Search Results
86 items found for "human"
- Ep 20 with Dr. Jennifer Pluznick
This work contributes to a better understanding of how the kidney helps maintain homeostasis in humans
- G Proteins and GPCRs in Cancer: Novel Precision Targeted and Immunotherapies
His research team has pioneered the study of G proteins and G protein coupled receptors (GPCRs) in human
- Ep 38 with Dr. Alexander S. Hauser
Department of Drug Design and Pharmacology in Copenhagen, he worked on novel analytical methods to identify human
- Ep 51 with Dr. Mark Connor
orthosteric and allosteric interactions, and still looking for some bias ... anywhere ... these days human
- GPCR Retreat Logo Contest | Dr. GPCR Ecosystem
many physiological processes, making them a focal point of scientific research with implications for human
- Ep 61 with About Dr. Marta Filizola
Professor in the Departments of Pharmacological Sciences, Neuroscience, and Artificial Intelligence and Human
- Ep 93 with Dr. Sri Kosuri
has worked on building large-scale ways of empirically exploring questions in protein biochemistry, human
- Ep 141 with Dr Tobi Langenhan
extends to the development of novel screening approaches to identify pharmacological modulators of human
- Ep 46 with Dr Gunnar Schulte
to find, create and optimize Frizzled-targeting small molecule drugs to improve future therapies of human
- Ep 33 with Dr. David E. Gloriam
. from Uppsala University in Sweden where he worked on the bioinformatic identification of 24 novel human
- Ep 18 with Dr. Yamina Berchiche
structural biology, and pharmacology can provide new opportunities to improve our understanding of human
- Ep 92 with Dr. Stephane Angers
families of growth factors and their signaling mechanisms in development, adult tissue homeostasis, and human
- Ep 109 with Dr. Katarina Nemec
Since my undergraduate studies, I have been engaged in researching molecular mechanisms that govern human
- GprC of the nematode-trapping fungus Arthrobotrys flagrans activates mitochondria and reprograms fungal cells for nematode hunting
dual localization of GprC in A. flagrans resembles the localization of the cannabinoid receptor CB1 in humans
- Autocrine proteinase-activated receptor signaling in PC3 prostate cancer cells
In this study, we examined the androgen-independent human prostatic cancer cell line PC3 and find the
- Ep 53 with Dr. Timo De Groof
platform to develop nanobodies targeting viral G protein-coupled receptors with a special focus on the human
- GPCRs and fibroblast heterogeneity in fibroblast-associated diseases
GPCRs regulate many functions in the human body and have earned the title of "most targeted receptors
- CB2 stimulation of adipose resident ILC2s orchestrates immune balance and ameliorates type 2 diabetes mellitus
of the endocannabinoid system, is expressed on both visceral adipose tissue (VAT)-derived murine and human
- Inhibition of Relaxin Autocrine Signaling Confers Therapeutic Vulnerability in Ovarian Cancer
A second area of interest has been the elucidation of the molecular basis for a rare autosomal human
- Pan-cancer functional analysis of somatic mutations in G protein-coupled receptors
mutations found in patient samples derived from the Genomic Data Commons and compared it to the natural human
- A virally encoded GPCR drives glioblastoma through feed-forward activation of the SK1-S1P1 signaling axis
Published date August 15, 2023 Abstract "The G protein-coupled receptor (GPCR) US28 encoded by the human
- In Silico Design of Novel RGS2-Galpha-q Interaction Inhibitors with Anticancer Activity
proteins are essential in regulating GPCR signaling, and most members are implicated as critical nodes in human
- Ep 43 with Dr. Stuart Maudsley
be the Principal Investigator of the Receptor Biology Section at the Medical Research Council (MRC) -Human
- GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis
GPR143 is elevated in multiple cancers, and quantitative proteomic and RNA profiling of exosomes in human
- Ep 54 with Dr. JoAnn Trejo
of GPCR biology, acquired critical expertise, and rigorous approaches to examine PAR1 function using human
- Gi/o GPCRs drive the formation of actin-rich tunneling nanotubes in cancer cells via a Gβγ/PKCα/FARP1/Cdc42 axis
Using a model of human adrenocortical cancer cells, here we established that activation of the GPCR OXER1
- Ep 71 with Dr. Jean Martin Beaulieu
genetic risk factors implicated in schizophrenia by large whole-genome association studies (GWAS) in humans
- Signaling by Neutrophil G Protein-Coupled Receptors that Regulate the Release of Superoxide Anions
Receptors that Regulate the Release of Superoxide Anions Published date July 26, 2024 Abstract "In human