November 2022 "Recently determined structures of class C G protein-coupled receptors (GPCRs) revealed

Lysophosphatidic acids (LPAs) are bioactive phospholipids implicated in a wide range of cellular activities

Point mutations are in the C-tail of PAR4 PH-binding domain; F347 L and D349A, but not E346A, abrogate

C. Burger , Arthur Christopoulos , David M. Crinetics Pharmaceuticals Announces September 2024 Inducement Grants Under Nasdaq Listing Rule 5635(c)

(trans) function of the Adhesion GPCR Latrophilin-1 controls multiple processes in reproduction of C. (trans) function of the Adhesion GPCR Latrophilin-1 controls multiple processes in reproduction of C.

water flea Diaphanosoma celebensis genome, which were classified into five distinct classes (A, B, C,

some important clinical parameters such as alpha-fetoprotein and tumor grade in the HCC patients; (c)

Adhesion GPCRs GPR56 C-terminal fragment mediates signal received by N-terminal fragment of another adhesion Distal extracellular teneurin region (teneurin C-terminal associated peptide; TCAP) possesses independent

Award: Pioneering GPCR-Driven Immunotherapies in Cancer Treatment Structure Therapeutics Appoints Angus C. into GPCR Function Delineating the stepwise millisecond allosteric activation mechanism of the class C

Furthermore, after phosphorylating the C-terminal tail and intracellular loop 3 (ICL3) of NF-α1/CPE-5

interacts with β-arrestin2, and constitutively internalizes in a β-arrestin2-dependent manner (Gillilan, C.

While several gain-of-function mutations that lead to C-terminal truncations, frame shifts and point

Research Middle-Down Mass Spectrometry Reveals Activity-Modifying Phosphorylation Barcode in a Class C

RpGPCR41 is involved in the resistance of Rhopalosiphum padi to pyrethroids Discovering allatostatin type-C production drives rapid and sustained spiking in brainstem parabrachial neurons to suppress feeding The C-terminus

tissues is highly variable from more than 60 ORs in the testis and only a few ORs in the liver (Flegel C. known ligands for a variety of class I ORs, induce chemotactic behavior in human neutrophils (Geithe C.

., Liu, C., Li, X., Zhu, X., Wang, N., Xu, Z., Xia, R., Liang, J., Duan, Y., Yin, H., Xiong, Y., Zhang , A., Guo, C., Chen, Z., Huang, Z., & He, Y. (2022).

Structural and Molecular Insights into GPCR Function Lysophosphatidic acid, a simple phospholipid with

subunits required for the control of response to polystyrene nanoparticles in the range of μg/L in C.

., Macdonald, C. B., Mehrota, E., Grimes, P. R., ... & Manglik, A. (2024).

conformational states, which enable more efficient interactions between the GPCR and the cognate Gα C

Anionic phospholipids control mechanisms of GPCR-G protein recognition.

., & Tate, C. G. 2021). M. et al. 1999), while dual knockout is lethal (Schmid, C. L., & Bohn, L. M. 2009).

opioid addiction A FMRFamide-like neuropeptide FLP-12 signaling regulates head locomotive behaviors in C.

Neuroscience Early pheromone perception remodels neurodevelopment and accelerates neurodegeneration in adult C.

Structure Therapeutics Crinetics Pharmaceuticals Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)

News Crinetics Pharmaceuticals Announces August 2024 Inducement Grants Under Nasdaq Listing Rule 5635(c)

alleviates acetaminophen-induced liver injury in mice by inhibiting endoplasmic reticulum stress Two C-terminal

Crinetics Pharmaceuticals Announces November 2023 Inducement Grants Under Nasdaq Listing Rule 5635(c)