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117 items found for "Cam Sinh Lu"
- Dr. GPCR Community Presentation | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Monserrat Avila Zozaya "My doctoral research was focused on investigating the cellular effects of missense lung
- Session III | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
adapted for the human aGPCRs CD97/ADGRE5 and Latrophilin/ADGRL3 and tested in HEK293T cells using a luciferase
- Session II | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Monserrat Avila Zozaya "My doctoral research was focused on investigating the cellular effects of missense lung Van Meir pursued postdoctoral work at the Ludwig Institute for Cancer Research in San Diego and joined
- Evolutionary diversity of CXCL16-CXCR6: Convergent substitutions and recurrent gene loss in sauropsids
CXCR6 deficiency lowers TRM cell numbers in the lungs and depletes ILC3s in the lamina propria, impairing Notably, single-cell RNA sequencing of the lung shows a drop in TRM cells in species with CXCR6 loss,
- Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
AM Coffee Break 10/23/2024 12:00 PM Session I 10/23/2024 01:00 PM Plenary Lecture 10/23/2024 2:00 PM Lunch AM Session IV 10/24/2024 12:00 PM Plenary Lecture II 10/24/2024 1:00 PM Posters 10/24/2024 2:00 PM Lunch Session VII 10/25/2024 12:00 PM Plenary Lecture III 10/25/2024 1:00 PM Session VIII 10/25/2024 2:00 PM Lunch
- CircFKBP5 Suppresses Apoptosis and Inflammation and Promotes Osteogenic Differentiation
The dual-luciferase reporter, RNA immunoprecipitation (RIP), and pull-down assays were used to confirm
- High Metabolite Concentrations in Portal Venous Blood as a Possible Mechanism for Microbiota Effects on the Immune System, and Western Diseases
Such pro-inflammatory immune cells may travel to tissues such as the brain, the lung, the kidney etc
- GPR15 expressed in T lymphocytes from RA patients is involved in leukocyte chemotaxis to the synovium
de Lourdes Ochoa-González, Martín Zapata-Zúñiga, Eduardo Mondragon-Marín, Edgar E Lara-Ramírez, Jose Luis
- Ep 25 with Dr. Annette Gilchrist
Annette Gilchrist About this episode Originally, Annette wanted to be a medical doctor but as luck has
- Expression prevalence and dynamics of GPCR somatostatin receptors 2 and 3 as cancer biomarkers beyond NET: a paired immunohistochemistry approach
Authors Mor Oron-Herman , David Kirmayer , Amelie Lupp , Stefan Schulz , Genady Kostenich , Michel Afargan
- Ep 33 with Dr. David E. Gloriam
In 2018 he joined the University of Copenhagen, where he has received an ERC Starting Grant, Lundbeck
- Inhibition of Relaxin Autocrine Signaling Confers Therapeutic Vulnerability in Ovarian Cancer
Washington University, the NIH and UCLA, he pursued his postdoctoral studies with Allan Bernstein at the Lunenfeld
- Natural carboxyterminal truncation of human CXCL10 attenuates glycosaminoglycan binding, CXCR3A signaling and lymphocyte chemotaxis, while retaining angiostatic activity
Authors Luna Dillemans , Karen Yu , Alexandra De Zutter , Sam Noppen , Mieke Gouwy , Nele Berghmans ,
- G protein-coupled estrogen receptor (GPER)/GPR30 forms a complex with the β1-adrenergic receptor, a membrane-associated guanylate kinase (MAGUK) scaffold protein, and protein kinase A anchoring protein (AKAP) 5 in MCF7 breast cancer cells
Julia Tutzauer , D Stephen Serafin , Tobias Schmidt , Björn Olde , Kathleen M Caron , L M Fredrik Leeb-Lundberg
- The landscape of cancer-rewired GPCR signaling axes
