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66 items found for "Mark Connor"
- Extracellular signal-regulated kinases – a potential pathway for GPCR-targeted drug discovery
Extracellular signal-regulated kinases (ERK), a subset of the mitogen-activated protein kinase (MAPK) Spatiotemporal regulation of the p42/p44 MAPK pathway. Biology of the Cell, 93(1‐2), 71-79.
- GB83, an Agonist of PAR2 with a Unique Mechanism of Action Distinct from Trypsin and PAR2-AP
of PAR2 by GB83 markedly elicited an increase in intracellular calcium levels and phosphorylation of MAPKs
- Increased Anxiety-like Behaviors in Adgra1-/- Male But Not Female Mice are Attributable to...
not female mice exhibited elevated anxiety levels in the open field, elevated plus maze, and light-dark
- GASP1 enhances malignant phenotypes of breast cancer cells and decreases their response to...
ubiquitin E3 ligase MDM2, thereby activating its downstream signaling pathways such as NF-κB, PI3K/AKT, and MAPK
- Regulation of rod photoreceptor function by farnesylated G-protein γ-subunits
In all dark-adapted transgenic lines, Gαt1 was targeted to the outer segments, reversing its diffuse
- HBx induces hepatocellular carcinogenesis through ARRB1-mediated autophagy to drive the G 1/S cycle
light chain 3 beta; MKI67: marker of proliferation Ki-67; MTOR: mechanistic target of rapamycin kinase; MAPK
- 📰 GPCR Weekly News - January 9 to 15, 2023
The molecular associations in clathrin-coated pit regulate β-arrestin-mediated MAPK signaling downstream
- 📰 GPCR Weekly News, January 15 to 21, 2024
G-Protein Coupled Receptor Gpr-1 Is Important for the Growth and Nutritional Metabolism of an Invasive Bark
- Chemokine receptor-targeted drug discovery: progress and challenges
and induces different patterns of receptor recycling where CCR5 recycles back to the cell surface (Mack
- 📰 GPCR Weekly News, June 17 to 23, 2024
protein signaling 16 restrains apoptosis in colorectal cancer through disrupting TRAF6-TAB2-TAK1-JNK/p38 MAPK