Small molecules targeting the subunits of Gα and Gβγ have been developed as cancer therapeutics.

demonstrate that BLT2 mediates macrophage migration during inflammation, which implicates it as a potential therapeutic

Furthermore, their modulation could be considered as a promising approach in lung cancer therapeutics

receptors would be a significant breakthrough in cardiovascular biology as they could be targeted for therapeutic

Developing a GPR176 inverse agonist or allosteric modulator is a promising therapeutic approach for fibrosis

Yamina will schedule a future talk with Jacek about GPCRs as therapeutic modalities. The discussion revealed their interest in GPCRs as therapeutic modalities and possible future collaborations

Michael Feigin is an Associate Professor in the Department of Pharmacology and Therapeutics, and Director of Graduate Studies of Experimental Therapeutics at Roswell Park Comprehensive Cancer Center in Buffalo disrupting histone processing on rapidly proliferating cells, such as cancer cells, and suggested a therapeutic

drug action and is known for applying binding and signaling kinetics to the development of effective therapeutics

Our results suggest that GPR15/GPR15L have a pathogenic role in RA and their antagonizing could be a therapeutic

better understanding of metabolite-sensing GPCRs, such as GPR109A, could establish their potential as therapeutic

targeting the Gs-GPCR or components of the downstream signaling pathway could serve as a promising therapeutic

controlling the functions of monocytes and dendritic cells and that targeting GPR141 may be a possible therapeutic

understanding of the designated value of GPCRs for molecular engineering of biomaterials with GPCRs in therapeutical

In the past, studies predicting therapeutic drug targets for cancer therapy focused on the assumption

understanding the molecular basis for human tumor development and how to use this knowledge to devise new therapeutics Van Meir has developed novel therapeutic approaches for cancer using oncolytic adenoviruses and anti-angiogenic

Moreover, our findings propose a therapeutic potential in combined CXCR4 and LPA1 inhibitors for cancer

Award and the Goodman and Gilman Award from the American Society for Pharmacology and Experimental Therapeutics Institute, highlighting its translational approach to research and its capacity to translate research into therapeutic

These findings provide a promising therapeutic approach to selectively induce ferroptosis in glioblastoma

San Diego Read More Friday, November 3rd / 3:55 PM Inhibition of Relaxin Autocrine Signaling Confers Therapeutic

University of Copenhagen, Copenhagen, Denmark. (2) Department of Psychiatry and Molecular Pharmacology and Therapeutics Columbia University Vagelos College of Physicians and Surgeons, New York, USA; Division of Molecular Therapeutics