Authors Chakit Arora, Marin Matic, Luisa Bisceglia, Pierluigi Di Chiaro, Natalia De Oliveira Rosa, Francesco Carli, Lauren Clubb, Lorenzo Amir Nemati Fard, Giorgos Kargas, Giuseppe R Diaferia, Ranka Vukotic, Luana
- Ep 134 with Dr. Neil Grimsey
p38 signaling responses we are studying how atypical p38 controls the onset and pathogenesis of acute lung
- SSTR2 positively associates with EGFR and predicts poor prognosis in nasopharyngeal carcinoma
Authors Yue Xu , Zihan Quan , Yuting Zhan , Haihua Wang , Jiadi Luo , Weiyuan Wang , Songqing Fan Tags
- Ep 90 with Dr. Nariman Balenga
Druey at NIAID/NIH, where I characterized the role of RGS4 and RGS5 in airway hyperresponsiveness and lung fascinated by the multitude of processes that are regulated/dysregulated by GPCRs and RGS proteins in the lungs
- Ultrasensitive dose-response for asbestos cancer risk implied by new inflammation-mutation model
Mesothelioma and lung cancer induced by exposure to carcinogenic (e.g., certain asbestos) fibers in humans This theory is reviewed, implications of this theory are discussed in relation to mesothelioma and lung Author Kenneth T Bogen Tags Asbestos , Cytotoxicity , Inflammation , Lung cancer , Mesothelioma , Mutation
- Small-molecule targeting of GPCR-independent noncanonical G-protein signaling in cancer
DiGiacomo , Mariola Ferreras-Gutierrez , Shiva Dastjerdi , Alain Ibáñez de Opakua , Jong-Chan Park , Alex Luebbers
- Ep 100 with Dr Caron Tribute Part 1
Frederik Leeb-Lundberg (1984) Dr. Robert Lefkowitz (1973) Dr. Lee Limbird (1973) Dr.
- A GPCR-neuropeptide axis dampens hyperactive neutrophils by promoting an alternative-like polarization during bacterial infection
Mrgpra1-NPFF axis counter-regulated interferon (IFN) γ-mediated neutrophil polarization during acute lung Aishwarya Atakkatan , Felipe Andrade , Stephane Lajoie , Xinzhong Dong Tags IFNγ , Mrgpra1 GPCR , NPFF , lung
- Lactate receptor GPR81 drives breast cancer growth and invasiveness through regulation of ECM properties and Notch ligand DLL4
Authors Kathrine Lundø , Oksana Dmytriyeva , Louise Spøhr , Eliana Goncalves-Alves , Jiayi Yao , Laia
- Wnt pathway inhibition with the porcupine inhibitor LGK974 decreases trabecular bone but not fibrosis in a murine model with fibrotic bone
Authors Hsuan Lung, Kelly L Wentworth, Tania Moody, Ariane Zamarioli, Apsara Ram, Gauri Ganesh, Misun
- Expanding role of CXCR2 and therapeutic potential of CXCR2 antagonists in inflammatory diseases and cancers
be used as a biomarker and a new target for diabetes and that CXCR2 antagonists may also attenuate lung
- GPR176 promotes fibroblast-to-myofibroblast transition in organ fibrosis progression
In gene expression analysis of mouse lungs with induced fibrosis, eight GPCRs were identified, showing actin (αSMA), the profibrotic factor transforming growth factor β1 (TGFβ1), and collagen in a human lung Similar to the lung fibrosis model, increased Gpr176 expression was also observed in other organs affected expressed Gpr176 compared to alveolar epithelial cells, endothelial cells, and macrophages in the fibrotic lung
- Glucose and HODEs regulate Aspergillus ochraceus quorum sensing through the GprC-AcyA pathway
Authors Jing Gao, Huiqing Liu, Yuxin Jin, Yunbo Luo, Kunlun Huang, Zhihong Liang Tags Cell communication
- DANGER Signals Activate G-Protein Receptor Kinases Suppressing Neutrophil Function and Predisposing to Infection After Tissue Trauma
Either GRK2 or HDAC inhibition prevented loss of mouse lung bacterial clearance, but only the combination