We have gathered 24 new research papers on GPCRs and updates on industry news related to GPCRs.   Kawthar Belkacemi , Philippe Rondard , Jean-Philippe Pin , and Laurent Prézeau ,   for their research in Oncology and Immunology Metabolic crosstalk: Extracellular ATP and the tumor microenvironment in cancer progression and therapy Agonists of galanin subtype 2 receptor may prevent pancreatic cancer and agonists of angiotensin II type 2 receptor may prevent colorectal cancer Distinct Activation Mechanisms of CXCR4

to: Makaía M Papasergi-Scott, Peter Gmeiner, Brian K Kobilka, Georgios Skiniotis, et al. for their research Interested in showcasing your research? April 22 - 23, 2024 | Endocrine Metabolic GPCRs Join the Endocrine Metabolic GPCRs event in Birmingham, UK Therapeutics and Chime Biologics announce manufacturing agreement  to advance novel anti-CCR8 antibody  for cancer , optical imaging, substance use disorder, pharmacology Research Fellow Postdoctoral Fellow – Molecular

The researchers found that certain GPCRs, such as vasopressin receptors, were expressed in hematopoietic The researchers conducted a comparative analysis with previous studies, notably the work by Groot-Kormelink also opens doors for exploring the roles of these receptors in various pathological states, including cancer understanding of GPCR expression in human immune cells and platelets, providing a valuable resource for future research As the field continues to evolve, the insights gained from this research will be instrumental in shaping

Sandra Berndt, Ines Liebscher, and Susanne Horn et. al for their for their research on adhesion GPCR April 22 - 23, 2024 | Endocrine Metabolic GPCRs Join the Endocrine Metabolic GPCRs event in Birmingham, UK Cryo-electron microscopy for GPCR research and drug discovery in endocrinology and metabolism Reviews , GPCRs, and more Butyrate as a promising therapeutic target in cancer: From pathogenesis to clinic ( - Single-molecule Imaging Center Scientific Assistant Postdoctoral Fellowship- Mechanistic Biology Research

Gi/o GPCRs drive the formation of actin-rich tunneling nanotubes in cancer cells via a Gβγ/PKCα/FARP1 Autocrine proteinase-activated receptor signaling in PC3 prostate cancer cells. Methods & Updates in GPCR Research GPCRana: A web server for quantitative analysis of GPCR structures Drug Interactions of GPCRs, Ion Channels, and Transport Proteins (March 24 - 29, 2024) GPCR Jobs NEW Research Scientist II DOE (Native Mass Spectrometry) Senior Vice President of Global Medical Affairs Postdoctoral Research

Stay informed and up to date with the latest GPCR research and industry news. Chakit Arora, J Silvio Gutkind, and Francesco Raimondi for their work on The landscape of cancer-rewired protein-coupled receptor 141 expressed in myeloid cells functions as an inflammation suppressor The landscape of cancer-rewired neutrophil biology: inflammation, resolution and beyond Exploring GPCR signaling pathway networks as cancer Research Technologist I Join Dr.

The primary research question addressed in this study was: How do growth factors, specifically through The researchers focused on the phosphorylation of the G protein subunit Gαi at specific residues within phosphorylation events highlights a nuanced regulatory mechanism that could be crucial in contexts such as cancer GPCR-dependent pathways by growth factor signaling might contribute to altered cellular behaviors in cancer In conclusion, this research elucidates the molecular mechanisms by which growth factors influence G

January 2022 "G-protein-coupled receptors’ star has been on the rise in biotech in recent years as researchers discovered the vast potential for GPCR-targeting drugs in treating a range of health conditions, from cancer Among those hitching their wagons to that star are Verily and Sosei Heptares , which have struck a research

Caron and her team studied the GPER/GPR30 complex with β1-adrenergic receptor and AKAP5 in MCF7 breast cancer Metabolic GPCRs Join us at the Endocrine Metabolic GPCRs event on April 22-23, 2024 in Birmingham, UK guanylate kinase (MAGUK) scaffold protein, and protein kinase A anchoring protein (AKAP) 5 in MCF7 breast cancer July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Senior Researcher in Structural Biology NEW Post-Doctoral Fellow Postdoctoral Fellow Research Laboratory Specialist Associate

