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216 items found for "Lauren T May"

  • 📰 GPCR Weekly News, April 17 to 23, 2023

    GPCR Symposium on GPCR Activation and Signaling, May 19th, 2023. Meetings, and Webinars ASPET 2023 - American Society for Pharmacology and Experimental Therapeutics (May (May 22 - 26, 2023) 2nd LEAPS Meets Life Sciences Conference. (May 14 - 19, 2023) 8th and final ERNEST Meeting in Crete. (May 3 - 7, 2023).

  • 📰 GPCR Weekly News, April 24 to 30, 2023

    GPCR Symposium on GPCR Activation and Signaling on May 19th, 2023. Meetings, and Webinars ASPET 2023 - American Society for Pharmacology and Experimental Therapeutics (May (May 22 - 26, 2023) 2nd LEAPS Meets Life Sciences Conference. (May 14 - 19, 2023) NEW PEGS Boston (May 15 - 19, 2023) 8th and final ERNEST Meeting in Crete. (May 3 - 7, 2023). The Illuminating the Understudied Druggable Proteome Conference.

  • 📰 GPCR Weekly News, March 11 to 17, 2024

    GPCR University Save the date for our upcoming workshop, starting May 9th, 2024, featuring Dr.  3D Protein Structure Prediction of Large, Complex Protein Structures Newly discovered adhesion GPCR mayo Discovery Chemistry April 4 - 7, 2024 | American Physiology Summit April 5 - 10, 2024 | AACR Annual Meeting May 13 - 17, 2024 | 20th Annual PEGS Boston Summit May 16 - 19, 2024 | ASPET 2024 May 27 - 29, 2024 | SLAS

  • 📰 GPCR Weekly News, March 25 to March 31, 2024

    Samuel Hoare on Advanced data analysis for GPCR pharmacology, which will be held on Thursdays between May 9th and May 30th, 2024, from 10 am to 12 pm EDT. Discovery Chemistry April 4 - 7, 2024 | American Physiology Summit April 5 - 10, 2024 | AACR Annual Meeting May 13 - 17, 2024 | 20th Annual PEGS Boston Summit May 16 - 19, 2024 | ASPET 2024 May 27 - 29, 2024 | SLAS

  • 📰 GPCR Weekly News, February 26 to March 3, 2024

    Mark your calendar; we’re planning a workshop for May 2024 with Dr. Sam Hoare as our instructor. Discovery Chemistry April 4 - 7, 2024 | American Physiology Summit April 5 - 10, 2024 | AACR Annual Meeting May 13 - 17, 2024 | 20th Annual PEGS Boston Summit May 16 - 19, 2024 | ASPET 2024 May 27 - 29, 2024 | SLAS

  • Class B1 GPCR Dimerization: Unveiling Its Role in Receptor Function and Signaling

    Recent studies suggest that class B1 GPCRs can form both homodimers and heterodimers, which may play These dimeric interactions may contribute to the phenomenon of biased agonism, where ligands produce dimerization is critical for regulating GPCR function, particularly with respect to biased agonism, which may receptor's extracellular domain (ECD), facilitating the partial disengagement of the peptide while maintaining

  • 📰 GPCR Weekly News, April 3 to 9, 2023

    GPCR Symposium on GPCR Activation and Signaling held on May 19th, 2023. April 24 - 25, 2023) NEW ASPET 2023 - American Society for Pharmacology and Experimental Therapeutics (May (May 22 - 26, 2023) 2nd LEAPS Meets Life Sciences Conference. (May 14 - 19, 2023) 8th and final ERNEST Meeting in Crete. (May 3 - 7, 2023).

  • 📰 GPCR Weekly News, April 10 to 16, 2023

    GPCR Symposium on GPCR Activation and Signaling on May 19th, 2023. (April 24 - 25, 2023) ASPET 2023 - American Society for Pharmacology and Experimental Therapeutics (May (May 22 - 26, 2023) 2nd LEAPS Meets Life Sciences Conference. (May 14 - 19, 2023) 8th and final ERNEST Meeting in Crete. (May 3 - 7, 2023).

  • 📰 GPCR Weekly News, October 2 to 8, 2023

    2024 | Ligand Recognition and Molecular Gating Conference April 5 - 10, 2024 | AACR Annual Meeting May 13 - 17, 2024 | 20th Annual PEGS Boston Summit May 16 - 19, 2024 | ASPET 2024 May 27 - 29, 2024 | SLAS

  • Gαs and Gαq/11 protein coupling bias of two AVPR2 mutants (R68W and V162A) that cause nephrogenic di

    AVPR2 is a kind of G protein coupled receptor (GPCR) and mainly couples with Gαs protein leading to cAMP Investigation into the characterization of biased receptors may give insights into the relationship between Studies about the Gα protein coupling bias of mutant AVPR2s may broaden our understanding of the relationship between the changed conformation of the receptor and consequently activated signaling pathways, and also may

  • 📰 GPCR Weekly News, October 9 to 15, 2023

    2024 | Ligand Recognition and Molecular Gating Conference April 5 - 10, 2024 | AACR Annual Meeting May 13 - 17, 2024 | 20th Annual PEGS Boston Summit May 16 - 19, 2024 | ASPET 2024 May 27 - 29, 2024 | SLAS

  • 📰 GPCR Weekly News, October 23 to 29, 2023

    2024 | Ligand Recognition and Molecular Gating Conference April 5 - 10, 2024 | AACR Annual Meeting May 13 - 17, 2024 | 20th Annual PEGS Boston Summit May 16 - 19, 2024 | ASPET 2024 May 27 - 29, 2024 | SLAS

  • 📰 GPCR Weekly News, February 13 to 19, 2023

    GPCRs, and more Single nucleotide variations encoding missense mutations in G protein-coupled receptors may (May 22 - 26, 2023) 2nd LEAPS Meets Life Sciences Conference. (May 14 - 19, 2023) 8th and final ERNEST Meeting in Crete. (May 3 - 7, 2023).

