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124 items found for "drug discovery"
- G protein-coupled receptor-mediated signaling of immunomodulation in tumor progression
Finally, we review the progress of clinical trials of GPCR-targeted drugs for cancer treatment, which Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- Ep 82 with Dr. Lauren M. Slosky
Lauren Slosky is an Assistant Professor in the Department of Pharmacology and a member of the Medical Discovery within the University of Minnesota’s Medical School to advance research and treatment in the field of drug
- Classified News | Dr. GPCR Ecosystem
GPCR Route 66+ project Read More October 1, 2022 GPCRs: Signal Transduction Read More GPCR Binders, Drugs the Receptor-Associated G Proteins in Two Lepidopteran Species Read More October 1, 2024 Target-based discovery
- GPCRs and fibroblast heterogeneity in fibroblast-associated diseases
About one-third of the commercially available drugs for various diseases target the GPCRs. Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- Structural Basis for the Recognition of GPRC5D by Talquetamab, a Bispecific Antibody for Multiple Myeloma
Talquetamab, a Food and Drug Administration-approved T-cell-directing bispecific antibody developed for Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- Interaction with the cell adhesion molecule NEGR1 affects mGluR5 cell signalling
the study of the mechanisms involved in neurodegeneration and the characterization of neuroprotective drugs These drugs were shown to be very effective to rescue the cell death observed in a mouse model of Huntington
- LPA1-mediated inhibition of CXCR4 attenuates CXCL12-induced signaling and cell migration
This discovery provides crucial insights into a valuable regulatory mechanism of CXCR4 through heteromerization Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- Comparative Analysis of the GNAI Family Genes in Glioblastoma through Transcriptomics and Single-Cell Technologies
treatment of GBM is challenging due to the presence of the blood-brain barrier (BBB), which hinders drug Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- Ep 76 with Steve McCloskey
Scientists and Engineers working at the nanoscale, specifically protein engineering and small molecule drug
- Ep 79 with Dr. Graeme Milligan
and identification of small molecule regulators of these proteins, and progressing such ligands in drug
- Ep 157 with Dr. Nagarajan Vaidehi
molecular dynamics simulation methods with emphasis on application to G-protein coupled receptors and drug
- Ep 46 with Dr Gunnar Schulte
ultimate aim is to use the new knowledge to find, create and optimize Frizzled-targeting small molecule drugs
- Itaconate in host inflammation and defense
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- Olfactory Receptors and Tumorigenesis: Implications for Diagnosis and Targeted Therapy
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- Noval insights and therapeutic strategies for tumor-induced kidney pathologies
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- Chemokine N-terminal-derived peptides differentially regulate signaling by the receptors CCR1 and CCR5
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- Ep 89 with Dr. Patrick Sexton
of the International Union of Basic and Clinical Pharmacology Committee on Receptor Nomenclature and Drug
- GprC of the nematode-trapping fungus Arthrobotrys flagrans activates mitochondria and reprograms fungal cells for nematode hunting
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- Chemoattractant receptor signaling in humoral immunity
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- Aberrant hormone receptors regulate a wide spectrum of endocrine tumors
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- Ep 104 with Dr. Raul Gainetdinov
of the International Union of Basic and Clinical Pharmacology Committee on Receptor Nomenclature and Drug
- Targeting adenosine signaling for immuno-oncology
Dr Stagg has served as an expert consultant in the development of adenosine-targeting drugs, several
- Autocrine proteinase-activated receptor signaling in PC3 prostate cancer cells
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- G protein-coupled receptors related to autoimmunity in postural orthostatic tachycardia syndrome
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- A GPCR-neuropeptide axis dampens hyperactive neutrophils by promoting an alternative-like polarization during bacterial infection
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- Atypical Structure and Function of Typical Chemokine Receptors
These mice can then be used to test dietary regimens, drugs, and adenoviral gene therapies for their
- A virally encoded GPCR drives glioblastoma through feed-forward activation of the SK1-S1P1 signaling axis
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- CCL5-producing migratory dendritic cells guide CCR5+ monocytes into the draining lymph nodes
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
