Search Results
115 items found for "Bryan S Yung"
- Mutation Patterns Predict Drug Sensitivity in Acute Myeloid Leukemia
Aguilar, Lauren Hagen, Jeannine McCune, Richard Gelinas, Raymond J Monnat Jr, Ilya Shmulevich, Pamela S
- LP2, a cyclic angiotensin-(1-7) analog extended with an N-terminal D-lysine, impairs growth of patient-derived xenografts of colorectal carcinoma in mice
and, together with its excellent specificity, safety and stability, warrant further evaluation of LP2's
- Ep 69 with Dr. Stephen Ferguson
Brian Collier in the Department of Pharmacology and Therapeutics at McGill University (1994).
- CircFKBP5 Suppresses Apoptosis and Inflammation and Promotes Osteogenic Differentiation
differentiation of hDPSCs was investigated by performing alkaline phosphatase (ALP) staining and alizarin red S
- Single cell G-protein coupled receptor profiling of Transcription factor 21 expressing activated kidney fibroblasts
L Advani , Phelopater Sedrak , Laurette Geldenhuys , Karthik K Tennankore , Penelope Poyah , Ferhan S
- Opposite Effects of Src Family Kinases on YAP and ERK Activation in Pancreatic Cancer Cells: Implications for Targeted Therapy
The results provide rationale for considering a combination(s) of FDA-approved SFK (dasatinib) and MEK
- Regulator of G protein signaling protein 6 alleviates acute lung injury by inhibiting inflammation and promoting cell self-renewal in mice
News < GPCRs in Oncology and Immunology Regulator of G protein signaling protein 6 alleviates acute lung protein-coupled receptor (GPCR)-related genes and differentially expressed genes (DEGs) in an acute lung RGS6 plays a protective role in ALI not only in early inflammatory responses but also in endogenous lung Li , Cuicui Chen , Jian Zhou , Linlin Wang , Yu Yan , Jun She , Lin Tong , Yuanlin Song Tags Acute lung
- In Silico Design of Novel RGS2-Galpha-q Interaction Inhibitors with Anticancer Activity
Authors Adam Bair, Natalie Printy, So Hee Choi, Joshua Wilkinson, Joseph O'Brien, Brian Myers, David
- Ultrasensitive dose-response for asbestos cancer risk implied by new inflammation-mutation model
Mesothelioma and lung cancer induced by exposure to carcinogenic (e.g., certain asbestos) fibers in humans This theory is reviewed, implications of this theory are discussed in relation to mesothelioma and lung Author Kenneth T Bogen Tags Asbestos , Cytotoxicity , Inflammation , Lung cancer , Mesothelioma , Mutation
- Prediction of survival and immunotherapy response by the combined classifier of G protein-coupled receptors and tumor microenvironment in melanoma
Authors Kangjie Shen , Qiangcheng Wang , Lu Wang , Yang Yang , Min Ren , Yanlin Li , Zixu Gao , Shaoluan Zheng , Yiteng Ding , Jiani Ji , Chenlu Wei , Tianyi Zhang , Yu Zhu , Jia Feng , Feng Qin , Yanwen Yang
- Ep 66 with Dr. Antony A. Boucard Jr
Boucard´s lab focuses on molecular and cellular mechanisms underlying the function of adhesion GPCRs
- Stimulation of ectopically expressed muscarinic receptors induces IFN-γ but suppresses IL-2 production by inhibiting activation of pAKT pathways in primary T cells
Authors Trang T T Nguyen , Wen Lu , Wandi S Zhu , K Mark Ansel , Hong-Erh Liang , Arthur Weiss .
- Activation of PI3K/Akt pathway by G protein-coupled receptor 37 promotes resistance to cisplatin-induced apoptosis in non-small cell lung cancer
G protein-coupled receptor 37 promotes resistance to cisplatin-induced apoptosis in non-small cell lung cancer Published date September 21, 2023 Abstract "Objectives: Lung cancer is a major public health protein-coupled receptor 37 (GPR37) exhibits unknown functions in tumors, particularly in non-small-cell lung
- Ep 90 with Dr. Nariman Balenga
Druey at NIAID/NIH, where I characterized the role of RGS4 and RGS5 in airway hyperresponsiveness and lung fascinated by the multitude of processes that are regulated/dysregulated by GPCRs and RGS proteins in the lungs
- Ep 150 with Dr GPCR Team
As a young researcher fascinated by chemokine receptors, molecular pharmacology, drug discovery, and During that time, I investigated the effect of lung cancer-related mutations in the GAIN domain of the
- Session IV | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Assistant Professor in the Department of Neuroscience at Baylor College of Medicine, where he studies BAI1's
- Evolutionary diversity of CXCL16-CXCR6: Convergent substitutions and recurrent gene loss in sauropsids
CXCR6 deficiency lowers TRM cell numbers in the lungs and depletes ILC3s in the lamina propria, impairing Notably, single-cell RNA sequencing of the lung shows a drop in TRM cells in species with CXCR6 loss,
- Dr. GPCR Community Presentation | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Monserrat Avila Zozaya "My doctoral research was focused on investigating the cellular effects of missense lung
- Ep 97 with Robert Laprairie
He was the 2018 and 2021 recipient of the Young Investigator of the Year Awards from the British Pharmacological
- GPR68-ATF4 signaling is a novel prosurvival pathway in glioblastoma activated by acidic extracellular microenvironment
Authors Charles H Williams , Leif R Neitzel , Jessica Cornell , Samantha Rea , Ian Mills , Maya S Silver
- Complex Allosteric Cannabinoid Receptor Pharmacology
Devane Young Investigator Award from the International Cannabinoid Research Society (ICRS).
- Ep 134 with Dr. Neil Grimsey
p38 signaling responses we are studying how atypical p38 controls the onset and pathogenesis of acute lung
- Ep 63 with Dr. Khaled Abdelrahman
Canadian Society of Pharmacology and Therapeutics Postdoctoral and Publication awards along with many Young
- [Inhibitory effect of downregulating G protein-coupled receptor class C group 5 member A expression on lipopolysaccharide-induced inflammatory response in human gingival fibroblasts]
Authors Y H Hu , L L Shang , S H Ge Source Contribute to the GPCR News Coming soon Become a Contributor
- Noval insights and therapeutic strategies for tumor-induced kidney pathologies
Authors Meng Wang, Yong Han, Chao Zhang Source Contribute to the GPCR News Coming soon Become a Contributor
- A positive Allosteric Modulator of M1 Acetylcholine Receptors Improves Cognitive Deficits in Male and Female Alzheimer’s Mice
Canadian Society of Pharmacology and Therapeutics Postdoctoral and Publication awards along with many Young
- Illuminating Functional Selectivity and Allosterism at GPCRs.
received many awards, including a Canada Research Chair, FRSQ scholarships and the CDA/CSEM/Merck Frosst Young
- High Metabolite Concentrations in Portal Venous Blood as a Possible Mechanism for Microbiota Effects on the Immune System, and Western Diseases
Such pro-inflammatory immune cells may travel to tissues such as the brain, the lung, the kidney etc