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102 items found for "metabolism"
- Class B1 GPCR Dimerization: Unveiling Its Role in Receptor Function and Signaling
an important subclass of GPCRs that include 15 receptors involved in regulating body homeostasis and metabolism therapeutic agents that target specific receptor dimer states to modulate signaling in diseases related to metabolism
- 📰 GPCR Weekly News, January 8 to 14, 2024
April 22 - 23, 2024 | Endocrine Metabolic GPCRs Join us at the Endocrine Metabolic GPCRs event on April in Cardiology, Endocrinology, and Taste Propionate functions as a feeding-state-dependent regulatory metabolite
- Therapeutic validation of an orphan G protein-coupled receptor: The case of GPR84
emerging interest in defining if agonists of GPR84 might find utility in conditions in which regulation of metabolism
- 📰 GPCR Weekly News, March 4 to 10, 2024
GPCR Partnered Events April 22 - 23, 2024 | Endocrine Metabolic GPCRs Join the Endocrine Metabolic GPCRs
- Discovery and In Vivo Evaluation of ACT-660602: A Potent and Selective Antagonist of the Chemokine..
compound with high biological potency in inhibiting cell migration together with improvements of the metabolic
- Orion Announces The Rapid Lead Optimization Of Ob-004 - A Ccr2 Antagonist
The CCL2/CCR2 pathway plays an important role in oncology, inflammatory, metabolic, and neurological
- C3aR plays both sides in regulating resistance to bacterial infections
roles for C3aR in regulating innate immune cell inflammatory state, antimicrobial killing capacity, and metabolism
- GPCR News Flash! Top Updates You Can't-Miss! + University CheatSheet is finally available! ❄ Dec 2 - 8, 2024
Report SEP-786 Data In Mid-2025 How GPCR agonists, including antibodies, are shaping the future of metabolic different GPCR signaling pathways segregates the orexigenic activity from the control of whole-body glucose metabolism
- RAB-Symposium - Regulatory Autoantibodies Targeting GPCRs. September 15-16, 2022. Lübeck, Germany...
with a focus on small molecules and monoclonal antibodies for the treatment of cancer, infections, metabolic
- Biased Agonism at the GLP-1 Receptor: A Pathway to Improved Therapeutic Outcomes
The GLP-1R, a class B1 GPCR, is integral to metabolic regulation, particularly in glucose homeostasis biased agonism at the GLP-1R represents a promising strategy for optimizing therapeutic outcomes in metabolic Cell Metab, 2018. 27 (4): p. 740-756. 3.
- GPCR Signaling and mTORC1 Regulation
target of rapamycin (mTOR) senses upstream stimuli to regulate numerous cellular functions such as metabolism
- Functional modulation of PTH1R activation and signaling by RAMP2
hormone 1 receptor (PTH1R), a class B GPCR and an important modulator of mineral ion homeostasis and bone metabolism
- 📰 GPCR Weekly News, March 11 to 17, 2024
GPCR Partnered Events April 22 - 23, 2024 | Endocrine Metabolic GPCRs Join the Endocrine Metabolic GPCRs
- ADGRL3 genomic variation implicated in neurogenesis and ADHD links functional effects to the...
mutations in the ADGLR3 gene disrupt the standard and wild ADGRL3 structure, most likely affecting its metabolic
- 📰 GPCR Weekly News, February 19 to 25, 2024
April 22 - 23, 2024 | Endocrine Metabolic GPCRs Join Dr. GPCR Founder Dr. Yamina Berchiche at the Endocrine Metabolic GPCRs event in Birmingham, UK, on April 22-23, 2024. Reaction Orphan GPR52 as an emerging neurotherapeutic target Sustained antidepressant effects of ketamine metabolite
- 📰 Breaking Down the Latest GPCR Discoveries: a Weekly Update (Nov 27-Dec 3, 2023)
American Physiology Summit April 5 - 10, 2024 | AACR Annual Meeting April 22 - 23, 2024 | Endocrine Metabolic Scientific Assistant Scientist Lead Researcher Post-Doctoral Fellow Sr Scientist in Obesity, Muscle, and Metabolism
- 📰 GPCR Weekly News, November 13 to 19, 2023
American Physiology Summit April 5 - 10, 2024 | AACR Annual Meeting April 22 - 23, 2024 | Endocrine Metabolic Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Sr Scientist in Obesity, Muscle, and Metabolism
- Focusing on the role of secretin/adhesion (Class B) G protein-coupled receptors in placental...
Obesity, immunological diseases and endocrine metabolic diseases are high-risk factors for the development
- Obesity-induced changes in human islet G protein-coupled receptor expression: Implications for ...
Obesity-induced changes in human islet G protein-coupled receptor expression: Implications for metabolic
- 📰 GPCR Weekly News, January 22 to 28, 2024
Endocrine Metabolic GPCRs Join the Endocrine Metabolic GPCRs event in Birmingham, UK, on April 22-23
- Actions of Parathyroid Hormone Ligand Analogues in Humanized PTH1R Knockin Mice
pharmacologic activities and potential therapeutic utility toward diseases of bone and mineral ion metabolism
- Network pharmacological investigation into the mechanism of Kaixinsan powder for the treatment of...
in treating depression was involved in the biological process of GPCR signal transduction, hormone metabolism
- GRK2 in cardiovascular disease and its potential as a therapeutic target
critical myocardial signal transducers which regulate cardiac contractility, growth, adaptation and metabolism
- Microbial Metabolites Orchestrate a Distinct Multi-Tiered Regulatory Network in the Intestinal Epith
September 2022 Microbial Metabolites Orchestrate a Distinct Multi-Tiered Regulatory Network in the Intestinal These findings shed light on a sophisticated signaling network directed by intestinal microbial metabolites
- Induced Human Regulatory T Cells Express the Glucagon-like Peptide-1 Receptor
September 2022 "The glucagon-like peptide-1 receptor (GLP-1R) plays a key role in metabolism and is an
- 📰 GPCR Weekly News, April 8 to 14, 2024
GPCR Partnered Events April 22 - 23, 2024 | Endocrine Metabolic GPCRs Join the Endocrine Metabolic GPCRs
- HDX-MS-optimized approach to characterize nanobodies as tools for biochemical and structural ...
eukaryotes is the phosphoinositide 3-kinase (PI3K) pathway, which plays fundamental roles in growth, metabolism
- 📰 GPCR Weekly News, January 29 to February 4, 2024
April 22 - 23, 2024 | Endocrine Metabolic GPCRs Join the Endocrine Metabolic GPCRs event in Birmingham