trial Salipro Biotech is attending the 3rd Advanced Therapy Showcase in Tokyo, Japan, organized by LINK-J

Mechanism of Action and Target Engagement Novo Nordisk's GLP-1 for Type II diabetes approved for first-line

Classified GPCR News from April 1st to 7th, 2024 GPCR Activation and Signaling GPRASP1 loss-of-function links

While these small protein GPCRs are valuable drug targets linked to serious diseases, many remain undrugged The remaining non-sensory receptors, with functions more readily linked to pathology, are currently the This leads to strikingly long in vitro receptor occupancy durations (at least seven days), meaning that Figure 5: In an in vitro functional signaling assay on a human monocytic cell line, OB-004 demonstrated

The Neuromedin U system: pharmacological implications for the treatment of obesity and binge eating behavior

functions, such as sensory perception, reproduction, development, growth, metabolism, and are also linked

immunodeficiency G protein-coupled receptors: A target for microbial metabolites and a mechanistic link

Immunology [1,2,4]Triazolo[1,5-c]pyrimidines as Tools to Investigate A3 Adenosine Receptors in Cancer Cell Lines Severity of neurological long-COVID symptoms correlates with increased level of autoantibodies targeting

You can consult the article at the following link: https://www.ecosystem.drgpcr.com/structural-and-molecular-insights-into-gpcr-function

functions as a feeding-state-dependent regulatory metabolite to counter pro-inflammatory signaling linked

Study Completes Recruitment of Patients Sanyou Bio's Evolution of Bioprocess Enhancement for CHO Cell Lines

News Novartis Lutathera® significantly reduced risk of disease progression or death by 72% as first-line

exchange factor RIC-8 regulates cilia morphogenesis in Caenorhabditis elegans sensory neurons CaSR links

To know more about this report check this link. References: Jin, B. C., Ring, A.

1984 (Cerione et al. 1984), where reconstitution of purified β2-adrenergic receptors from guinea pig lung different ligands inducing unique GPCR conformations that selectively activate specific cellular outcomes linked

Functional Assessment of Cancer-Linked Mutations in Sensitive Regions of Regulators of G Protein Signaling

This week's highlight includes congrats to: Junyi Liang, Niña Caculitan, and Adam W Smith for their research

Structurally they characterize by a long extracellular region of adhesion-like domains which modulate Ping, Y.-Q., et al., Structural basis for the tethered peptide activation of adhesion GPCRs. Qian, Y., Ma, Z., Liu, C., Li, X., Zhu, X., Wang, N., Xu, Z., Xia, R., Liang, J., Duan, Y., Yin, H.,

N-terminus to the extracellular tip of the seventh transmembrane helix (TM7) near ECL3, while the other links