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94 items found for "Eunice S Wang"
- A Model for the Signal Initiation Complex Between Arrestin-3 and the Src Family Kinase Fgr
Arrestins regulate a wide range of signaling events, most notably when bound to active G protein-coupled
- The development of modulators for lysophosphatidic acid receptors: A comprehensive review
Lysophosphatidic acids (LPAs) are bioactive phospholipids implicated in a wide range of cellular activities
- GPCRs are not simple on-off switches: deep dive into GPCR-ligand interactions
GPCRs are present in a range of conformations, and the binding of a ligand, as well as interactions with desensitization), the same drug acting on the same receptor in the same cellular context can produce a range
- GPCRS: AN ODYSSEY FROM STRUCTURE, SIGNALING AND REGULATION TO THERAPEUTICS
Coupled with their ability to respond to a highly diverse range of chemical stimuli, they represent the
- Chemical signaling regulates axon regeneration via the GPCR-Gqα pathway in Caenorhabditis elegans
Chemical communication controls a wide range of behaviors via conserved signaling networks.
- Constitutive, Basal, and β-Alanine-Mediated Activation of the Human Mas-Related G Protein-Coupled ..
Consequently, the dynamic range for IL-6 detection as an assay for β-alanine-mediated activation of MRGPRD
- Neuronal Gα subunits required for the control of response to polystyrene nanoparticles in the ...
Neuronal Gα subunits required for the control of response to polystyrene nanoparticles in the range of
- Unlocking the Therapeutic Potential of Previously Undruggable GPCRs
However, the receptors that these medicines target have been described as the ‘low-hanging’ fruit, and There are approximately 800 human GPCRs in the superfamily, controlling a broad range of physiological Orion’s receptor antagonist analogs have demonstrated powerful efficacies across a range of animal models
- GPCR News Flash! Top Updates You Can't-Miss! + University CheatSheet is finally available! ❄ Dec 2 - 8, 2024
Structure-guided design of a peripherally restricted chemogenetic system Hye Jin Kang , Brian E Krumm We are bursting with pride in sharing it with you, and we sincerely want to thank you for your support
- Structural landscape of the Chemokine Receptor system
activation will pave the way for significant advancements in the development of therapeutics for a wide range