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69 items found for "Jana Selent"
- Systems Pharmacodynamic Model of Combination Gemcitabine and Trabectedin in Pancreatic Cancer Cells. Part II: Cell Cycle, DNA Damage Response, and Apoptosis Pathways
chemotherapy, and could potentially serve as a tool to predict combinatorial efficacy and assist in target selection
- Vasoactive intestinal peptide receptor 2 signaling promotes breast cancer cell proliferation by enhancing the ERK pathway
Treatment with KS-133, a VIPR2-selective antagonist peptide, significantly inhibited VIP-induced cell
- Ep 66 with Dr. Antony A. Boucard Jr
biasing latrophilins’ regulation of cyclic AMP pathways and for determining the magnitude of ligand selectivity
- Involvement of Protease-Activated Receptor2 Pleckstrin Homology Binding Domain in Ovarian Cancer: Expression in Fallopian Tubes and Drug Design
Subsequently, we selected a compound from a library of backbone cyclic peptides generated toward the
- Stimulation of ectopically expressed muscarinic receptors induces IFN-γ but suppresses IL-2 production by inhibiting activation of pAKT pathways in primary T cells
costimulation of both muscarinic receptors plus the TCR even led to reduced IL-2 expression, suggesting a selective
- GPCR Retreat 2023 - Part II
He has been also studying what aspects of GPCR signaling are regulated in a sex-selective manner and
- Trainee Symposium II
GPCR Title: Balancing G Protein Selectivity and Efficacy in the Adenosine A2A Receptor About Louis-Philippe
- LPA1-mediated inhibition of CXCR4 attenuates CXCL12-induced signaling and cell migration
Conversely, CXCL12-induced calcium signaling and migration were increased in LPAR1 knockout cells, and LPA1-selective
- Functional Assessment of Cancer-Linked Mutations in Sensitive Regions of Regulators of G Protein Signaling Predicted by Three-Dimensional Missense Tolerance Ratio Analysis
residues that overlap with pathogenic cancer mutations reported in the COSMIC cancer database were selected
- Exploration of prognostic and treatment markers in hepatocellular carcinoma via GPCR-related genes analysis
Univariant and multivariant Cox regression analyses, as well as least absolute shrinkage and selection
- Ep 145 with Dr John Janetzko
He discovered the National Chemistry Olympiad and was selected to attend a provincial training camp at This led to his participation in the National Training Program in Quebec City and his selection to represent
- Ep 107 with Dr. Roger Sunahara
Our goal is to develop safer beta2AR-selective ligands for the treatment of asthma and acute rescue therapy
- Ep 152 with Dr Arthur Christopoulos
collaboration with Patrick Sexton and Jim Burch, and the discovery of hybrid molecules with functional selectivity
