of the rod phototransduction system highlights the potential roles of phosphodiesterase 6 (PDE6) and guanylate

selectivity and allosteric modulation in angiotensin receptors: IUPHAR Review 34 "Functional advances have guided

insights into the regulation of aGPCRs via post-translational modifications of the Go protein, and offers guidance

At high cholesterol concentrations, LYCHOS bound to the GATOR1 complex, a guanosine triphosphatase (GTPase

The cyclic guanosine monophosphate (GMP)-adenosine monophosphate (AMP) synthase (cGAS)-stimulator of

regulation of metabolic processes in adipose tissue, liver, pancreas, adrenal, skeletal muscle, and gut

LINKED ARTICLES: This article is part of a themed issue on Structure Guided Pharmacology of Membrane

The TM domain acts as a functional component of Cya, guiding the assembly of the catalytic domain and

Our findings fill a gap in the understanding of CB1 allosteric regulation and could guide the rational

orientational selection supporting complex formation of a GPCR and a middle sized flexible molecule "A GA-guided

identifies small changes to the ligands that invert their pharmacological activity and thus helps to guide

Our guest is the wonderful Dr. Rosie Dawaliby! Watch the full video with a Dr.

Her expertise guided numerous global negotiations, conclusions of partnership agreements, and fostered

of GPR84 may potentially prove effective also in diseases associated with inflammation of the lower gut

Experimental approach: We used a bio-guided screening assay to identify novel MQs and placed them phylogenetically

have explored hydrophobic groups of different sizes on both sides of the five-membered ring scaffold guided

candidates to enter clinical trials, the first AI-driven precision medicine platform clinically validated to guide

drug discovery programs in key therapeutic areas Kallyope, pioneers in drug discovery involving the gut-brain biopharmaceutical company, and New York City-based Kallyope, pioneers in drug discovery involving the gut-brain

Our guest is none other than Dr. Juan Jose Fung, Principal Scientist, at GPCR Therapeutics.

Our first guest speaker is none other than Dr. Ben Myers!

Our guest is Mark Schmeizl!

Please refer to our Safe Meeting guidelines for information about how you can participate in the event

detected the mRNA and protein expression of the melatonin MT2 but not the MT1 receptor in native human and guinea formation through the MT2 receptor in HASM cells, and attenuated the relaxant effect of isoproterenol in guinea

Our guest is Dr. Peter Banks, Scientific Director at BioTek Instruments!

Our guest is Dr. Adriano Marchese!

Our guest is Dr. JoAnn Trejo!

Our guest is Dr. Tim De Groof!

Our guest is Dr. Ben Myers!