My group studies the spatiotemporal dynamics of atypical inflammation and the control of disease progression

and clinical pharmacology as scientist or PI in neonatal lupus, Cardiomyopathy, hypertension, chagas disease

Sachdev is an early career researcher in the National Institute of Diabetes and Digestive and Kidney Diseases

findings propose a therapeutic potential in combined CXCR4 and LPA1 inhibitors for cancer and inflammatory diseases receptor 4 , Chemotaxis , G protein-coupled receptor , GPCR heteromer , GPCR signaling , Inflammatory disease

In 1983, he joined the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) at the

tiny antenna-shaped structure at the cell surface with critical links to development, physiology, and disease

She is currently working to understand the signaling and degradation of GPCRs in disease states to help

his research on biased agonism at GPCRs with a particular focus on the treatment of cardiovascular disease

ambiguous reports on incidences of GPCR autoantibodies, spurious correlations of autoantibody levels with disease they are correlated poorly or even inversely to haemodynamic, metabolic, and functional markers of disease

categories max) Abstract categories Signaling Trafficking Metabolism Structure and Bioinformatics Health and Disease

in a sex-selective manner and how this can influence drug discovery in the area of neurodegenerative diseases

a track record in exploring GPCR structure-function relationships in the context of cardiovascular disease

processes, making them a focal point of scientific research with implications for human health and disease

studies to address the functional role of these dramatic conformational changes and the relationship to disease continues to engineer the enzyme to optimize its potential as a treatment for cocaine abuse, a debilitating disease

physiological and pharmacological principles that underlie the workings of adhesion GPCRs in health and disease

neurotransmitters and how they might underlie brain and behavior disorders such as schizophrenia, Parkinson's disease

Jurgen Wess’s lab at the National Institute of Diabetes, Digestive and Kidney Diseases (NIDDK) - NIH,

development of new therapeutic interventions for the alleviation of L-DOPA-induced dyskinesia in Parkinson’s Disease

awarded the Young Investigator Transdisciplinary Research Award (2022-2023 and 2023-2024) from the bone

in a sex-selective manner and how this can influence drug discovery in the area of neurodegenerative diseases

and pharmacology can provide new opportunities to improve our understanding of human physiology and disease

Colorectal cancer (CRC) is a prevalent malignant tumor worldwide, leading to significant morbidity and disease

of growth factors and their signaling mechanisms in development, adult tissue homeostasis, and human diseases

neurotransmitters and how they might underlie brain and behavior disorders such as schizophrenia, Parkinson's disease

Confo Therapeutics ) as a team and project leader for antibody discovery for metabolic and inflammatory diseases

CCR1 and CCR5 Published date November 23, 2023 Abstract "Inflammatory chemokines are often elevated in disease In contrast, none of the peptides generated a signal on CCR5, but a CCL3-derived tetrapeptide was a positive

Sachdev is an early career researcher in the National Institute of Diabetes and Digestive and Kidney Diseases he aims to apply this knowledge to develop novel chemical treatments for neuronal and cardiovascular diseases

humoral immunity and discuss the potential of the COMMD3/8 complex as a therapeutic target for autoimmune diseases