top of page

Search Results

204 items found for "Specialized pro-resolving mediators"

  • Engineered synaptic tools reveal localized cAMP signaling in synapse assembly

    targeting molecules, that enable localized perturbations of cAMP signaling in developing postsynaptic specializations that postsynaptic latrophilin adhesion-GPCRs drive synapse formation and produce cAMP, we suggest that spatially restricted postsynaptic cAMP signals organize assembly of postsynaptic specializations during synapse

  • 📰 GPCR Weekly Buzz: Exciting Schedule Shifts for Principles of Pharmacology I & II | August 12-18, 2024

    signaling in humoral immunity Methods & Updates in GPCR Research Probing PAC1 receptor activation across species Epitope Tagging of Endogenous G-Protein-Coupled Receptors in Drosophila Measuring G protein activation by spectrally resolved imaging fluorescence fluctuation spectroscopy Structural and Molecular Insights into GPCR Function | 9th GPCRs in Medicinal Chemistry October 17, 2024 | Unprecedented fragment-based screening using Spectral

  • Exploring the Breakthroughs in GPCR Research

    receptor 4 as a regulator of food and water intake The tick Ixodes scapularis has five different GPCRs specifically Structural and Molecular Insights into GPCR Function Structural Mass Spectrometry Captures Residue-Resolved

  • 📰 GPCR Buzz: August 5-11, 2024 | Top Highlights from DrGPCR University!

    Access to a Private Community Certificate of Participation for each course Don’t miss out—grab this special modulator of β2-adrenergic receptors GPCRs in Neuroscience In-silico predicted mouse melanopsins with blue spectral subcellular signaling Striatal serotonin release signals reward value Ciliary length variations impact cilia-mediated | 9th GPCRs in Medicinal Chemistry October 17, 2024 | Unprecedented fragment-based screening using Spectral

  • 📰 GPCR Weekly News, April 17 to 23, 2023

    Regulation of the pro-inflammatory G protein-coupled receptor GPR84.

  • Unlock the Future of GPCR Science: Breakthroughs and Courses Await | Sep 2 - Sep 8, 2024

    Potnick, to our Medicinal Chemistry group Call for GPCR Papers Emerging Voices in GPCR Biology in Special | 9th GPCRs in Medicinal Chemistry October 17, 2024 | Unprecedented fragment-based screening using Spectral conformational dynamics and phosphorylated receptor interaction Early Events in β2AR Dimer Dynamics Mediated Protein-Dependent Properties for the Sweet Taste Heterodimer, TAS1R2/1R3 GPCRs in Neuroscience GPCR-Mediated

  • Molecular targets of psychedelic-induced plasticity

    A special emphasis is placed on knowledge gaps, challenges, and limitations to evaluate the underpinnings

  • Discover the Hottest GPCR News of the Week: Oct 7-13, 2024!

    Announces Conference Call and Webcast of Third Quarter 2024 Financial Results Novel full MC4 receptor-specific Emerging Voices in GPCR Biology in Special Issue of Molecular Pharmacology GPCR Events, Meetings, and Webinars October 17, 2024 | Unprecedented fragment-based screening using Spectral Shift for GPCRs October GPCR mechanosensing   Postdoctoral Position GPCR Activation and Signaling Diverse pathways in GPCR-mediated

  • Learn more about Neurocrine Biosciences with their new video

    Neurocrine Biosciences story puts into words what makes the work and people at Neurocrine Biosciences so special

  • Domain Therapeutics Raises $42m Series A Financing

    immuno-oncology programs STRASBOURG, France & MONTREAL- Domain Therapeutics, a biopharmaceutical company specializing

  • Domain Therapeutics and Explicyte enter partnership agreement in immuno-oncology

    Strasbourg and Bordeaux, France, March 10, 2022 – Domain Therapeutics, a biopharmaceutical company specializing

  • GPCR Buzz of the Week | Sep 23 - 29, 2024

    Emerging Voices in GPCR Biology in Special Issue of Molecular Pharmacology GPCR Events, Meetings, and | 9th GPCRs in Medicinal Chemistry October 17, 2024 | Unprecedented fragment-based screening using Spectral Cell Migration GPCR Activation and Signaling Subcellular activation of β-adrenergic receptors using a spatially Modulates Store-Operated Calcium Entry in the Lung Endothelium: A Novel Mechanism Controlling NFAT-Mediated receptor transcripts in human immune cells and platelets Methods & Updates in GPCR Research Simultaneous spectral

  • 📢 Early Bird Registration Ends Tomorrow! | Sep 16 - 22, 2024

    Emerging Voices in GPCR Biology in Special Issue of Molecular Pharmacology GPCR Events, Meetings, and | 9th GPCRs in Medicinal Chemistry October 17, 2024 | Unprecedented fragment-based screening using Spectral Dissociation between the anti-allodynic effects of fingolimod (FTY720) and desensitization of S1P1 receptor-mediated

  • An overview of the compartmentalized GPCR Signaling: Relevance and Implications

    The cellular context is crucial for understanding the diverse signaling outcomes mediated by different The localization of GPCRs to specific intracellular compartments dictates the spatial and temporal dynamics processes, including phospholipase C epsilon (PLCε)-dependent signaling and transcriptional responses mediated This may involve the development of specialized delivery vehicles, such as nanoparticles or liposomes Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular

  • 📰 GPCR Weekly News, July 31 to August 6, 2023

    using molecular dynamic simulations Kinetic insights into agonist-dependent signalling bias at the pro-inflammatory

