inflammation is characterized by overexpression and heightened activity of type 2 cytokines, mediators and cells FeNO , Fractional exhaled nitric oxide , G-protein-coupled receptor , GPCR , Group 2 innate lymphoid cell , IL-31RA , IL-33R , IL-4Rα , IL-5Rα , ILC , ILC2 , IRF1 , IgE , Immunoglobulin E , Innate lymphoid cell immunoglobulin-like lectin 8 , Signal transducer and activator of transcription , Substance P , T helper type 2 cell

the orphan atypical cannabinoid receptor, GPR55 and its crosstalk with CB1R and CB2R in endothelial cells which I characterized the impact of a fungal allergenic source on the function of airway smooth muscle cells

Eldridge Distinguished Professor and Chair of the Department of Cell Biology & Physiology at The University Kathleen Caron on the web UNC-Chapel Hill Department of Cell Biology and Physiology UNC Lineberger Comprehensive

These might serve as allosteric agonists of PAR1 on endothelial cells and platelets, and thus might contribute Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR

Our laboratory is interested in the role of NMDA receptors not only on neurons, but also on other cells of the brain such as astrocytes, oligodendrocytes, and endothelial cells.

emphasizing the structural and evolutionary significance of TACR3 and provided an in-depth analysis of cell Chao Zhang Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call

P2Y12R activation can promote platelet aggregation and adhesion to cancer cells, promote tumor angiogenesis microenvironment Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call

developed expertise over the past two decades studying structure/function relationships of GPCRs using live-cell Her work focused on chemokine receptors, members of the GPCR family that control cell movement in the After a well needed break from the grind, I am now a scientific/business consultant for clients both Trejo’s research program is to gain a thorough and mechanistic understanding of processes that control cell acquired critical expertise, and rigorous approaches to examine PAR1 function using human cultured cells

interactions are highly relevant for its different physiological effects, e. g. the migration of immune cells Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR

focuses on understanding the molecular mechanisms of adhesion GPCRs (aGPCRs) in lymphatic endothelial cells

developed expertise over the past two decades studying structure/function relationships of GPCRs using live-cell Her work focused on chemokine receptors, members of the GPCR family that control cell movement in the Monserrat Avila Zozaya I did a PhD in cell biology at CINVESTAV, Mexico.

Fan is currently an associate professor of Pharmacology and Pathology and Cell Biology at Columbia University

Group 2 innate lymphoid cells (ILC2s) play a critical role in maintaining adipose homeostasis via the resistance Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call

moved to Mexico City to establish himself as an independent investigator integrating the department of Cell as various alternatively spliced isoforms thus potentially resulting in differential modulation of cell

Investigation, Molecular Pharmacology, British Journal of Pharmacology, and American Journal of Physiology-Cell

transcriptomic, proteomic, and phosphoproteomic differential expression data of GPR56 knockdown U373-GBM cells Signaling , TG2 Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call

Among the five somatostatin receptors, SST2 and SST3 are associated with apoptosis and cell cycle arrest Michel Afargan Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call

We have developed an array of fluorescent biosensors to map kinase activity in living cells and are exploring

Mechanistically, RGS16 restrained JNK/P38-mediated apoptosis in CRC cells through disrupting the recruitment , Fuao Cao Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call

classical G-protein-coupled receptor (GPCR), whereas C5aR2 is a nonclassical GPCR that tailors immune cell Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR

human peripheral blood, the neutrophil granulocytes (neutrophils) are the most-abundant white blood cells protein-coupled receptors (GPCRs), are critical for the elimination of pathogens and inflammatory insults, as well transactivation Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call

a virally encoded G protein-coupled receptor (GPCR) that is essential for silent infections within cells Gary C Chan Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call

Sudha Shenoy is currently an Associate Professor in Medicine & Cell Biology in the Division of Cardiovascular

Adhesion GPCRs September 25, 2024 The G Protein-Coupled Receptor GPR56 Is an Inhibitory Checkpoint for NK Cell BRET-Based Sensors Shed Light on Cellular Signaling Read More Read more articles from our Contributors Call

tissue-damage-associated inflammation that epigenetically recruits, activates and orchestrates stem cells , Mutation Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call

Her research focuses on understanding the fundamental cell biological mechanisms regulating GPCR activity

Delbrueck Center in Berlin, I consolidated my knowledge of GPCRs pharmacology while performing various cell-based

management of R&D projects and teams in the field of pharmacology, in prestigious academic laboratories as well and membrane protein biochemistry by studying membrane fusion and autophagy in yeast and mammalian cells