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126 items found for "Libin Ye"
- 📰 GPCR Weekly News, September 11 to 17, 2023
Robert Lefkowitz on his 50 years at Duke. Congratulations. Dr. coupled receptors Industry News Duke University Celebrates Nobel Prize Winner Robert Lefkowitz’s 50 Years
- Decoding β-Arrestins: from Structure to function
Recent years have seen cryo-EM dominate new GPCR structure determinations, offering insight into GPCR-effector Future perspectives In recent years, remarkable strides have been taken in unraveling the intricacies
- 📰 GPCR Weekly News, August 7 to 13, 2023
disease therapy Primary cilia in skeletal development and disease Industry News Addex Reports 2023 Half Year
- 📰 GPCR Weekly News, July 31 to August 6, 2023
Indivior In Extended Substance Use Disorder Research Collaboration Addex Therapeutics To Release Half-Year
- 📰 GPCR Weekly News, July 10 to 16, 2023
GPCR-targeted Medicines OMass Therapeutics was shortlisted for ‘Life Sciences and Health Tech Company of the Year
- 📰 GPCR Weekly News, July 3 to 9, 2023
This year's symposium will feature a trainee day with a career panel.
- Structural landscape of the Chemokine Receptor system
In ACKR3, the presence of a tyrosine at position 6.40 plays a role in its constitutive activity (Yen, Schafer et al. 2022) which is also supported by mutagenesis studies (Han, Tachado et al. 2012, Yen,
- Artificial intelligence – faster, smarter, cheaper GPCR drug discovery
collaboration of data across academia, industry, and regulatory bodies will likely increase in the coming years
- 📰 GPCR Weekly News, April 24 to 30, 2023
Orion Biotechnology will be participating in a panel discussion at the LSX World Congress Novel living yeast-based
- Feeder or trigger – CCR2 as a scavenger and regulator of cell migration
likely to be mediated by changes in the cell motility machinery with receptor-specific switches not yet
- 📰 GPCR Weekly News, March 27 to April 4, 2023
Collaboration Agreement with Daiichi Sankyo to Discover Novel Medicines for CNS Diseases Addex Reports Full Year Corporate Update Sosei Heptares Announces the Publication of its Inaugural ESG Report, for the Financial Year with curriculum and deep reinforcement learning Structure Therapeutics Reports Fourth Quarter and Full Year
- 📰 GPCR Weekly News, March 20 to 26, 2023
Exscientia Business and Financial Update for the Full Year 2022.
- 📰 GPCR Weekly News, February 27 to March 5, 2023
Heptares and Neurocrine Biosciences won Top Out-Licensing Deal on the 8th annual Japan Deal of the Year
- 📰 GPCR Weekly News, February 20 to 26, 2023
GPCR Therapeutics on Beyond Biotech Podcast Crinetics Pharmaceuticals Reports Fourth Quarter And Full Year
- Unlocking the Therapeutic Potential of Previously Undruggable GPCRs
funding into small biotech companies developing novel technology platforms to target GPCRs in recent years Within the last two years, three investments stand out: · Tectonic Therapeutics: received $80 There is a great deal of scientific and business interest in solving this problem, and the last two years
- 📰 GPCR Weekly News
Hello Readers👋, Happy New Year! We're excited to be back and share our weekly newsletter! Industry News Sosei Heptares and Neurocrine Biosciences won Out-Licensing Deal of the Year from Locust
- Overview of adhesion GPCRs self-activation
However, at that time the structural conformation of the transmembrane (TM) region was not yet known. Fortunately, the scientific community has become increasingly interested in studying these proteins and this year
- Case Report of a Juvenile Patient with Autism Spectrum Disorder with a Novel Combination of Copy...
ADGRL3 (LPHN3) and Two Pseudogenes "We report the finding of two copy number variants (CNVs) in a 12-year-old
- Comparative studies of AlphaFold, RoseTTAFold and Modeller: a case study involving the use of...
receptors "Neural network (NN)-based protein modeling methods have improved significantly in recent years
- Single-molecule counting applied to the study of GPCR oligomerization
These details are often challenging to quantitatively assess yet are essential for our understanding
- Novel Therapies for Cardiometabolic Disease: Recent Findings in Studies with Hormone...
greatly impact the treatment of CVD with unprecedented benefits which will be revealed in the next years
- Successful prednisolone or calcimimetic treatment of acquired hypocalciuric hypercalcemia caused...
AHH who shared characteristics with the 2 cases we previously reported as follows: (a) elderly (74-87 years
- Developing the Cannabinoid Receptor 2 (CB2) pharmacopoeia: past, present, and future
2022 "Cannabinoid Receptor 2 (CB2) is a G protein-coupled receptor (GPCR) with considerable, though as yet
- Developing the Cannabinoid Receptor 2 (CB2) pharmacopeia: past, present, and future
2022 "Cannabinoid Receptor 2 (CB2) is a G protein-coupled receptor (GPCR) with considerable, though as yet
- TRPM3 in the eye and in the nervous system - from new findings to novel mechanisms
variants that result from alternative splicing have been identified and the majority of these isoforms are yet
- GRK2 in cardiovascular disease and its potential as a therapeutic target
research, case numbers and overall mortality remain high and have trended upwards over the last few years
- Aβ peptides stabilize GPCRs in inactive form and trigger inverse agonism in Alzheimer's disease
Yet, despite this upregulation, associated physiological effects are not observed in AD patients.
- RGS7-ATF3-Tip60 Complex Promotes Hepatic Steatosis and Fibrosis by Directly Inducing TNFα
Aims: The pathophysiological mechanism(s) underlying non-alcoholic fatty liver disease (NAFLD) have yet