  • 📰 GPCR Weekly News, December 4 to 10, 2023

    Physiology Summit April 5 - 10, 2024 | AACR Annual Meeting April 22 - 23, 2024 | Endocrine Metabolic GPCRs May 13 - 17, 2024 | 20th Annual PEGS Boston Summit May 16 - 19, 2024 | ASPET 2024 May 27 - 29, 2024 | SLAS

  • Primary cilia and SHH signaling impairments in human and mouse models of Parkinson’s disease

    Thus, increased SHH activity due to ciliary dysfunction may be required for the development of pathoetiological Inhibiting overactive SHH signaling may be a potential neuroprotective therapy for sPD."

  • 📰 GPCR Weekly News, October 16 to 22, 2023

    2024 | Ligand Recognition and Molecular Gating Conference April 5 - 10, 2024 | AACR Annual Meeting May 13 - 17, 2024 | 20th Annual PEGS Boston Summit May 16 - 19, 2024 | ASPET 2024 May 27 - 29, 2024 | SLAS

  • Domain Therapeutics Raises $42m Series A Financing

    May 2022 "Published: May 10, 2022 To accelerate clinical development of its best-in-class and first-in-class

  • 📰 GPCR Weekly News, February 5 to 11, 2024

    Discovery Chemistry April 4 - 7, 2024 | American Physiology Summit April 5 - 10, 2024 | AACR Annual Meeting May 13 - 17, 2024 | 20th Annual PEGS Boston Summit May 16 - 19, 2024 | ASPET 2024 May 27 - 29, 2024 | SLAS

  • Platelets in the NETworks interweaving inflammation and thrombosis

    Platelet α-granules contain microbicidal proteins, chemokines and growth factors, which upon release may negatively charged DNA within NETs provides a procoagulant surface, and in particular NET-derived proteins may Here, virus infiltration may lead to a cytokine storm that potently activates neutrophils and leads to

  • Functional modulation of PTH1R activation and signaling by RAMP2

    However, it is unknown whether and how RAMP proteins may affect PTH1R function. These data uncover a critical role of RAMPs in the activation and signaling of a GPCR that may provide

  • 📰 GPCR Weekly News, January 8 to 14, 2024

    Discovery Chemistry April 4 - 7, 2024 | American Physiology Summit April 5 - 10, 2024 | AACR Annual Meeting May 13 - 17, 2024 | 20th Annual PEGS Boston Summit May 16 - 19, 2024 | ASPET 2024 May 27 - 29, 2024 | SLAS

  • 📰 GPCR Weekly News, January 1 to 7, 2024

    Adhesion GPCRs The adhesion G-protein-coupled receptor mayo/CG11318 controls midgut development in Drosophila Physiology Summit April 5 - 10, 2024 | AACR Annual Meeting April 22 - 23, 2024 | Endocrine Metabolic GPCRs May 13 - 17, 2024 | 20th Annual PEGS Boston Summit May 16 - 19, 2024 | ASPET 2024 May 27 - 29, 2024 | SLAS

  • 📰 GPCR Weekly News, February 20 to 26, 2023

    Sometimes we may miss publications. (May 22 - 26, 2023) 2nd LEAPS Meets Life Sciences Conference. (May 14 - 19, 2023) 8th and final ERNEST Meeting in Crete. (May 3 - 7, 2023).

  • 📰 GPCR Weekly News, August 21 to 27, 2023

    Ligand Recognition and Molecular Gating Conference NEW April 5 - 10, 2024 | AACR Annual Meeting NEW May 13 - 17, 2024 | 20th Annual PEGS Boston Summit NEW May 16 - 19, 2024 | ASPET 2024 NEW May 27 - 29, 2024

  • Orion Shares New Data on its Latest Best-in-Class Drug Candidate

    June 2022 "Ottawa, Canada, May 10, 2022 — Orion Biotechnology Canada Ltd, a drug discovery and development important new data at both LSX World Congress and TIDES USA 2022 conference, taking place this week – May

  • 📰 GPCR Weekly News, September 18 to 24, 2023

    2024 | Ligand Recognition and Molecular Gating Conference April 5 - 10, 2024 | AACR Annual Meeting May 13 - 17, 2024 | 20th Annual PEGS Boston Summit May 16 - 19, 2024 | ASPET 2024 May 27 - 29, 2024 | SLAS

  • GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation

    increased under acute inflammatory stimuli such as lipopolysaccharide (LPS) and TNFα suggests that it may define a unique role of GPR84 in innate immune cells and intestinal inflammation, and suggest that GPR84 may

  • 📰 GPCR Weekly News, September 4 to 10, 2023

    2024 | Ligand Recognition and Molecular Gating Conference April 5 - 10, 2024 | AACR Annual Meeting May 13 - 17, 2024 | 20th Annual PEGS Boston Summit May 16 - 19, 2024 | ASPET 2024 May 27 - 29, 2024 | SLAS

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