Search Results
111 items found for "Bryan L Roth"
- CB2 stimulation of adipose resident ILC2s orchestrates immune balance and ameliorates type 2 diabetes mellitus
CB2, a G-protein-coupled receptor (GPCR) and member of the endocannabinoid system, is expressed on both
- Ep 87 with Dr. Bianca Plouffe
Robert Lefkowitz , which led to the finding that both β-arrestin and G protein can simultaneously bind
- The landscape of cancer-rewired GPCR signaling axes
The expression of both receptor-ligand (or enzymes) partners improved patient stratification, suggesting
- Activation of orphan receptor GPR132 induces cell differentiation in acute myeloid leukemia
that genetic activation of the orphan GPCR GPR132 significantly induced cell differentiation of AML both Authors Chunyang Yi, Jiacheng He, Dan Huang, Yumiao Zhao, Chan Zhang, Xiyun Ye, Ying Huang, Ruth Nussinov
- Ep 43 with Dr. Stuart Maudsley
scientific journey with the award of the highly-valued Odysseus Program Type I Program Grant to work as both
- Ep 72 with Dr. Stuart Maudsley
scientific journey with the award of the highly-valued Odysseus Program Type I Program Grant to work as both
- Ep 78 with Dr. Stuart Maudsley
scientific journey with the award of the highly-valued Odysseus Program Type I Program Grant to work as both
- Ep 151 with Dr GPCR Board
Maria Waldhoer "I am a pharmacologist with a ~30 years background in academia and industry, working both After a well needed break from the grind, I am now a scientific/business consultant for clients both
- The Effect of Cancer-Associated Mutations on Ligand Binding and Receptor Function - A Case for the 5-HT2C Receptor
found that the affinity of the endogenous agonist serotonin (5-HT) and inverse agonist mesulergine were both
- Distinct Activation Mechanisms of CXCR4 and ACKR3 Revealed by Single-Molecule Analysis of their Conformational Landscapes
Published date June 20, 2024 Abstract "The canonical chemokine receptor CXCR4 and atypical receptor ACKR3 both
- SSTR2 positively associates with EGFR and predicts poor prognosis in nasopharyngeal carcinoma
of SSTR2, high expression of EGFR, and high coexpression of SSTR2 and EGFR had a poorer prognosis in both
- Ultrasensitive dose-response for asbestos cancer risk implied by new inflammation-mutation model
are thought to involve modes of action driven by mutations, cytotoxicity-associated inflammation, or both
- Esophageal and gastric cancer incidence trends in Golestan, Iran: An age-period-cohort analysis 2004 to 2018
Despite favorable trends, this population remains at high risk of both EC and GC.
- Proteogenomic landscape and clinical characterization of GH-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors
Classification by consensus clustering using both RNA sequencing and proteomics revealed many similarities
- Ep 36 with Dr. Michel Bouvier
He was also the head of both my Master’s and Ph.D. thesis committees.
- Context-dependent ciliary regulation of hedgehog pathway repression in tissue morphogenesis
In the hedgehog pathway, bifunctional GLI transcription factors generate both GLI-activators (GLI-A)
- Stimulation of ectopically expressed muscarinic receptors induces IFN-γ but suppresses IL-2 production by inhibiting activation of pAKT pathways in primary T cells
Importantly, costimulation of both muscarinic receptors plus the TCR even led to reduced IL-2 expression
- Session III | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
encoded reporter that facilitates visualization and quantification of aGPCR NTF-CTF separation events both the biological properties and signaling pathways activated by aGPCRs, investigating their roles in both
- Session VII | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
His research focuses on the relevance of aGPCRs in physiology and signaling using both in vitro and in
- Ep 142 with Dr Claudia Stäubert
Both agreed on the complexity of the topic, with Claudia concluding that diseases might first affect
- Ep 153 with Dr Jacek Mokrosiński
agreed, emphasizing the importance of mental preparation and embracing different social situations, both
- Ep 147 with Dr. Demet Araç
Both agreed that one should find work exciting and interesting, as life is too short to spend doing things
- Ep 144 with Dr Aurélien Rizk
They found it fascinating to integrate both fields and the potential it holds.
- Ep 146 with Dr Michael Feigin
They also discussed the challenges of the two-body problem, where both partners need to find suitable
- Content and Conduct Policy | Dr. GPCR Ecosystem
that online harassment is also illegal in many places and can have serious offline consequences for both
- Trademark Policy | Dr. GPCR Ecosystem
Except as set forth above, nothing herein grants or should be deemed to grant to you any right, title
- Posters | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Anxiety and memory function were tested using both male and female mice at 5-6 month of age.