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64 items found for "Genome sequence"
- Novel Driver Strength Index highlights important cancer genes in TCGA PanCanAtlas patients
September 2022 "Background Cancer driver genes are usually ranked by mutation frequency, which does not Index (DSI) and the Normalized Driver Strength Index (NDSI), the latter independent of gene mutation frequency
- Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1
By sequestering GATOR1, LYCHOS promotes cholesterol- and Rag-dependent recruitment of mTORC1 to lysosomes
- High hedgehog signaling is transduced by a multikinase-dependent switch controlling the...
This effect involves the sequential and additive action of protein kinase A, casein kinase I, and the
- Targeted Activation of G-Protein Coupled Receptor-Mediated Ca 2+ Signaling Drives Enhanced Cartilage
[Ca2+]i signaling, increased cell proliferation, and enhanced matrix production in a CNO dose- and frequency-dependent
- Synaptic integration of subquantal neurotransmission by co-localized G protein coupled receptors in
Train-dependent presynaptic Ca2+ accumulation forces frequency-dependent recovery of neurotransmission
- 📰 GPCR Weekly News, February 5 to 11, 2024
pharmacotherapeutic development updates Methods & Updates in GPCR Research GPCR-BERT: Interpreting Sequential
- Chemokine receptor-targeted drug discovery: progress and challenges
In fact, the requirements in terms of safety margin, oral bioavailability, and frequency of administration
- 📰 GPCR Weekly News, July 1 to 7, 2024
Conserved Receptor OR11A1 Tongue-on-a-Chip: Parallel Recording of Sweet and Bitter Receptor Responses to Sequential