Search Results
72 items found for "Jin-Wu Wang"
- G protein coupled receptor transcripts in human immune cells and platelets
On average, the white cells studied expressed 160 receptor mRNAs (range, 123-206).
- CCR6 as a Potential Target for Therapeutic Antibodies for the Treatment of Inflammatory Diseases
Abstract " The CC chemokine receptor 6 (CCR6) is a G protein-coupled receptor (GPCR) involved in a wide range
- Chemoattractant receptor signaling in humoral immunity
sites on the receptor C termini, which dictates functional outcomes of β-arrestin-mediated signaling, ranging
- CCR7 acts as both a sensor and a sink for CCL19 to coordinate collective leukocyte migration
We further show that these self-generated gradients can sustain the long-range guidance of DCs, adapt
- GPR4 in the pH-dependent migration of melanoma cells in the tumor microenvironment
Migration of GPR4 overexpressing SK-Mel-28 cells was enhanced in a range of pH 6.5 - pH 7.5 as compared
- Expression prevalence and dynamics of GPCR somatostatin receptors 2 and 3 as cancer biomarkers beyond NET: a paired immunohistochemistry approach
A 12-point immunoreactive scoring (IRS) range was used for interpretation of the staining results.
- GPR56 signaling pathway network and its dynamics in the mesenchymal transition of glioblastoma
receptor 56 (GPR56/ADGRG1) is a multifunctional adhesion GPCR involved in diverse biological processes ranging
- Ascitic Shear Stress Activates GPCRs and Downregulates Mucin 15 to Promote OvarianCancer Malignancy
we developed a patient-based, boundary-driven computational fluid dynamics model to predict an upper range
- Gallein, G protein βγ subunits inhibitor, suppresses the TGF-α-induced migration of hepatocellular carcinoma cells via inhibition of the c-Jun N-terminal kinase
Published date November 13, 2024 Abstract "G protein-coupled receptor (GPCR) signaling regulates a wide range
- G protein-coupled receptors: A target for microbial metabolites and a mechanistic link to microbiome-immune-brain interactions
gut microbiota act as ligands for specific human G protein-coupled receptors (GPCRs) and modulate a range
- Wnt pathway inhibition with the porcupine inhibitor LGK974 decreases trabecular bone but not fibrosis in a murine model with fibrotic bone
Authors Hsuan Lung, Kelly L Wentworth, Tania Moody, Ariane Zamarioli, Apsara Ram, Gauri Ganesh, Misun Kang
- Deciphering a GPCR-lncRNA-miRNA Nexus: Identification of an Aberrant Therapeutic Target in Ovarian Cancer
Kashyap , Kar-Ming Fung , Chao Xu , Resham Bhattacharya , Priyabrata Mukherjee , Ciro Isidoro , Yong Sang
- Combinatorial depletions of G-protein coupled receptor kinases in immune cells identify pleiotropic and cell type-specific functions
Neutrophils lacking all four GRK family members show increased chemotactic migration responses to a wide range
- Removing the GPCR-mediated brake on exocytosis enhances insulin action, promotes adipocyte browning, and protects against diet-induced obesity
Lange and Annie Mary Lyle Chair in Cardiovascular Research, and Professor of Pharmacology, Ophthalmology
- Ep 142 with Dr Claudia Stäubert
Quick recap Yamina and Claudia had a wide-ranging discussion about Claudia's work on metabolites and
- Session III | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
identify novel pharmacological targets and contribute to the development of innovative treatments for a range