR3 After wounding, a G-protein coupled receptor promotes the restoration of tension in epithelial

Listen to her talk about her work and her transition to PI in Belfast.

phosphorylation After wounding, a G-protein coupled receptor promotes the restoration of tension in epithelial

OR51E2, initially assumed to be GPCRs only expressed in prostate tissue, play a role in prostate cancer epithelial

about State transitions of coupled Gi-protein: Insights into internal water channel dynamics within dopamine This transition will enable us to invest in higher-quality content and resources, ensuring our community Receptor determinants for ß-arrestin functional specificity at C-X-C chemokine receptor 5 (CXCR5) State transitions

We will first summarize their prominent roles in GPCR pharmacology before transitioning into less well-explored

dynamin-dependent endocytosis in HEK293 and Huh-7-Lunet cells after activation by glucagon within 5 min and transit

stem cell maintenance such as by employing hedgehog and WNT, which promote fibroblast-to-myofibroblast transition

Atomistic molecular dynamics simulations of opsin in a lipid membrane reveal conformational transitions

Gαs slow conformational transition upon GTP binding and a novel Gαs regulator.

GPCR Activation and Signaling New simulation insights on the structural transition mechanism of Bovine Molecular Pharmacology, Discovery Biology Staff Scientist/Senior Staff Scientist, Disease Biology and Translational

receptor Astrocytic GPCR signaling in the anterior cingulate cortex modulates decision making in rats Translation-independent transport of nascent G protein-coupled receptors Effects of an external static EF on the conformational transition

Methods & Updates in GPCR Research Activity Map and Transition Pathways of G Protein-Coupled Receptor

Let’s dive into the Classified GPCR News from January 8th to 14th, 2024 Adhesion GPCRs Conformational transitions

Group I Metabotropic Glutamate Receptors Dual regulation of IP3 receptors by IP3 and PIP2 controls the transition

., Structure of RGS4 bound to AlF4--activated G(i alpha1): stabilization of the transition state for

Transitioning to study Latrophilins, I decided to test the interaction of neurexins with Latrophilins

September 2022 "Sound is converted by hair cells in the cochlea into electrical signals, which are transmitted

G protein-coupled receptors (GPCRs) transmit extracellular signals to the inside by activation of intracellular

G protein-coupled receptors (GPCRs) are a vast family of membrane-bound proteins crucial for transmitting that non-cognate G protein interactions could modulate GPCR signalling pathways without initiating traditional It challenges the traditional view of strict cognate G protein coupling and suggests a more dynamic interaction

Developmental and homeostatic signaling transmitted by the G-protein coupled receptor FPR2.

These interactions induce local conformational changes which are amplified and transmitted to the intracellular in vivo efficacy in a highly stringent model of HIV transmission Steinbach, K. et al. (2019) Science Translational