Search Results
119 items found for "Lumpy skin disease"
- Ep 52 with Dr. Benjamin Myers
tiny antenna-shaped structure at the cell surface with critical links to development, physiology, and disease
- Developing a PROTAC to Degrade the Constitutively Active Onco-GPCR in Uveal Melanoma
She is currently working to understand the signaling and degradation of GPCRs in disease states to help
- Ep 64 with Dylan Eiger
his research on biased agonism at GPCRs with a particular focus on the treatment of cardiovascular disease
- Receptor autoantibodies: Associations with cardiac markers, histology, and function in human non-ischaemic heart failure
ambiguous reports on incidences of GPCR autoantibodies, spurious correlations of autoantibody levels with disease they are correlated poorly or even inversely to haemodynamic, metabolic, and functional markers of disease
- Abstract Submission Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
categories max) Abstract categories Signaling Trafficking Metabolism Structure and Bioinformatics Health and Disease
- Ep 63 with Dr. Khaled Abdelrahman
in a sex-selective manner and how this can influence drug discovery in the area of neurodegenerative diseases
- Ep 59 with Dr. Nicola J. Smith
a track record in exploring GPCR structure-function relationships in the context of cardiovascular disease
- GPCR Retreat Logo Contest | Dr. GPCR Ecosystem
processes, making them a focal point of scientific research with implications for human health and disease
- Ep 107 with Dr. Roger Sunahara
studies to address the functional role of these dramatic conformational changes and the relationship to disease continues to engineer the enzyme to optimize its potential as a treatment for cocaine abuse, a debilitating disease
- Ep 141 with Dr Tobi Langenhan
physiological and pharmacological principles that underlie the workings of adhesion GPCRs in health and disease
- Ep 101 with Dr Caron Tribute Part 2
neurotransmitters and how they might underlie brain and behavior disorders such as schizophrenia, Parkinson's disease
- Ep 62 with Dr. Sai Prasad Pydi
Jurgen Wess’s lab at the National Institute of Diabetes, Digestive and Kidney Diseases (NIDDK) - NIH,
- Dopamine-Mediated Motor Recovery after Ischemic Stroke
development of new therapeutic interventions for the alleviation of L-DOPA-induced dyskinesia in Parkinson’s Disease
- A positive Allosteric Modulator of M1 Acetylcholine Receptors Improves Cognitive Deficits in Male and Female Alzheimer’s Mice
in a sex-selective manner and how this can influence drug discovery in the area of neurodegenerative diseases
- Ep 18 with Dr. Yamina Berchiche
and pharmacology can provide new opportunities to improve our understanding of human physiology and disease
- GPR37 promotes colorectal cancer against ferroptosis by reprogramming lipid metabolism via p38-SCD1 axis
Colorectal cancer (CRC) is a prevalent malignant tumor worldwide, leading to significant morbidity and disease
- Ep 92 with Dr. Stephane Angers
of growth factors and their signaling mechanisms in development, adult tissue homeostasis, and human diseases
- Ep 100 with Dr Caron Tribute Part 1
neurotransmitters and how they might underlie brain and behavior disorders such as schizophrenia, Parkinson's disease
- Ep 84 with Rosie Dawaliby
Confo Therapeutics ) as a team and project leader for antibody discovery for metabolic and inflammatory diseases
- Chemokine N-terminal-derived peptides differentially regulate signaling by the receptors CCR1 and CCR5
CCR1 and CCR5 Published date November 23, 2023 Abstract "Inflammatory chemokines are often elevated in disease
- Ep 150 with Dr GPCR Team
Sachdev is an early career researcher in the National Institute of Diabetes and Digestive and Kidney Diseases he aims to apply this knowledge to develop novel chemical treatments for neuronal and cardiovascular diseases
- Chemoattractant receptor signaling in humoral immunity
humoral immunity and discuss the potential of the COMMD3/8 complex as a therapeutic target for autoimmune diseases
- Ep 102 with Dr Caron Tribute Part 3
neurotransmitters and how they might underlie brain and behavior disorders such as schizophrenia, Parkinson's disease
- Stable Binding of Full-Length Chemerin is Driven by Negative Charges in the CMKLR1 N-terminus
This may help to develop more potent ligands for the treatment of inflammatory related diseases."
- Ep 148 with Dr Arthur Christopoulos
, molecular and cellular pharmacology, medicinal chemistry, and preclinical models of behaviour and disease work has been applied to studies encompassing neurological and psychiatric disorders, cardiovascular disease Lastly, they discussed the progress of new drugs targeting specific receptors for various diseases, with
- Ep 149 with Dr Arthur Christopoulos
, molecular and cellular pharmacology, medicinal chemistry, and preclinical models of behaviour and disease work has been applied to studies encompassing neurological and psychiatric disorders, cardiovascular disease Lastly, they discussed the progress of new drugs targeting specific receptors for various diseases, with
- A GPCR-neuropeptide axis dampens hyperactive neutrophils by promoting an alternative-like polarization during bacterial infection
expressed NPFF, these findings could have broad implications in various infectious and inflammatory diseases
- GPCR Retreat 2023 - Part I
laboratory has gained valuable insights into the genetic basis and pathophysiology of lymphatic vascular disease , preeclampsia and sex-dependent cardiovascular disease.