Many G-protein-coupled receptors (GPCRs) including EP4 are localized in cilia for modulating cAMP signaling

residues spans from the extracellular surface to the transmembrane area, linking with canonical class A GPCR activation motifs to initiate proton-sensing GPCRs.

cryo-EM has enabled insights into important drug target families such as G protein-coupled receptors (GPCRs

Given that postsynaptic latrophilin adhesion-GPCRs drive synapse formation and produce cAMP, we suggest

Numerous physiological effects of melatonin are mediated via its specific G protein-coupled receptors (GPCRs human and guinea pig airway smooth muscle and cultured human airway smooth muscle (HASM) cells by RT-PCR

Further difficulties arise from the existence of cross-reactivity with other GPCRs and differences in of chemokine receptors which are regulated by globular protein ligands, unlike most of the class A GPCRs

G protein-coupled receptors (GPCRs) transmit extracellular signals to the inside by activation of intracellular

characterize ligand interactions with cell surface membrane proteins such as G-protein coupled receptors (GPCRs

"The effects of the neurohormone melatonin are mediated by the activation of the GPCRs MT1 and MT2 in

and review Odorant receptors (ORs) account for about 60% of all human G protein-coupled receptors (GPCRs

their functional activities are achieved by binding to the cell surface G protein-coupled receptors (GPCRs

is a key protein that mediates desensitization and internalization of G protein-coupled receptors (GPCRs

Colocalization of different actions of GPCRs provide synaptic integration within presynaptic terminals

dependent kinase inhibitor 1B; CQ: chloroquine; E2F1: E2F transcription factor 1; FBS: fetal bovine serum; GPCRs

Exendin-4, and possibly through G protein-coupled receptors (GPCRs), increases levels of cAMP and upregulates

Opioid receptors belong to class A of G protein-coupled receptors or GPCRs and signaled mainly through