Search Results
81 items found for "Kallikrein-related peptidases"
- Involvement of Protease-Activated Receptor2 Pleckstrin Homology Binding Domain in Ovarian Cancer: Expression in Fallopian Tubes and Drug Design
Subsequently, we selected a compound from a library of backbone cyclic peptides generated toward the
- DANGER Signals Activate G-Protein Receptor Kinases Suppressing Neutrophil Function and Predisposing to Infection After Tissue Trauma
Mitochondrial (mt) formyl peptides (FP) activate G-protein coupled receptors (GPCR) like FPR1. mtDNA
- Esophageal and gastric cancer incidence trends in Golestan, Iran: An age-period-cohort analysis 2004 to 2018
The marked declines in EC incidence rates in Golestan relate to generational changes in its underlying
- Exploiting frequent and specific expression of PRL3 in pediatric solid tumors for first-in-child use of PRL3-zumab humanized antibody
We sought to profile the expression of PRL3 in pediatric tumors in relation to survival outcomes, expression
- Transcriptomic analysis of human cytomegalovirus to survey the indirect effects on renal transplant recipients
Result: The analysis of RNA-Seq data related to RT patients with HCMV active viremia led to the identification
- Systems Pharmacodynamic Model of Combination Gemcitabine and Trabectedin in Pancreatic Cancer Cells. Part II: Cell Cycle, DNA Damage Response, and Apoptosis Pathways
Part I described the proteomic workflow and drug effects on the upstream portion of the SPD model related
- Lactate receptor GPR81 drives breast cancer growth and invasiveness through regulation of ECM properties and Notch ligand DLL4
increased spheroid necrosis, reduced invasion and in vivo tumor growth, and altered expression of genes related
- Molecular docking and dynamics simulation studies uncover the host-pathogen protein-protein interactions in Penaeus vannamei and Vibrio parahaemolyticus
this study was conducted to identify the interaction sites and binding affinity between several immune-related
- Activation of PI3K/Akt pathway by G protein-coupled receptor 37 promotes resistance to cisplatin-induced apoptosis in non-small cell lung cancer
Objectives: Lung cancer is a major public health concern and represents the most common cause of cancer-related
- Expression pattern and clinical significance of beta 2-adrenergic receptor in oral squamous cell carcinoma: an emerging prognostic indicator and future therapeutic target
The present study aimed at investigating the β2-AR gene expression and its significance in relation with
- Ep 152 with Dr Arthur Christopoulos
discussed Arthur's career journey in pharmacology, including his mentors and significant discoveries related They reviewed significant early papers related to the topic, including work by Brian Roth, Terry Kenakin
- Interplay between G protein-coupled receptors and nanotechnology
naturally nanosized, and spontaneously formed nanoaggregates of GPCRs (natural nano-GPCRs) may enhance GPCR-related
- Investigating isoform switching in RHBDF2 and its role in neoplastic growth in breast cancer
Published date November 1, 2022 Abstract Background: Breast cancer is the second leading cause of cancer-related
- Ep 150 with Dr GPCR Team
During that time, I investigated the effect of lung cancer-related mutations in the GAIN domain of the
- Unbiased multitissue transcriptomic analysis reveals complex neuroendocrine regulatory networks mediated by spinal cord injury-induced immunodeficiency
genes (hub genes: Grm4, Nmu, P2ry12, rt1-bb1, Oprm1, Zfhx2, Gpr83, and Chrm2) were enriched in pathways related
- Ep 142 with Dr Claudia Stäubert
Claudia and Yamina discussed the challenges of studying metabolites and their receptors, particularly in relation
- Session VIII * | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Cupidon mutants, similar to starved wild-type cells, upregulate various extracellular matrix-related
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Publishers may not sell or transmit to others any data about a user related to the user's use of any GPCR Button, the button action must be related to the Publisher or the Publisher's content.
- Session III | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
BRET-based biosensors that are highly adaptable to the needs of discovery projects for small molecules, peptides
- Ep 145 with Dr John Janetzko
Yamina emphasized that the content should be kept in a PG-13 context and be scientifically related to
- Ep 144 with Dr Aurélien Rizk
emphasizing the fascination of understanding how cells respond to gradients and signals, particularly in relation
- Ep 146 with Dr Michael Feigin
genes are dysregulated in cancer, which led him to explore different aspects of gene regulation and its relation
- Content and Conduct Policy | Dr. GPCR Ecosystem
Please note that Ecosystem.DrGPCR.com is specialized in GPCR and related subjects.
- Posters | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
This study aimed to understand the effects of GPR110 on mouse behaviors in relation to neurodevelopmental
- Ep 154 with Dr Badr Sokrat
benefits of maintaining a supportive network and engaging in non-lab activities for mental processing and relaxation