  • Hop in the Time Machine with GPCR: Unraveling the Future of Research! ⦿ Nov 24 - Dec 1, 2024

    GPCR University 🎥 Recorded GPCR Courses and Symposia / Summit 💲 Special Pricing on GPCR courses carcinoma RNAi library screening reveals Gβ1, Casein Kinase 2 and ICAP-1 as novel regulators of LFA-1-mediated

  • G protein-coupled receptors that influence lifespan of human and animal models

    whose activity has been shown to affect the lifespan of animal and human models, and in which we put a special

  • 📰 GPCR Weekly News, January 30 to February 5, 2023

    Genetic code expansion to enable site-specific bioorthogonal labeling of functional G protein-coupled Methods & Updates in GPCR Research Deep-Learning-Enhanced Diffusion Imaging Assay for Resolving Local-Density Scientist/Senior Scientist (Research Software Engineer) Senior Scientist – Native Mass Spectrometry Speculative Applications (Protein Biochemistry) Speculative Applications (Mass Spectrometry) Speculative Applications

  • Regulator of G Protein Signaling 20 Correlates with Long Intergenic Non-Coding RNA (lincRNAs)...

    we investigated the role of RGS20 as a potential prognostic marker in 28 different cancer types with special

  • GPCR Updates: Celebrating Breakthroughs, New Course Launches Soon, and Exclusive Discounts! | Aug 26 - Sep 1, 2024

    Special Offer for Scientists who work and live in developing countries If you live and work in a developing ADS024 a Novel Oral Agent for Neuroinflammation Call for GPCR Papers Emerging Voices in GPCR Biology in Special | 9th GPCRs in Medicinal Chemistry October 17, 2024 | Unprecedented fragment-based screening using Spectral

  • 📰 GPCR Weekly News, March 4 to 10, 2024

    into the Classified GPCR News from March 4th to 10th, 2024 GPCR Activation and Signaling Glu1022.53-Mediated of binding pathways and two distinct high-affinity sites for succinate in succinate receptor 1/GPR91 Specific Chemicals Activate G Protein-Coupled Receptors GPCRs in Neuroscience A M1 muscarinic acetylcholine receptor-specific with selective and nonselective antagonists studied by NMR spectroscopy Up-regulation of GPR139 in the medial Exhibition June 2 - 7, 2024 | Chemotactic Cytokines June 9 - 14, 2024 | 2024 Phosphorylation and G-Protein Mediated

  • 📢 GPCR Update: August 19-25, 2024 | Thrilling Announcement: New Pharmacology Course Dates & Exclusive Discounts Inside!

    Partnered Schizophrenia Candidate NBI-1117568 Call for GPCR Papers NEW Emerging Voices in GPCR Biology in Special | 9th GPCRs in Medicinal Chemistry October 17, 2024 | Unprecedented fragment-based screening using Spectral

  • Unveiling GPCR Priming: The Hidden Synergy in Cellular Signalling

    These receptors typically engage specific G protein subtypes, such as Gs, Gi/o, Gq/11, and G12/13, at modulation (SPASM) technique to show that Gq proteins could bolster Gs dependent-β2-adrenergic receptor-mediated cAMP signalling, while Gs proteins similarly enhanced Gq dependent-vasopressin receptor-mediated IP1 Overall, the increased calcium signalling was attributed to the release of ATP via β2AR-Gs mediated activation However, IP1 signalling through the non-cognate Gq was not important for the increased β2AR-Gs-mediated

  • Embark on a GPCR Adventure: Your Weekly Research Expedition! | Oct 21-27, 2024

    Emerging Voices in GPCR Biology in Special Issue of Molecular Pharmacology GPCR Events, Meetings, and GPCRs in Oncology and Immunology Characterization, expressional and evolutionary analysis of five fish-specific

  • Regulation of pulmonary surfactant by the adhesion GPCR GPR116/ADGRF5 requires a tethered agonist...

    2022 Regulation of pulmonary surfactant by the adhesion GPCR GPR116/ADGRF5 requires a tethered agonist-mediated To examine this hypothesis, we characterized tethered agonist-mediated activation of GPR116 in vitro mutant phenocopies the pulmonary phenotype of GPR116 knock-out mice, demonstrating that tethered agonist-mediated Using site-directed mutagenesis and species-swapping approaches, we identified key conserved amino acids We further highlight residues in transmembrane 7 (TM7) that mediate stronger signaling in mouse versus

  • 📰 GPCR Weekly News

    Receptor Agonist PF-07081532 into Phase 2 Clinical Trials for Treating Type 2 Diabetes and Obesity Special

  • 📰 GPCR Weekly News, October 23 to 29, 2023

    Plus, don't forget to ask for your special treat.

  • 📰 GPCR Weekly News, December 18 to 31, 2023

    biological control Larixol is not an inhibitor of Gαi containing G proteins and lacks effect on signaling mediated expressed formyl peptide receptors GPCRs in Cardiology, Endocrinology, and Taste Beta cell primary cilia mediate dopamine receptors Targeting CB2R in astrocytes for Parkinson's disease therapy: unraveling the Foxg1-mediated neuroprotective mechanism through autophagy-mediated NLRP3 degradation Methods & Updates in GPCR Research Exhibition June 2 - 7, 2024 | Chemotactic Cytokines June 9 - 14, 2024 | 2024 Phosphorylation and G-Protein Mediated

Powered by


All Rights Reserved © 2020 - 2024

Dr. GPCR CORP is a 501(c)(3) non profit organization

  • Facebook
  • Twitter
  • LinkedIn
  • Instagram
bottom of page