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She is currently working to understand the signaling and degradation of GPCRs in disease states to help

characterized the role of RGS4 and RGS5 in airway hyperresponsiveness and lung fibrosis in acute and chronic

psoriasis pathogenesis via amplifying IL-23/IL-17 axis signal pathway Published date September 10, 2024 Abstract indicated that beclomethasone dipropionate (BDP), an agonist of GPR97, attenuated the psoriasis-like skin disease

decreases trabecular bone but not fibrosis in a murine model with fibrotic bone Published date May 1, 2024 Abstract Ram, Gauri Ganesh, Misun Kang, Sunita Ho, Edward C Hsiao Tags Wnt pathway inhibition , fibrotic bone disease

proliferation of T-cell lymphoma cells through the enhancement of apoptosis Published date November 3, 2023 Abstract " Purpose: Peripheral T-cell lymphoma (PTCL) is an aggressive disease with a poor prognosis.

Activation in Pancreatic Cancer Cells: Implications for Targeted Therapy Published date November 1, 2022 Abstract Pancreatic ductal adenocarcinoma (PDAC) remains an aggressive disease that is expected to become the

Nexus: Identification of an Aberrant Therapeutic Target in Ovarian Cancer Published date April 18, 2024 Abstract primarily due to the lack of early diagnostic tools, effective targeted therapy, and clear understanding of disease

influence G protein gamma (Gγ) prenylation under suboptimal conditions Published date September 20, 2023 Abstract prenylation contributes to multiple disorders, including cancers and vascular and neurodegenerative diseases

multitissue transcriptomic analysis reveals complex neuroendocrine regulatory networks mediated by spinal cord injury-induced immunodeficiency Published date September 30, 2023 Abstract "Background: Spinal cord which causes loss of sensory and motor function in the body below the level of injury, is a devastating disease blood pressure and catecholamine levels in plasma), were assessed in rats in the high-level (T3) spinal cord injury (T3-SCI) group and the low-level (T10) spinal cord injury (T10-SCI) group.

in a sex-selective manner and how this can influence drug discovery in the area of neurodegenerative diseases

a track record in exploring GPCR structure-function relationships in the context of cardiovascular disease

processes, making them a focal point of scientific research with implications for human health and disease

Cirl Anne Bormann BAI1/ADGRB1-mediated Regulation of Mitochondrial Morphology in Axons Joseph Duman Abstract Mihaylov Abstract Only available for AGPCR 24 Attendees Authors & Affiliations "Flynn, Helen R.2, Sampedro-Castaneda then moved to King's College London, where my interest and passion for kinases in brain health and disease Intricacies Of Complex Assembly And Ligand Interaction In The Adhesion GPCR Latrophilin/Cirl Anne Bormann Abstract

studies to address the functional role of these dramatic conformational changes and the relationship to disease continues to engineer the enzyme to optimize its potential as a treatment for cocaine abuse, a debilitating disease

physiological and pharmacological principles that underlie the workings of adhesion GPCRs in health and disease

neurotransmitters and how they might underlie brain and behavior disorders such as schizophrenia, Parkinson's disease

Jurgen Wess’s lab at the National Institute of Diabetes, Digestive and Kidney Diseases (NIDDK) - NIH,

GPRC5D are highly effective in relapsed myeloma after CAR T-cell therapy Published date December 5, 2024 Abstract The median time to relapse after CAR T-cell therapy was 5 months, 53% had the extramedullary disease

neurotransmitters and how they might underlie brain and behavior disorders such as schizophrenia, Parkinson's disease

Confo Therapeutics ) as a team and project leader for antibody discovery for metabolic and inflammatory diseases

of growth factors and their signaling mechanisms in development, adult tissue homeostasis, and human diseases

McGill, his laboratory has two main axes of research: 1) Studying interindividual vulnerability to chronic

in a sex-selective manner and how this can influence drug discovery in the area of neurodegenerative diseases

interested in characterizing novel G protein-coupled receptors (GPCRs) ligands for the treatment of chronic

Sachdev is an early career researcher in the National Institute of Diabetes and Digestive and Kidney Diseases he aims to apply this knowledge to develop novel chemical treatments for neuronal and cardiovascular diseases

reduced ability to respond to progesterone: a study based on RNA-seq Published date August 8, 2023 Abstract Patients with ERα-positive/PR-negative tumors have shorter disease-free and overall survival than patients

neurotransmitters and how they might underlie brain and behavior disorders such as schizophrenia, Parkinson's disease

Chemokine Interleukin-8 to Facilitate Viral Replication by Regulating Ca2+ Flux Published date May 29, 2023 Abstract and more effort is needed to develop economical and efficient vaccines to control or eliminate this disease