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277 items found for "Ji Hee Ha"
- Ep 143 with Dr Davide Calebiro
Davide’s work has been published in prestigious scientific journals such as Nature, Cell, New England He has served on multiple panels and committees, including the ENDO Annual Meeting Steering Committee
- GPCR Retreat | Dr. GPCR Ecosystem
Over the years, the meeting has grown into one of the most recognized international events in the field That reputation has led to broad participation from the Great Lakes region and beyond. The past few GPCR retreats have been held in : Niagara-on-the-lake (2022) Bromont, Québec (2019) Detroit
- Ep 103 with Dr Kathleen Caron
coupled receptors and receptor activity modifying proteins in vascular biology, the Caron laboratory has Caron has received numerous awards including a Burroughs Wellcome Fund Career Award in the Biomedical
- Ep 148 with Dr Arthur Christopoulos
His work has been applied to studies encompassing neurological and psychiatric disorders, cardiovascular He has received substantial, long-term support from international and national competitive, charitable Professor Christopoulos has over 360 publications, including in leading international journals such as Nature,Science and Cell, and has delivered over 180 invited presentations. He has also been the recipient of multiple awards, including the John J.
- Ep 149 with Dr Arthur Christopoulos
His work has been applied to studies encompassing neurological and psychiatric disorders, cardiovascular He has received substantial, long-term support from international and national competitive, charitable Professor Christopoulos has over 360 publications, including in leading international journals such as Nature,Science and Cell, and has delivered over 180 invited presentations. He has also been the recipient of multiple awards, including the John J.
- Small-molecule targeting of GPCR-independent noncanonical G-protein signaling in cancer
However, it has become evident that heterotrimeric G-proteins can also be activated via GPCR-independent GIV/Girdin has emerged as a prototypical non-GPCR activator of G proteins that promotes cancer metastasis
- [1,2,4]Triazolo[1,5-c]pyrimidines as Tools to Investigate A3 Adenosine Receptors in Cancer Cell Lines
this work, a structural investigation on the two position of the [1,2,4]triazolo[1,5-c]pyrimidines has Compound 20 has been tested on both A3 adenosine receptor positive cancer cell lines (CHO-A3AR transfected
- Interaction with the cell adhesion molecule NEGR1 affects mGluR5 cell signalling
Ribeiro has supervised eleven M.Sc. and six Ph.D. students, as well as five post-doctorate fellows. Ribeiro has 86 per reviewed scientific papers published in highly respected scientific journals, including She was able to have several grants approved in Brazil and abroad, which have granted her research group
- Identification of Small-Molecule Antagonists Targeting the Growth Hormone Releasing Hormone Receptor (GHRHR)
Class B1 GPCR peptides such, as growth hormone-releasing hormone (GHRH), have been proposed to bind in The GHRHR has recently been highlighted as a promising drug target toward several types of cancer and has been shown to be overexpressed in prostate, breast, pancreatic, and ovarian cancer. Indeed, peptide GHRHR antagonists have displayed promising results in many cancer models. However, no nonpeptide GHRHR-targeting compounds have yet been identified.
- C5aR2 receptor: The genomic twin of the flamboyant C5aR1
The functional relevance of C5aR2 appears to be context-dependent compared to the C5aR1, which has received The current study has attempted to close the gap by generating highly refined model structures of C5aR2
- Ep 107 with Dr. Roger Sunahara
His training has provided a strong foundation and appreciation for the applications of pharmacology, The structural work on the GPCR-G protein complexes have also revealed some unprecedented conformational More recently we have have been heavily engaged in studies to address the functional role of these dramatic The Sunahara lab has also been developing protein-based therapeutics using structure-guided design and computational approaches the Sunahara lab and collaborators developed a thermostable form of the enzyme that has
- SSTR2 positively associates with EGFR and predicts poor prognosis in nasopharyngeal carcinoma
growth factor receptor (EGFR) belongs to the receptor tyrosine kinases family and overexpression of EGFR has However, no studies have examined the EGFR and SSTR2 in NPC. CR) with high expression of SSTR2, high expression of EGFR, and high coexpression of SSTR2 and EGFR had high expression of EGFR, high coexpression of EGFR and SSTR2, and EGFR/SSTR2 anyone high expression had Additionally, SSTR2 has potential as a new biomarker for poor prognosis in NPC patients."
- Ep 55 with Mark Schmeizl
He has successfully built numerous global life science, leadership teams, & works closely with both clients
- Ep 09 with Lauren Celano
Working in a lab allows scientists to gain amazing hard and soft skills, which opens the doors to several great careers that many have not even considered, yet. Lauren has a science background and is passionate about helping talented scientists find their dream
- Ep 05 with Dr. Terry Hébert
Terry Hebert to chat about how he and his team has been adapting to the new reality of working remotely
- Ep 83 with Dr. Jean-Philippe Pin
Since then, he has been studying the allosteric modulation and activation mechanism of this family of
- Terms and Conditions | Dr. GPCR Ecosystem
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- Ep 112 with Julia Gardner
Julia has been working as a researcher in Duke's Rajagopal Lab since her first year as an undergraduate
- Ep 04 with Dr. Graciela Pineyro
Graciela has done extensive work on the molecular pharmacology of opioid receptors, exploring their signaling
- Complex Allosteric Cannabinoid Receptor Pharmacology
Robert and his lab have been interested in the molecular pharmacology of cannabinoids for nearly 10 years and he has published more than 50 studies in the field."
- GPCR Retreat 2023 - Part I
coupled receptors and receptor activity modifying proteins in vascular biology, the Caron laboratory has Caron has received numerous awards including a Burroughs Wellcome Fund Career Award in the Biomedical Slosky’s work has been recognized through several travel and research awards, including the William James Psychology Award, the Hank Yamamura Endowed Fellowship in Pharmacology, an NIH F32 Postdoctoral Fellowship
- Molecular characterization of breast cancer cell pools with normal or reduced ability to respond to progesterone: a study based on RNA-seq
"Background: About one-third of patients with estrogen receptor alpha (ERα)-positive breast cancer have Patients with ERα-positive/PR-negative tumors have shorter disease-free and overall survival than patients New evidence has shown that progesterone (P4) has an anti-proliferative effect in ERα-positive breast biological processes affected by PR and associated with G protein-coupled receptor (GPCR) pathways which have
- GPCR Retreat 2023 | Dr. GPCR Ecosystem
For the 22nd edition, the Organizing Committee has again lived up to the expectations by putting together We have also confirmed Dr. Indeed, for the Montebello 2023 edition, we have organized two trainee symposiums to acknowledge formally Your participation has already made this unique event a success. If you have any suggestions or comments for either this Retreat or future meetings, we look forward to
- Ep 22 with Dr. Kari Johnson
All through her career, the recurring theme in Kari’s work has been GPCRs and more specifically Metabotropic
- Ep 12 with Dr. Antonella Di Pizio
Today, Antonella has expanded her research to olfactory GPCRs and trace amine receptors.
- Ep 25 with Dr. Annette Gilchrist
Annette Gilchrist About this episode Originally, Annette wanted to be a medical doctor but as luck has Instead, she discovered research and started her Ph.D. the day she should have started medical school
- Ep 11 with Genemode
Jacob Lee and Jin Choe met in ninth grade in English class and have been friends since. Today, Genemod has built a freezer management tool and a project management tool where scientists can
- Ep 49 with Dr. Sudha Shenoy
Her laboratory has continued to work on identifying the molecular mechanisms that ascribe ubiquitin code