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119 items found for "Lipid metabolism"
- 📰 GPCR Weekly News, February 26 to March 3, 2024
GPCR Partnered Events April 22 - 23, 2024 | Endocrine Metabolic GPCRs Join the Endocrine Metabolic GPCRs in GPCR Research Cryo-electron microscopy for GPCR research and drug discovery in endocrinology and metabolism
- 📰 GPCR Weekly News, February 5 to 11, 2024
April 22 - 23, 2024 | Endocrine Metabolic GPCRs Join our Founder Dr. Yamina Berchiche at the Endocrine Metabolic GPCRs event in Birmingham, UK, on April 22-23, 2024. alters G-protein coupled receptor-mediated vasocontraction in rat coronary arteries GPCRs involved in metabolic
- GPCR/endocytosis/ERK signaling/S2R is involved in the regulation of the internalization...
) exhibits a series of cell-activating properties, such as promoting cell spreading, migration, and metabolic reduced the uptake, which was accompanied by the nullification of the promoting effect of F-Hst1 on cell metabolic
- 📰 GPCR Weekly News, February 12 to 18, 2024
April 22 - 23, 2024 | Endocrine Metabolic GPCRs Join Dr. GPCR founder Dr. Yamina Berchiche at the Endocrine Metabolic GPCRs event in Birmingham, UK, on April 22-23, 2024. pathophysiology Common changes in rat cortical gene expression after antidepressant drug treatment: impacts on metabolism
- Novo Nordisk moves to strengthen obesity efforts
work with EraCal to identify novel drug targets relevant for food intake regulation and additional metabolic
- 📰 GPCR Weekly News, January 15 to 21, 2024
April 22 - 23, 2024 | Endocrine Metabolic GPCRs Join Dr. GPCR at the Endocrine Metabolic GPCRs Summit on April 22-23, 2024, in Birmingham, UK. Dr. Updates in GPCR Research G-Protein Coupled Receptor Gpr-1 Is Important for the Growth and Nutritional Metabolism
- Ono Enters into Collaboration Agreement with Domain Therapeutics and Université de Montréal for ...
Canada; “UdM”), to discover novel small molecules targeting G-Protein Coupled Receptors (GPCRs) in a metabolic
- Cell Surface Calcium-Sensing Receptor Heterodimers: Mutant Gene Dosage Affects Ca 2+ Sensing but...
It plays a key role in the regulation of human calcium and thus mineral metabolism. heterozygous or homozygous inactivating mutations, which have implications for disorders of calcium metabolism
- Verily links up with Sosei Heptares for GPCR drug discovery
drugs in treating a range of health conditions, from cancer and genetic disorders to inflammation and metabolic
- 📰 GPCR Weekly News, January 1 to 7, 2024
CXCL14 activates MAS-related G protein-coupled receptor MRGPRX2 and its putative mouse ortholog MRGPRB2 Metabolite-sensing American Physiology Summit April 5 - 10, 2024 | AACR Annual Meeting April 22 - 23, 2024 | Endocrine Metabolic
- 📰 GPCR Weekly News, March 18 to 24, 2024
GPCR Partnered Events April 22 - 23, 2024 | Endocrine Metabolic GPCRs Join the Endocrine Metabolic GPCRs
- Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1
October 2022 "Lysosomes coordinate cellular metabolism and growth upon sensing of essential nutrients
- 📰 GPCR Weekly News, May 27 to June 2, 2024
G-protein activation via phosphorylation mediated non-canonical pathway GPCR Screening Reveals that the Metabolite for stabilization Cryo-electron microscopy for GPCR research and drug discovery in endocrinology and metabolism
- Therapeutic validation of an orphan G protein-coupled receptor: The case of GPR84
emerging interest in defining if agonists of GPR84 might find utility in conditions in which regulation of metabolism
- 📰 GPCR Weekly News, March 4 to 10, 2024
GPCR Partnered Events April 22 - 23, 2024 | Endocrine Metabolic GPCRs Join the Endocrine Metabolic GPCRs
- Discovery and In Vivo Evaluation of ACT-660602: A Potent and Selective Antagonist of the Chemokine..
compound with high biological potency in inhibiting cell migration together with improvements of the metabolic
- Orion Announces The Rapid Lead Optimization Of Ob-004 - A Ccr2 Antagonist
The CCL2/CCR2 pathway plays an important role in oncology, inflammatory, metabolic, and neurological
- C3aR plays both sides in regulating resistance to bacterial infections
roles for C3aR in regulating innate immune cell inflammatory state, antimicrobial killing capacity, and metabolism
- 📰 GPCR Weekly News, June 17 to 23, 2024
restrains apoptosis in colorectal cancer through disrupting TRAF6-TAB2-TAK1-JNK/p38 MAPK signaling Metallo-protease an Entrepreneur Of The Year® 2024 Pacific Southwest Award Winner Monlunabant by Inversago Pharma for Metabolic
- RAB-Symposium - Regulatory Autoantibodies Targeting GPCRs. September 15-16, 2022. Lübeck, Germany...
with a focus on small molecules and monoclonal antibodies for the treatment of cancer, infections, metabolic
- 📰 GPCR Weekly News, December 11 to 17, 2023
GPCR Activation and Signaling GPCR screening reveals that the metabolite receptor HCAR3 regulates epithelial American Physiology Summit April 5 - 10, 2024 | AACR Annual Meeting April 22 - 23, 2024 | Endocrine Metabolic
- Biased Agonism at the GLP-1 Receptor: A Pathway to Improved Therapeutic Outcomes
The GLP-1R, a class B1 GPCR, is integral to metabolic regulation, particularly in glucose homeostasis biased agonism at the GLP-1R represents a promising strategy for optimizing therapeutic outcomes in metabolic Cell Metab, 2018. 27 (4): p. 740-756. 3.
- Ode to GPCRs
the various hormones, including adrenaline secreted from the anterior pituitary lobe, in carbohydrate metabolism 39] In their work, the duo further investigated the work of Gerty Cori and Carl Cori on carbohydrate metabolism Our understanding of how various factors, such as lipid composition, osmotic stress, and allosteric ligands
- 📰 GPCR Weekly News, March 11 to 17, 2024
GPCR Partnered Events April 22 - 23, 2024 | Endocrine Metabolic GPCRs Join the Endocrine Metabolic GPCRs
- GPCR Signaling and mTORC1 Regulation
target of rapamycin (mTOR) senses upstream stimuli to regulate numerous cellular functions such as metabolism
- Functional modulation of PTH1R activation and signaling by RAMP2
hormone 1 receptor (PTH1R), a class B GPCR and an important modulator of mineral ion homeostasis and bone metabolism
- Transformative GPCR Insights: Unleash New Horizons in Science | Sep 9 - 15, 2024
GPCRs in Cardiology, Endocrinology, and Taste CRTC1 in Mc4r-expressing cells is required for peripheral metabolism in Oncology and Immunology The power of many: Multilevel targeting of representative chemokine and metabolite
- ADGRL3 genomic variation implicated in neurogenesis and ADHD links functional effects to the...
mutations in the ADGLR3 gene disrupt the standard and wild ADGRL3 structure, most likely affecting its metabolic