GPCRs in Oncology and Immunology Ovarian cancer G protein-coupled receptor 1 (OGR1) deficiency exacerbates Colorectal cancer incidence trends in Golestan, Iran: An age-period-cohort analysis 2004-2018. Methods & Updates in GPCR Research Evaluation of Drug Responses to Human β2AR Using Native Mass Spectrometry Interactions of GPCRs, Ion Channels, and Transport Proteins (March 24 - 29, 2024) GPCR Jobs NEW Senior Research Technologies NEW Computational Protein Design (GPCR) Postdoctoral Fellow, Caron Lab Clinical Trial Associate Research

Keep up-to-date with the latest research and advancements in the field with our convenient, weekly news An antibody-drug conjugate targeting GPR56 demonstrates efficacy in preclinical models of colorectal cancer Methods & Updates in GPCR Research Engineered Human Antibody with Improved Endothelin Receptor Type A Structure pulls off rare IPO, raising $161M 3-drug combo leads to 'unprecedented' response in pancreatic cancer Assistant Research Fellow - School of Physics and Astronomy Postdoctoral Research Associate (Fixed Term

Hello GPCR Community, Stay up-to-date with the latest GPCR research, including breakthrough studies, Nominated for Prestigious Prix Galien USA ‘Best Startup’ Award: Pioneering GPCR-Driven Immunotherapies in Cancer Russell to Board of Directors Adiso Announces Groundbreaking Research Highlighting ADS024 a Novel Oral position Senior or Lead Researcher   GPCR Activation and Signaling Profiling the proximal proteome of future directions Going rogue: mechanisms, regulation, and roles of mutationally activated Gα in human cancer

Antony Boucard's research on "Biased Signaling is Structurally Encoded As An Autoproteolysis Event in Methods & Updates in GPCR Research Fluorescent Ligands Enable Target Engagement Studies for the Intracellular Industry News Exscientia Initiates Prospective Observational Study in Ovarian Cancer. Undrugged GPCR Target in Four Months Cumulus Oncology and Leadxpro collaborate on small molecules targeting cancer-focused Robert Lefkowitz Lab Senior Research Specialist - Natural Sciences - Surgery Senior Scientist- Membrane

Recent research has unveiled the emergence of G-protein-independent pathways, particularly those involving In various pathological conditions, including cancer, aberrant ERK activity can lead to uncontrolled By understanding the intricacies of GPCR signaling and utilising advanced assay technologies, researchers ERK: a double-edged sword in cancer. ERK-dependent apoptosis as a potential therapeutic strategy for cancer. Cells, 10(10), 2509.

Yamina Berchiche at the Endocrine Metabolic GPCRs event in Birmingham, UK, on April 22-23, 2024. the G Protein-Coupled Receptor Rhodopsin Reviews, GPCRs, and more The dark sides of the GPCR tree - research News Exscientia Initiates Clinical Study to Further Evaluate Functional Precision Medicine Platform in Cancer Single-molecule Imaging Center NEW Scientific Assistant Postdoctoral Fellowship- Mechanistic Biology Research Scientist Post-Doc position Lead Researcher Join Dr.

Dysfunction of B2R is also closely related to cancers and hereditary angioedema (HAE). review, we summarize the structure and function of B2R in relation to drug discovery and discuss future research

The sheer complexity of the cell and the astonishing diversity of diseases are just two reasons why researchers For example, chemotherapy, a powerful standard approach to kill fast-growing cancer cells, has the drawback Nevertheless, researchers have a host of new technologies at their disposal to develop targeted therapies

Autocrine Proteinase-Activated Receptor (PAR) signaling in PC3 prostate cancer cells. Methods & Updates in GPCR Research A Peptidisc-based Survey of the Plasma Membrane Proteome of a Mammalian GPCRs in Immunology and Oncology The GPCR–Gαs–PKA signaling axis promotes T cell dysfunction and cancer Confo Therapeutics Enters Into Research Collaboration For GPCR-Targeting Antibody Discovery With AbCellera on Gliovascular Unit of Glioblastoma Associate Director / Director, Clinical Operations Postdoctoral Research

Endocrine Metabolic GPCRs  Join the Endocrine Metabolic GPCRs event in Birmingham, UK, on April 22-23 parahaemolyticus Involvement of Protease-Activated Receptor2 Pleckstrin Homology Binding Domain in Ovarian Cancer Hemicyanine as a "Turn-On" Fluorescence Probe Industry News Domain Therapeutics awarded Hospital-University Research 2026 | 20th World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs Post-Doc position Lead Researcher Senior Researcher in Structural Biology Post-Doctoral Fellow Postdoctoral Fellow Research Laboratory

and infectious diseases (Proudfoot 2002), and in recent years attention has increasingly focused on cancer The involvement of chemokines and their receptors in several aspects of cancer biology, represents a A lot of effort has been put forward to target CKRs especially in cancer, nevertheless, targeting this receptors redundancy and the fact that different chemokine receptors are overexpressed and promote cancer the notion that redundancy is not a feature of the chemokine system (Nedjai et al. 2012), but more research

simplify the intricacies of GPCR pharmacology for practical application in both academic and industrial research scientists uncover “plant-like” behavior in important human cell regulator, opening up a new drug target for cancer Europe July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology GPCR Jobs HIGHLIGHT Research Scientist, Computational Chemistry Postdoc in GPCR mechanosensing   Postdoctoral Position Postdoctoral research spinal cord injury GPCRs in Oncology and Immunology Biochemical pharmacology of adenylyl cyclases in cancer

the Order of British Empire from King Charles III in recognition of his contributions to Biochemical Research Minireview: functional roles of tissue kallikrein, kinins, and kallikrein-related peptidases in lung cancer Methods & Updates in GPCR Research Profiling of basal and ligand-dependent GPCR activities by means of Graeme Milligan was awarded the Order of British Empire by King Charles III for services to Biochemical Research Proteins (March 24 - 29, 2024) GPCR Jobs NEW Postdoctoral Fellow, Caron Lab NEW Clinical Trial Associate Research

April 22 - 23, 2024 | Endocrine Metabolic GPCRs Join the Endocrine Metabolic GPCRs event in Birmingham, UK immune responses and regulates GBP1 expression through GPCR receptor Mthl10 Methods & Updates in GPCR Research founded by Cumulus Oncology, to develop therapeutics targeting G protein-coupled receptors to treat cancer Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Postdoctoral Fellowship- Mechanistic Biology NEW Research Scientist Post-Doc position Lead Researcher Senior Researcher in Structural Biology Post-Doctoral Fellow

Yamina Berchiche at the Endocrine Metabolic GPCRs event in Birmingham, UK, on April 22-23, 2024. infection Industry News InterAx Biotech's AI platform unlocks new drug designs for diabetes, obesity, and cancer Heptares Operational Highlights and Consolidated Results for 12 Months ended 31 December 2023 Pioneering Research Workshop July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Research - Single-molecule Imaging Center Scientific Assistant Postdoctoral Fellowship- Mechanistic Biology Research

take a moment to explore our most recent coverage of GPCRs this week, which includes 15 insightful research Stay informed with the most recent developments in GPCR research and industry news. Join the global GPCR community to present your research—submit your abstract using this form. correlation study of adhesion G protein-coupled receptors as potential therapeutic targets for breast cancer function in autophagy control: a systematic approach of chemical intervention Methods & Updates in GPCR Research

and Immunology [1,2,4]Triazolo[1,5-c]pyrimidines as Tools to Investigate A3 Adenosine Receptors in Cancer to Discuss Game-Changing GPCR-Targeting Immunotherapies at Sachs Associates' Biotech Forum Celtarys Research Europe 2024 Conference and Exhibition June 2 - 4, 2024 | Chemotactic Cytokines GPCR Jobs NEW Senior Research / Senior Researcher in Structural Biology Research Specialist Science Research Writer Postdoctoral Fellow Research Laboratory Specialist Associate Explore Dr.

back again: the lysophosphatidic acid-CCN axis in signal transduction NPFF stimulates human ovarian cancer sensor and a sink for CCL19 to coordinate collective leukocyte migration Methods & Updates in GPCR Research 2024 | SLAS Europe 2024 Conference and Exhibition June 2 - 4, 2024 | Chemotactic Cytokines GPCR Jobs Researcher / Senior Researcher in Structural Biology Research Specialist Science Research Writer Postdoctoral Fellow Research Laboratory Specialist Associate Postdoc Research Associate Director, Regulatory Affairs Research

This week, we have a comprehensive coverage of 12 GPCR research papers. This week's highlight includes congrats to: Luca Franchini and Cesare Orlandi for their research on Deorphanization Submit a few slides for a poster presentation to showcase your research and network with our community Deciphering a GPCR-lncRNA-miRNA Nexus: Identification of an Aberrant Therapeutic Target in Ovarian Cancer Research Technologist I Senior Scientist- Internal Medicine Research Unit Postdoctoral Scholar – Synaptic